ENSG00000105656

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262809 ENSG00000105656 No_inf pgKDN_inf ELL protein_coding protein_coding 14.05743 11.53198 14.25635 0.3958085 0.2347747 0.3057258 13.1986039 10.4388742 14.25635 0.3373817 0.2347747 0.4492684 0.9401417 0.906650 1 0.093350 0.000368101 0.000368101 FALSE  
ENST00000596915 ENSG00000105656 No_inf pgKDN_inf ELL protein_coding retained_intron 14.05743 11.53198 14.25635 0.3958085 0.2347747 0.3057258 0.3810104 0.9986223 0.00000 0.2877904 0.0000000 -6.6562423 0.0315000 0.085725 0 -0.085725 0.014016381 0.000368101 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105656 E001 0.1272623 0.0123382505 0.4334901460   19 18442663 18442664 2 - 0.000 0.105 10.377
ENSG00000105656 E002 87.3559429 0.0002328715 0.0051819482 0.050916960 19 18442665 18444515 1851 - 1.908 1.985 0.260
ENSG00000105656 E003 18.9271811 0.0055716817 0.6861950475 0.870355197 19 18444516 18444750 235 - 1.283 1.315 0.111
ENSG00000105656 E004 14.4742806 0.0011628597 0.4327335604 0.710188589 19 18444751 18444868 118 - 1.214 1.158 -0.198
ENSG00000105656 E005 8.1762944 0.0017843946 0.9885620874 1.000000000 19 18445224 18445268 45 - 0.960 0.963 0.014
ENSG00000105656 E006 0.0000000       19 18445269 18445399 131 -      
ENSG00000105656 E007 0.0000000       19 18446146 18446308 163 -      
ENSG00000105656 E008 15.8363709 0.0013441662 0.0649240409 0.256728957 19 18446309 18446480 172 - 1.158 1.292 0.473
ENSG00000105656 E009 9.1452648 0.0388647713 0.9587715008 0.990206226 19 18446748 18446814 67 - 1.009 1.001 -0.032
ENSG00000105656 E010 35.2679094 0.0004330527 0.1445907894 0.404807068 19 18450477 18450975 499 - 1.588 1.521 -0.228
ENSG00000105656 E011 8.7311933 0.0018554819 0.1389883825 0.396456496 19 18451552 18451648 97 - 1.045 0.909 -0.507
ENSG00000105656 E012 9.5759613 0.0045263916 0.1029475712 0.335391733 19 18458205 18458329 125 - 1.086 0.937 -0.549
ENSG00000105656 E013 16.2046510 0.0009530446 0.6649811039 0.860707996 19 18461578 18461852 275 - 1.247 1.219 -0.099
ENSG00000105656 E014 10.9556542 0.0501296188 0.5904330842 0.818685707 19 18465412 18465575 164 - 1.109 1.035 -0.270
ENSG00000105656 E015 10.7151184 0.0013482155 0.6137236228 0.832080810 19 18465797 18465918 122 - 1.086 1.046 -0.147
ENSG00000105656 E016 0.2539903 0.0160895008 0.1774038750   19 18470976 18471035 60 - 0.000 0.189 13.400
ENSG00000105656 E017 1.1425607 0.0136488938 0.0003588307 0.006735043 19 18472407 18472834 428 - 0.000 0.539 15.368
ENSG00000105656 E018 6.4571009 0.0021613395 0.8491874523 0.946429349 19 18472835 18472882 48 - 0.880 0.862 -0.067
ENSG00000105656 E019 0.2536433 0.0160825866 0.1774029621   19 18475814 18475933 120 - 0.000 0.189 13.400
ENSG00000105656 E020 10.8697461 0.0282542035 0.0318657271 0.168693181 19 18521921 18522116 196 - 1.164 0.937 -0.830

Help

Please Click HERE to learn more details about the results from DEXseq.