ENSG00000105671

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000247003 ENSG00000105671 No_inf pgKDN_inf DDX49 protein_coding protein_coding 26.03628 18.41701 29.40089 1.262991 2.940472 0.674529 13.3878936 7.346851 16.957354 1.2871855 1.400492 1.205601 0.52915000 0.416575 0.614625 0.19805 0.78429139 0.03583715 FALSE  
ENST00000599156 ENSG00000105671 No_inf pgKDN_inf DDX49 protein_coding protein_coding_CDS_not_defined 26.03628 18.41701 29.40089 1.262991 2.940472 0.674529 5.3508852 2.737707 7.687188 1.8078854 2.590429 1.486103 0.17534167 0.132200 0.238900 0.10670 0.78461951 0.03583715 FALSE  
ENST00000629999 ENSG00000105671 No_inf pgKDN_inf DDX49 protein_coding nonsense_mediated_decay 26.03628 18.41701 29.40089 1.262991 2.940472 0.674529 0.7991149 1.497733 0.000000 0.5775181 0.000000 -7.236237 0.03920833 0.084300 0.000000 -0.08430 0.03583715 0.03583715 FALSE  
MSTRG.14811.1 ENSG00000105671 No_inf pgKDN_inf DDX49 protein_coding   26.03628 18.41701 29.40089 1.262991 2.940472 0.674529 3.5119859 5.581423 2.428358 1.3229848 1.173680 -1.197306 0.15550000 0.299925 0.073525 -0.22640 0.20236050 0.03583715 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105671 E001 0.6338583 0.0151432001 0.011948376 0.09023015 19 18919685 18919704 20 + 0.000 0.371 11.782
ENSG00000105671 E002 1.3854087 0.0125763403 0.001602442 0.02152044 19 18919705 18919714 10 + 0.087 0.568 3.607
ENSG00000105671 E003 2.0020825 0.0074432415 0.003548751 0.03910078 19 18919715 18919726 12 + 0.221 0.654 2.400
ENSG00000105671 E004 2.3728558 0.0093916705 0.003328003 0.03733982 19 18919727 18919727 1 + 0.276 0.703 2.192
ENSG00000105671 E005 2.3728558 0.0093916705 0.003328003 0.03733982 19 18919728 18919728 1 + 0.276 0.703 2.192
ENSG00000105671 E006 3.5604473 0.0131093350 0.316569615 0.60949793 19 18919729 18919737 9 + 0.589 0.726 0.584
ENSG00000105671 E007 12.4070931 0.0011644862 0.287305907 0.58068416 19 18919738 18919856 119 + 1.162 1.082 -0.289
ENSG00000105671 E008 11.0737125 0.0011978353 0.361576781 0.65102350 19 18920580 18920650 71 + 1.113 1.041 -0.261
ENSG00000105671 E009 10.3740788 0.0016438786 0.898265609 0.96654412 19 18920651 18920703 53 + 1.058 1.052 -0.022
ENSG00000105671 E010 0.3810317 0.0232559444 0.073426643   19 18920834 18920844 11 + 0.000 0.258 13.393
ENSG00000105671 E011 0.8805755 0.0153892105 0.028675089 0.15855786 19 18920845 18920909 65 + 0.087 0.418 2.870
ENSG00000105671 E012 13.8946728 0.0011170312 0.001959824 0.02517293 19 18921663 18921746 84 + 1.268 1.030 -0.849
ENSG00000105671 E013 7.6089977 0.0029044673 0.014524888 0.10277950 19 18921747 18921748 2 + 1.032 0.788 -0.927
ENSG00000105671 E014 0.2537079 0.3128797209 0.248738949   19 18921749 18921842 94 + 0.000 0.188 12.237
ENSG00000105671 E015 20.4268509 0.0078103857 0.195842692 0.47628533 19 18921843 18921964 122 + 1.369 1.281 -0.308
ENSG00000105671 E016 0.3549719 0.0158024263 0.143887559   19 18921965 18922325 361 + 0.222 0.000 -13.687
ENSG00000105671 E017 7.6559298 0.0041265725 0.372746727 0.66058874 19 18922326 18922331 6 + 0.974 0.890 -0.319
ENSG00000105671 E018 26.8595949 0.0005480050 0.064109766 0.25497354 19 18922332 18922513 182 + 1.487 1.389 -0.338
ENSG00000105671 E019 15.7487930 0.0010720534 0.918640948 0.97439961 19 18922604 18922697 94 + 1.224 1.222 -0.007
ENSG00000105671 E020 8.0485948 0.0019883902 0.810930993 0.93041083 19 18922698 18922709 12 + 0.964 0.946 -0.067
ENSG00000105671 E021 11.4973541 0.0011934345 0.629673685 0.84118259 19 18922710 18922744 35 + 1.074 1.119 0.162
ENSG00000105671 E022 17.7157184 0.0044957193 0.733708249 0.89417740 19 18924233 18924308 76 + 1.257 1.287 0.105
ENSG00000105671 E023 14.7195256 0.0009951962 0.274190981 0.56772944 19 18924623 18924652 30 + 1.230 1.153 -0.271
ENSG00000105671 E024 15.6096515 0.0011706219 0.709093250 0.88219961 19 18924653 18924699 47 + 1.230 1.208 -0.078
ENSG00000105671 E025 1.7446615 0.0094262053 0.051527179 0.22513503 19 18924700 18924852 153 + 0.276 0.568 1.607
ENSG00000105671 E026 0.5081066 0.0165350363 0.028833335 0.15910549 19 18924853 18924881 29 + 0.000 0.318 13.791
ENSG00000105671 E027 24.0356408 0.0006495602 0.724928111 0.88954180 19 18924882 18924979 98 + 1.405 1.389 -0.054
ENSG00000105671 E028 0.2543986 0.0161626084 0.185612944   19 18924980 18925129 150 + 0.000 0.188 12.883
ENSG00000105671 E029 0.3645426 0.2002395538 0.751391028   19 18925130 18925188 59 + 0.160 0.104 -0.716
ENSG00000105671 E030 24.4895992 0.0005902804 0.445373669 0.71976213 19 18926303 18926377 75 + 1.423 1.384 -0.135
ENSG00000105671 E031 0.0000000       19 18927744 18927765 22 +      
ENSG00000105671 E032 28.1774369 0.0079559098 0.932412827 0.98035186 19 18927766 18927854 89 + 1.465 1.464 -0.003
ENSG00000105671 E033 24.8066555 0.0097477104 0.632744315 0.84275280 19 18927965 18928036 72 + 1.393 1.430 0.128
ENSG00000105671 E034 60.4707172 0.0002666468 0.001748311 0.02300400 19 18928128 18929189 1062 + 1.729 1.846 0.396

Help

Please Click HERE to learn more details about the results from DEXseq.