ENSG00000105698

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000222305 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding protein_coding 134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 66.155098 50.676496 83.084211 5.2174629 3.9608470 0.71314655 0.49557500 0.412175 0.595625 0.183450 0.21214767 0.002951171 FALSE  
ENST00000379134 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding protein_coding 134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 22.732695 16.322795 25.908521 6.9698009 10.4983664 0.66621164 0.16136667 0.124225 0.173225 0.049000 0.96510211 0.002951171 FALSE  
ENST00000594064 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding protein_coding 134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 3.581990 7.996905 0.000000 3.0933646 0.0000000 -9.64510091 0.02622500 0.060450 0.000000 -0.060450 0.00748441 0.002951171 FALSE  
ENST00000596380 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding protein_coding 134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 9.071433 10.701891 8.988720 5.2342498 6.3145921 -0.25142148 0.06280000 0.079150 0.056925 -0.022225 0.84205999 0.002951171 FALSE  
ENST00000599625 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding protein_coding 134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 6.090408 7.214259 0.000000 7.2142586 0.0000000 -9.49670574 0.04636667 0.059050 0.000000 -0.059050 0.90867327 0.002951171 FALSE  
MSTRG.15014.1 ENSG00000105698 No_inf pgKDN_inf USF2 protein_coding   134.9615 125.9188 141.6643 6.72588 8.204552 0.1699698 7.919514 7.578851 7.749317 0.4120647 0.4397031 0.03204826 0.05933333 0.061050 0.055225 -0.005825 0.93752781 0.002951171 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105698 E001 22.4683018 6.243507e-04 2.761363e-01 5.695708e-01 19 35268567 35268961 395 + 1.335 1.402 0.235
ENSG00000105698 E002 6.0232449 2.334683e-03 3.949538e-01 6.797536e-01 19 35268962 35268977 16 + 0.797 0.889 0.357
ENSG00000105698 E003 5.1548110 9.921463e-03 6.726682e-01 8.644460e-01 19 35268978 35269064 87 + 0.763 0.813 0.199
ENSG00000105698 E004 1.3425441 1.753474e-02 8.200779e-01 9.346424e-01 19 35269065 35269101 37 + 0.387 0.352 -0.202
ENSG00000105698 E005 1.1064014 2.543345e-02 7.008898e-01 8.781802e-01 19 35269102 35269107 6 + 0.292 0.352 0.383
ENSG00000105698 E006 1.4784005 8.907304e-03 5.203088e-01 7.747076e-01 19 35269108 35269114 7 + 0.342 0.439 0.547
ENSG00000105698 E007 6.3378143 1.518215e-02 5.379529e-01 7.868468e-01 19 35269115 35269163 49 + 0.900 0.829 -0.273
ENSG00000105698 E008 0.6255492 6.635758e-01 5.584050e-01 8.000908e-01 19 35269281 35269358 78 + 0.093 0.301 2.064
ENSG00000105698 E009 17.9586556 1.139549e-03 6.302688e-01 8.414297e-01 19 35269446 35269492 47 + 1.294 1.261 -0.116
ENSG00000105698 E010 0.4805351 1.531148e-02 3.398517e-01   19 35269493 35269580 88 + 0.235 0.097 -1.524
ENSG00000105698 E011 26.4883387 9.248043e-04 3.324497e-01 6.245373e-01 19 35269581 35269600 20 + 1.467 1.411 -0.192
ENSG00000105698 E012 69.6413797 2.668589e-04 4.725594e-02 2.135843e-01 19 35269601 35269699 99 + 1.884 1.813 -0.238
ENSG00000105698 E013 0.8524383 1.678863e-02 7.502663e-01 9.014829e-01 19 35269700 35269802 103 + 0.292 0.243 -0.354
ENSG00000105698 E014 106.7067181 1.636942e-03 1.029448e-01 3.353917e-01 19 35269803 35270003 201 + 2.058 2.005 -0.177
ENSG00000105698 E015 6.3204603 1.906360e-02 2.115165e-02 1.315339e-01 19 35270004 35270262 259 + 0.705 0.978 1.061
ENSG00000105698 E016 5.9665300 4.549828e-03 2.707185e-03 3.192856e-02 19 35270263 35270446 184 + 0.639 0.978 1.341
ENSG00000105698 E017 36.7866603 1.025484e-03 5.463676e-01 7.921449e-01 19 35270447 35270449 3 + 1.592 1.562 -0.102
ENSG00000105698 E018 64.9851966 2.538146e-04 3.178920e-01 6.106347e-01 19 35270450 35270493 44 + 1.838 1.801 -0.124
ENSG00000105698 E019 115.5767896 1.651006e-04 2.552042e-01 5.471532e-01 19 35270494 35270597 104 + 2.082 2.051 -0.104
ENSG00000105698 E020 67.8467816 2.846373e-04 7.075792e-02 2.694306e-01 19 35270718 35270758 41 + 1.870 1.804 -0.220
ENSG00000105698 E021 92.7862850 2.414063e-04 8.885257e-01 9.627629e-01 19 35270759 35270805 47 + 1.970 1.974 0.015
ENSG00000105698 E022 0.7332970 5.175819e-02 9.616181e-01 9.916239e-01 19 35270977 35271000 24 + 0.235 0.243 0.061
ENSG00000105698 E023 1.2030668 2.121412e-01 4.129601e-01 6.939527e-01 19 35271001 35271082 82 + 0.427 0.243 -1.159
ENSG00000105698 E024 107.9440093 2.122196e-04 3.845210e-01 6.706889e-01 19 35271083 35271141 59 + 2.024 2.049 0.084
ENSG00000105698 E025 3.2473575 4.353713e-03 3.879407e-03 4.154725e-02 19 35275082 35275425 344 + 0.387 0.778 1.798
ENSG00000105698 E026 2.4634285 1.808577e-01 4.842574e-01 7.484508e-01 19 35275783 35275900 118 + 0.465 0.602 0.647
ENSG00000105698 E027 12.5038342 1.121398e-03 3.312611e-09 2.581826e-07 19 35276977 35278214 1238 + 0.797 1.312 1.887
ENSG00000105698 E028 11.9580872 1.131626e-03 2.205095e-06 9.219349e-05 19 35278215 35278697 483 + 0.859 1.267 1.490
ENSG00000105698 E029 144.5177723 1.464728e-04 9.452726e-01 9.850897e-01 19 35278698 35278792 95 + 2.164 2.162 -0.005
ENSG00000105698 E030 2.4754431 1.129813e-02 1.595503e-01 4.269503e-01 19 35278793 35278945 153 + 0.428 0.628 0.954
ENSG00000105698 E031 85.4018167 2.156440e-04 3.129095e-01 6.062982e-01 19 35278946 35278969 24 + 1.953 1.920 -0.108
ENSG00000105698 E032 157.3606931 1.310307e-04 3.850791e-01 6.712126e-01 19 35278970 35279074 105 + 2.210 2.190 -0.067
ENSG00000105698 E033 5.8093406 2.442605e-03 8.306070e-02 2.970293e-01 19 35279075 35279166 92 + 0.725 0.916 0.749
ENSG00000105698 E034 335.2292461 9.118223e-05 1.887370e-01 4.672424e-01 19 35279167 35279821 655 + 2.516 2.536 0.066

Help

Please Click HERE to learn more details about the results from DEXseq.