ENSG00000105700

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000222307 ENSG00000105700 No_inf pgKDN_inf KXD1 protein_coding protein_coding 67.34872 52.68612 79.24219 1.942005 3.288658 0.5887541 45.696152 34.668209 52.7581151 2.9623446 1.7560073 0.6056371 0.67809167 0.65595 0.667850 0.011900 0.98713973 0.01723884 FALSE  
ENST00000598830 ENSG00000105700 No_inf pgKDN_inf KXD1 protein_coding protein_coding 67.34872 52.68612 79.24219 1.942005 3.288658 0.5887541 4.054089 6.335874 2.3843834 0.4648670 0.6501570 -1.4061648 0.06678333 0.12125 0.030475 -0.090775 0.04718670 0.01723884 FALSE  
ENST00000599000 ENSG00000105700 No_inf pgKDN_inf KXD1 protein_coding protein_coding 67.34872 52.68612 79.24219 1.942005 3.288658 0.5887541 2.087943 0.000000 6.2638287 0.0000000 3.7013660 9.2932023 0.02649167 0.00000 0.079475 0.079475 0.53500495 0.01723884 FALSE  
ENST00000602094 ENSG00000105700 No_inf pgKDN_inf KXD1 protein_coding protein_coding 67.34872 52.68612 79.24219 1.942005 3.288658 0.5887541 2.087030 4.003854 0.8165371 0.7267109 0.2748899 -2.2798366 0.03575833 0.07590 0.010200 -0.065700 0.01723884 0.01723884 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105700 E001 0.0000000       19 18557762 18557805 44 +      
ENSG00000105700 E002 0.0000000       19 18557806 18557837 32 +      
ENSG00000105700 E003 0.0000000       19 18557838 18557869 32 +      
ENSG00000105700 E004 0.0000000       19 18557870 18557875 6 +      
ENSG00000105700 E005 0.0000000       19 18557876 18557878 3 +      
ENSG00000105700 E006 0.0000000       19 18557879 18557887 9 +      
ENSG00000105700 E007 0.0000000       19 18557888 18557891 4 +      
ENSG00000105700 E008 0.0000000       19 18557892 18557897 6 +      
ENSG00000105700 E009 0.0000000       19 18557898 18557914 17 +      
ENSG00000105700 E010 0.0000000       19 18557915 18557949 35 +      
ENSG00000105700 E011 0.0000000       19 18558539 18558604 66 +      
ENSG00000105700 E012 0.0000000       19 18558654 18558766 113 +      
ENSG00000105700 E013 0.0000000       19 18558827 18559111 285 +      
ENSG00000105700 E014 0.0000000       19 18559112 18559130 19 +      
ENSG00000105700 E015 0.0000000       19 18559131 18559172 42 +      
ENSG00000105700 E016 0.0000000       19 18559173 18559285 113 +      
ENSG00000105700 E017 0.0000000       19 18559286 18559580 295 +      
ENSG00000105700 E018 8.5256381 0.0030005536 6.997131e-10 6.166393e-08 19 18559581 18560099 519 + 0.550 1.197 2.532
ENSG00000105700 E019 8.1596468 0.0375297591 2.124939e-02 1.318376e-01 19 18560100 18560419 320 + 0.801 1.083 1.062
ENSG00000105700 E020 3.7090765 0.0039789713 8.419443e-02 2.996333e-01 19 18560420 18560550 131 + 0.550 0.772 0.947
ENSG00000105700 E021 3.9701446 0.0782033353 5.553696e-02 2.347470e-01 19 18561520 18561779 260 + 0.521 0.825 1.297
ENSG00000105700 E022 8.9365497 0.0020357905 1.785691e-04 3.809709e-03 19 18561780 18562035 256 + 0.785 1.144 1.343
ENSG00000105700 E023 19.3009497 0.0007678577 8.646564e-01 9.531832e-01 19 18562036 18562090 55 + 1.311 1.304 -0.024
ENSG00000105700 E024 34.9465758 0.0004535778 5.835180e-02 2.418649e-01 19 18562091 18562157 67 + 1.596 1.509 -0.297
ENSG00000105700 E025 65.0009203 0.0004346563 3.565081e-03 3.923262e-02 19 18564869 18565021 153 + 1.864 1.768 -0.321
ENSG00000105700 E026 1.7067743 0.0078656432 7.310499e-01 8.931981e-01 19 18565134 18565190 57 + 0.455 0.407 -0.256
ENSG00000105700 E027 35.4507996 0.0032507135 1.278396e-01 3.790595e-01 19 18567132 18567178 47 + 1.596 1.523 -0.251
ENSG00000105700 E028 0.1176306 0.0118593293 5.938236e-01   19 18567179 18567318 140 + 0.090 0.000 -8.678
ENSG00000105700 E029 26.1132359 0.0012130245 7.687852e-03 6.726745e-02 19 18568402 18568679 278 + 1.499 1.351 -0.511
ENSG00000105700 E030 0.0000000       19 18568680 18568689 10 +      
ENSG00000105700 E031 12.9901732 0.0034978038 6.117230e-01 8.310655e-01 19 18568690 18568829 140 + 1.123 1.168 0.159
ENSG00000105700 E032 96.3298286 0.0007409175 2.462211e-01 5.368803e-01 19 18568830 18569387 558 + 1.971 2.006 0.118

Help

Please Click HERE to learn more details about the results from DEXseq.