ENSG00000105879

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000420796 ENSG00000105879 No_inf pgKDN_inf CBLL1 protein_coding protein_coding 10.69006 10.3713 11.69214 0.3592048 0.7465833 0.1727857 0.2234437 0.0000000 0.5985009 0.0000000 0.2971911 5.9271875 0.01986667 0.000000 0.052550 0.052550 0.2617661 0.0416642 FALSE TRUE
ENST00000432748 ENSG00000105879 No_inf pgKDN_inf CBLL1 protein_coding nonsense_mediated_decay 10.69006 10.3713 11.69214 0.3592048 0.7465833 0.1727857 0.7630725 0.9513373 0.7088501 0.6448844 0.7088501 -0.4193518 0.06644167 0.086125 0.057750 -0.028375 0.8326907 0.0416642 FALSE TRUE
ENST00000440859 ENSG00000105879 No_inf pgKDN_inf CBLL1 protein_coding protein_coding 10.69006 10.3713 11.69214 0.3592048 0.7465833 0.1727857 6.2971373 4.9273164 8.1268784 2.0219373 0.8015414 0.7207483 0.59252500 0.483925 0.709475 0.225550 0.8177877 0.0416642 FALSE TRUE
ENST00000698938 ENSG00000105879 No_inf pgKDN_inf CBLL1 protein_coding protein_coding 10.69006 10.3713 11.69214 0.3592048 0.7465833 0.1727857 1.4124603 0.4670743 1.5171681 0.4670743 1.5171681 1.6785730 0.13412500 0.046250 0.113125 0.066875 1.0000000 0.0416642 FALSE TRUE
MSTRG.26716.10 ENSG00000105879 No_inf pgKDN_inf CBLL1 protein_coding   10.69006 10.3713 11.69214 0.3592048 0.7465833 0.1727857 1.1401318 3.4203955 0.0000000 1.5670809 0.0000000 -8.4222311 0.10812500 0.324375 0.000000 -0.324375 0.0416642 0.0416642 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000105879 E001 0.0000000       7 107743073 107743150 78 +      
ENSG00000105879 E002 0.3526461 0.021407361 0.109883731   7 107743799 107743948 150 + 0.223 0.000 -11.312
ENSG00000105879 E003 0.0000000       7 107743949 107744141 193 +      
ENSG00000105879 E004 0.0000000       7 107744142 107744144 3 +      
ENSG00000105879 E005 0.1271363 0.012414453 0.523427160   7 107744145 107744154 10 + 0.000 0.103 10.901
ENSG00000105879 E006 1.6174637 0.421024749 0.484769153 0.74880153 7 107744155 107744176 22 + 0.277 0.533 1.434
ENSG00000105879 E007 0.2346346 0.015630628 0.252470115   7 107744437 107744837 401 + 0.160 0.000 -11.813
ENSG00000105879 E008 8.5165459 0.028812221 0.259144196 0.55169665 7 107748880 107749047 168 + 1.007 0.944 -0.234
ENSG00000105879 E009 0.3625611 0.016493687 0.602564003   7 107749048 107749316 269 + 0.160 0.103 -0.735
ENSG00000105879 E010 0.6179682 0.600828054 0.844387647 0.94446594 7 107752545 107752566 22 + 0.161 0.256 0.847
ENSG00000105879 E011 0.8643421 0.369123793 0.667331709 0.86152988 7 107752567 107752617 51 + 0.223 0.317 0.678
ENSG00000105879 E012 2.7570622 0.005399651 0.006980265 0.06299759 7 107753411 107753413 3 + 0.701 0.369 -1.583
ENSG00000105879 E013 7.7533346 0.093639952 0.146843345 0.40790322 7 107753414 107753511 98 + 1.006 0.856 -0.568
ENSG00000105879 E014 7.9085378 0.007078527 0.228995133 0.51770753 7 107753895 107753978 84 + 0.977 0.916 -0.228
ENSG00000105879 E015 0.0000000       7 107753979 107754183 205 +      
ENSG00000105879 E016 8.3983223 0.001614236 0.226899199 0.51512659 7 107755418 107755491 74 + 0.997 0.943 -0.199
ENSG00000105879 E017 0.0000000       7 107755492 107755592 101 +      
ENSG00000105879 E018 195.0879954 0.029699488 0.038908706 0.19094651 7 107758143 107761667 3525 + 2.243 2.341 0.326

Help

Please Click HERE to learn more details about the results from DEXseq.