ENSG00000106244

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000350498 ENSG00000106244 No_inf pgKDN_inf PDAP1 protein_coding protein_coding 193.6074 112.2207 241.8652 19.15929 19.93058 1.107796 20.798307 19.25043 20.797885 1.149997 0.4471543 0.1114904 0.12326667 0.181350 0.087625 -0.093725 0.03253402 0.03253402 FALSE  
ENST00000426447 ENSG00000106244 No_inf pgKDN_inf PDAP1 protein_coding nonsense_mediated_decay 193.6074 112.2207 241.8652 19.15929 19.93058 1.107796 68.641794 50.34055 80.749074 1.170799 1.8758608 0.6816167 0.38909167 0.488675 0.341625 -0.147050 0.44986995 0.03253402    
ENST00000496335 ENSG00000106244 No_inf pgKDN_inf PDAP1 protein_coding protein_coding_CDS_not_defined 193.6074 112.2207 241.8652 19.15929 19.93058 1.107796 8.375943 10.88637 4.463143 2.446832 2.5952636 -1.2844866 0.05778333 0.103950 0.021150 -0.082800 0.22311997 0.03253402    
ENST00000626285 ENSG00000106244 No_inf pgKDN_inf PDAP1 protein_coding protein_coding 193.6074 112.2207 241.8652 19.15929 19.93058 1.107796 93.481630 29.28037 132.909346 19.058068 23.0210812 2.1820528 0.41484167 0.201925 0.535750 0.333825 0.54112418 0.03253402    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106244 E001 3.4946759 0.0348263716 0.002446986 0.029630832 7 99392048 99392150 103 - 0.380 0.823 2.016
ENSG00000106244 E002 0.0000000       7 99392700 99392799 100 -      
ENSG00000106244 E003 153.1489505 0.0001347330 0.000372160 0.006909494 7 99394673 99396522 1850 - 2.150 2.224 0.245
ENSG00000106244 E004 76.1966463 0.0002402520 0.830757976 0.938740849 7 99396523 99396740 218 - 1.884 1.891 0.025
ENSG00000106244 E005 89.6632605 0.0001753439 0.091597563 0.314262648 7 99397862 99398013 152 - 1.981 1.932 -0.162
ENSG00000106244 E006 70.5906427 0.0002496797 0.001813081 0.023682907 7 99400303 99400424 122 - 1.903 1.799 -0.351
ENSG00000106244 E007 0.3711203 0.0164009027 0.525294773   7 99403317 99403397 81 - 0.091 0.180 1.139
ENSG00000106244 E008 39.5462225 0.0006592330 0.479684217 0.745323545 7 99403398 99403505 108 - 1.623 1.592 -0.109
ENSG00000106244 E009 0.7434018 0.0132705772 0.350897044 0.641143749 7 99403506 99403510 5 - 0.166 0.307 1.141
ENSG00000106244 E010 1.1240251 0.0106371577 0.066243870 0.259189394 7 99403511 99403525 15 - 0.166 0.447 1.949
ENSG00000106244 E011 0.4914576 0.0161245723 0.923320899   7 99404858 99404861 4 - 0.166 0.180 0.141
ENSG00000106244 E012 30.0734479 0.0004589249 0.991734755 1.000000000 7 99404862 99404953 92 - 1.492 1.492 0.000
ENSG00000106244 E013 9.9747402 0.0014304225 0.182413032 0.458831475 7 99408536 99408597 62 - 1.094 0.977 -0.429

Help

Please Click HERE to learn more details about the results from DEXseq.