ENSG00000106348

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000348127 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding protein_coding 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 2.4727726 0.9073542 2.6989306 0.6327102 1.0826279 1.5621726 0.10489167 0.038450 0.132600 0.094150 0.6404031 0.0199147 FALSE TRUE
ENST00000354269 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding protein_coding 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 0.4016088 0.0000000 1.0900281 0.0000000 0.8755071 6.7813966 0.01922500 0.000000 0.053350 0.053350 0.5009202 0.0199147 FALSE TRUE
ENST00000419067 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding protein_coding 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 0.6764570 1.6423782 0.1638438 0.9692545 0.1638438 -3.2486806 0.03010000 0.074025 0.008125 -0.065900 0.7925891 0.0199147 FALSE TRUE
ENST00000469328 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding nonsense_mediated_decay 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 5.4457224 8.5565822 1.2414609 1.3465201 1.2414609 -2.7751065 0.22633333 0.377275 0.059200 -0.318075 0.0199147 0.0199147 FALSE TRUE
ENST00000470772 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding protein_coding 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 0.3325534 0.0000000 0.9976602 0.0000000 0.9976602 6.6548653 0.01715833 0.000000 0.051475 0.051475 0.8370945 0.0199147 FALSE TRUE
ENST00000496200 ENSG00000106348 No_inf pgKDN_inf IMPDH1 protein_coding protein_coding 23.15464 22.64205 20.2544 0.5502877 0.3324228 -0.1606943 12.1354258 8.9051321 13.0356317 0.4537899 1.2417050 0.5492387 0.52910833 0.394650 0.644525 0.249875 0.1090759 0.0199147 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106348 E001 0.0000000       7 128392277 128392277 1 -      
ENSG00000106348 E002 0.1187032 0.0118796633 0.457746479   7 128392278 128392291 14 - 0.102 0.000 -10.034
ENSG00000106348 E003 0.6268098 0.0147672241 0.234610274 0.52367139 7 128392292 128392292 1 - 0.102 0.280 1.778
ENSG00000106348 E004 1.2522646 0.1172864589 0.144365504 0.40451515 7 128392293 128392300 8 - 0.184 0.449 1.778
ENSG00000106348 E005 47.5577508 0.0003221825 0.001129425 0.01645825 7 128392301 128392738 438 - 1.601 1.740 0.473
ENSG00000106348 E006 28.9788967 0.0005358434 0.103006514 0.33548027 7 128392739 128392849 111 - 1.421 1.512 0.312
ENSG00000106348 E007 39.7768265 0.0003809752 0.177271500 0.45181991 7 128392850 128393028 179 - 1.571 1.635 0.219
ENSG00000106348 E008 0.2536433 0.0160793197 0.302372375   7 128393722 128393738 17 - 0.000 0.162 12.457
ENSG00000106348 E009 0.2539903 0.0159887903 0.302600529   7 128394275 128394277 3 - 0.000 0.162 12.457
ENSG00000106348 E010 20.3086743 0.0009059596 0.353054295 0.64287373 7 128394278 128394361 84 - 1.290 1.353 0.218
ENSG00000106348 E011 26.5450568 0.0094297834 0.712333857 0.88380525 7 128394456 128394599 144 - 1.421 1.450 0.100
ENSG00000106348 E012 0.8608725 0.3732097820 0.804189453 0.92728687 7 128394600 128394888 289 - 0.253 0.280 0.194
ENSG00000106348 E013 17.3163418 0.0008330959 0.012850705 0.09455524 7 128394889 128394998 110 - 1.345 1.178 -0.590
ENSG00000106348 E014 8.5355835 0.0016730167 0.104794441 0.33844212 7 128394999 128395033 35 - 1.053 0.904 -0.553
ENSG00000106348 E015 20.4223592 0.0007314941 0.079284015 0.28875036 7 128395131 128395274 144 - 1.385 1.277 -0.378
ENSG00000106348 E016 17.2828422 0.0267010993 0.489205372 0.75215378 7 128396600 128396695 96 - 1.296 1.227 -0.244
ENSG00000106348 E017 14.9796360 0.0023249264 0.877318631 0.95840277 7 128396932 128397022 91 - 1.206 1.197 -0.033
ENSG00000106348 E018 14.8135946 0.0009395384 0.328017172 0.62050711 7 128398414 128398489 76 - 1.234 1.164 -0.246
ENSG00000106348 E019 18.5608827 0.0083348062 0.836985496 0.94156860 7 128398490 128398613 124 - 1.278 1.297 0.065
ENSG00000106348 E020 10.1260585 0.0015475556 0.202943096 0.48556175 7 128400095 128400134 40 - 0.976 1.091 0.422
ENSG00000106348 E021 11.4586544 0.0012012761 0.429239708 0.70758453 7 128400135 128400182 48 - 1.053 1.122 0.247
ENSG00000106348 E022 0.8872807 0.0398837976 0.009300020 0.07674182 7 128400183 128400204 22 - 0.000 0.413 13.995
ENSG00000106348 E023 17.7989672 0.0074817195 0.727045598 0.89090919 7 128400333 128400536 204 - 1.284 1.261 -0.083
ENSG00000106348 E024 4.3194542 0.0034328801 0.478870245 0.74480642 7 128400537 128400539 3 - 0.672 0.760 0.363
ENSG00000106348 E025 0.5081680 0.0162036793 0.064810821 0.25657842 7 128400540 128400671 132 - 0.000 0.280 13.362
ENSG00000106348 E026 0.7540721 0.0141586699 0.135714994 0.39157185 7 128400672 128400816 145 - 0.102 0.329 2.100
ENSG00000106348 E027 6.5235363 0.0021540017 0.705077410 0.88015663 7 128400817 128400831 15 - 0.850 0.892 0.161
ENSG00000106348 E028 6.4045535 0.0022760248 0.595336075 0.82207184 7 128400832 128400842 11 - 0.834 0.892 0.225
ENSG00000106348 E029 9.2019545 0.0015366018 0.907087611 0.97045252 7 128400843 128400891 49 - 1.011 1.003 -0.030
ENSG00000106348 E030 16.7266996 0.0008697906 0.058479399 0.24222624 7 128401015 128401116 102 - 1.313 1.184 -0.454
ENSG00000106348 E031 11.0611829 0.0013075641 0.005752930 0.05475182 7 128403706 128403754 49 - 1.191 0.962 -0.834
ENSG00000106348 E032 10.0663915 0.0097066369 0.004682528 0.04728467 7 128405767 128405865 99 - 1.169 0.904 -0.968
ENSG00000106348 E033 3.9896177 0.0037685175 0.017935924 0.11802992 7 128405866 128406052 187 - 0.834 0.543 -1.222
ENSG00000106348 E034 1.2451177 0.0109879771 0.306149727 0.59928660 7 128409289 128409352 64 - 0.254 0.413 1.000
ENSG00000106348 E035 0.5074773 0.0157509072 0.064965143 0.25678491 7 128409353 128409366 14 - 0.000 0.280 13.364
ENSG00000106348 E036 0.6244813 0.0147377905 0.234610296 0.52367139 7 128409367 128409440 74 - 0.102 0.280 1.778
ENSG00000106348 E037 0.1170040 0.0118269655 0.457670341   7 128409441 128409484 44 - 0.102 0.000 -12.753
ENSG00000106348 E038 0.0000000       7 128409485 128409486 2 -      
ENSG00000106348 E039 2.3071085 0.0063696142 0.138230832 0.39559279 7 128409756 128410252 497 - 0.620 0.413 -1.000

Help

Please Click HERE to learn more details about the results from DEXseq.