ENSG00000106460

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396667 ENSG00000106460 No_inf pgKDN_inf TMEM106B protein_coding protein_coding 6.823261 6.454982 7.259253 1.038844 0.7069275 0.1691606 0.1313913 0.2675871 0.000000 0.2675871 0.0000000 -4.7948685 0.03056667 0.063775 0.000000 -0.063775 0.84776967 0.04745414 FALSE TRUE
ENST00000396668 ENSG00000106460 No_inf pgKDN_inf TMEM106B protein_coding protein_coding 6.823261 6.454982 7.259253 1.038844 0.7069275 0.1691606 2.2401787 1.8831159 3.288275 1.1182440 1.1252875 0.8009490 0.34507500 0.349775 0.498275 0.148500 0.83366668 0.04745414 FALSE TRUE
ENST00000420833 ENSG00000106460 No_inf pgKDN_inf TMEM106B protein_coding nonsense_mediated_decay 6.823261 6.454982 7.259253 1.038844 0.7069275 0.1691606 1.7433872 0.4995289 2.446862 0.3058139 0.3068926 2.2695810 0.24590833 0.061925 0.336175 0.274250 0.08178239 0.04745414 TRUE TRUE
ENST00000704382 ENSG00000106460 No_inf pgKDN_inf TMEM106B protein_coding protein_coding_CDS_not_defined 6.823261 6.454982 7.259253 1.038844 0.7069275 0.1691606 0.7699277 1.3432078 0.000000 0.6051520 0.0000000 -7.0802395 0.09439167 0.180400 0.000000 -0.180400 0.04745414 0.04745414 FALSE TRUE
ENST00000704417 ENSG00000106460 No_inf pgKDN_inf TMEM106B protein_coding protein_coding 6.823261 6.454982 7.259253 1.038844 0.7069275 0.1691606 1.5993309 2.1626019 1.249321 1.2488009 1.2493211 -0.7867776 0.23787500 0.305675 0.134325 -0.171350 0.80329529 0.04745414 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106460 E001 0.0000000       7 12211270 12211293 24 +      
ENSG00000106460 E002 0.0000000       7 12211294 12211295 2 +      
ENSG00000106460 E003 0.0000000       7 12211296 12211299 4 +      
ENSG00000106460 E004 0.0000000       7 12211300 12211304 5 +      
ENSG00000106460 E005 0.1271363 0.0124046864 5.259482e-01   7 12211305 12211308 4 + 0.000 0.096 9.686
ENSG00000106460 E006 0.1271363 0.0124046864 5.259482e-01   7 12211309 12211322 14 + 0.000 0.096 11.285
ENSG00000106460 E007 0.4821082 0.0152912139 3.325062e-01   7 12211323 12211326 4 + 0.237 0.096 -1.547
ENSG00000106460 E008 1.2359594 0.0105738298 5.024905e-01 7.621494e-01 7 12211327 12211378 52 + 0.294 0.396 0.623
ENSG00000106460 E009 1.7249625 0.0077061003 5.618740e-01 8.020143e-01 7 12211379 12211425 47 + 0.389 0.475 0.453
ENSG00000106460 E010 0.0000000       7 12211426 12211439 14 +      
ENSG00000106460 E011 0.0000000       7 12211440 12211464 25 +      
ENSG00000106460 E012 0.0000000       7 12211465 12211547 83 +      
ENSG00000106460 E013 0.0000000       7 12211548 12211677 130 +      
ENSG00000106460 E014 0.1265070 0.0123388059 5.259722e-01   7 12214201 12214394 194 + 0.000 0.096 11.285
ENSG00000106460 E015 1.8227365 0.0132414896 4.771497e-01 7.435165e-01 7 12214809 12214848 40 + 0.502 0.396 -0.547
ENSG00000106460 E016 6.6447781 0.0022871688 5.865495e-03 5.554803e-02 7 12214849 12215027 179 + 1.008 0.717 -1.122
ENSG00000106460 E017 0.1170040 0.0119151444 5.505203e-01   7 12215604 12215804 201 + 0.094 0.000 -12.230
ENSG00000106460 E018 7.7672643 0.0018303417 5.735228e-02 2.394435e-01 7 12218458 12218521 64 + 1.028 0.842 -0.699
ENSG00000106460 E019 0.4979743 0.0242924011 3.105361e-01   7 12223746 12223919 174 + 0.094 0.242 1.623
ENSG00000106460 E020 18.6537150 0.0007971641 1.193825e-01 3.651755e-01 7 12224226 12224385 160 + 1.343 1.240 -0.360
ENSG00000106460 E021 12.2004398 0.0011780373 2.838076e-01 5.775169e-01 7 12229679 12229747 69 + 1.162 1.076 -0.310
ENSG00000106460 E022 12.4068495 0.0011379017 6.251760e-02 2.511676e-01 7 12229748 12229819 72 + 1.197 1.048 -0.535
ENSG00000106460 E023 0.1176306 0.0118988982 5.505539e-01   7 12230179 12230388 210 + 0.094 0.000 -12.230
ENSG00000106460 E024 9.1146526 0.0015752748 6.382958e-02 2.544032e-01 7 12230389 12230438 50 + 1.083 0.913 -0.627
ENSG00000106460 E025 0.4996734 0.0228765665 3.091727e-01   7 12230439 12230939 501 + 0.094 0.242 1.623
ENSG00000106460 E026 8.3767820 0.0145121842 5.257866e-02 2.279222e-01 7 12231062 12231115 54 + 1.066 0.857 -0.778
ENSG00000106460 E027 0.6179646 0.0142634348 6.339418e-01 8.435353e-01 7 12231116 12231529 414 + 0.171 0.242 0.623
ENSG00000106460 E028 245.9898737 0.0001102575 7.673367e-07 3.681987e-05 7 12231837 12243367 11531 + 2.367 2.415 0.161

Help

Please Click HERE to learn more details about the results from DEXseq.