ENSG00000106462

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000320356 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding protein_coding 20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 0.9164320 1.307682 0.0000000 0.8803560 0.0000000 -7.041859 0.04344167 0.055975 0.000000 -0.055975 0.49848277 0.01682178 FALSE TRUE
ENST00000460911 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding protein_coding 20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 9.4041731 3.434864 13.9070504 1.3047684 1.1457352 2.014334 0.45759167 0.173100 0.689600 0.516500 0.02887086 0.01682178 FALSE TRUE
ENST00000483967 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding protein_coding 20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 0.6090703 1.652677 0.0000000 1.2495378 0.0000000 -7.377364 0.02624167 0.069750 0.000000 -0.069750 0.51057398 0.01682178 FALSE TRUE
ENST00000492143 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding nonsense_mediated_decay 20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 1.5516780 2.490492 0.7558929 1.0063711 0.4497655 -1.706998 0.07679167 0.124825 0.036275 -0.088550 0.74633726 0.01682178 TRUE TRUE
ENST00000684400 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding retained_intron 20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 1.0178671 1.782330 0.3310688 0.3827183 0.1019234 -2.393701 0.04879167 0.085600 0.016525 -0.069075 0.16684943 0.01682178 TRUE FALSE
MSTRG.27066.16 ENSG00000106462 No_inf pgKDN_inf EZH2 protein_coding   20.90207 21.36569 20.16134 1.263558 0.4414023 -0.08366435 2.6479821 4.628554 0.0000000 1.5704458 0.0000000 -8.857531 0.12098333 0.206975 0.000000 -0.206975 0.01682178 0.01682178 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106462 E001 0.1265070 0.0123171362 6.412093e-01   7 148807257 148807382 126 - 0.000 0.088 11.869
ENSG00000106462 E002 0.1265070 0.0123171362 6.412093e-01   7 148807383 148807383 1 - 0.000 0.088 11.876
ENSG00000106462 E003 0.1265070 0.0123171362 6.412093e-01   7 148807384 148807384 1 - 0.000 0.088 11.876
ENSG00000106462 E004 0.5081680 0.0159179009 6.731540e-02 2.616632e-01 7 148807385 148807386 2 - 0.000 0.279 13.876
ENSG00000106462 E005 1.2342305 0.0151020739 7.261884e-01 8.903847e-01 7 148807387 148807419 33 - 0.315 0.371 0.340
ENSG00000106462 E006 1.5960014 0.0088280709 9.671818e-01 9.933727e-01 7 148807420 148807429 10 - 0.415 0.411 -0.022
ENSG00000106462 E007 1.7225084 0.0113377386 8.406310e-01 9.428146e-01 7 148807430 148807431 2 - 0.415 0.447 0.170
ENSG00000106462 E008 1.7225084 0.0113377386 8.406310e-01 9.428146e-01 7 148807432 148807434 3 - 0.415 0.447 0.170
ENSG00000106462 E009 2.8100595 0.0198172556 5.442533e-01 7.907588e-01 7 148807435 148807461 27 - 0.623 0.541 -0.370
ENSG00000106462 E010 5.1031655 0.0322887391 1.090954e-01 3.467266e-01 7 148807462 148807481 20 - 0.884 0.683 -0.801
ENSG00000106462 E011 6.8444610 0.0034533283 3.592204e-01 6.485978e-01 7 148807482 148807524 43 - 0.941 0.849 -0.348
ENSG00000106462 E012 6.1113176 0.0024274296 3.664612e-01 6.551621e-01 7 148807525 148807533 9 - 0.899 0.806 -0.360
ENSG00000106462 E013 26.8025492 0.0006440531 7.020658e-02 2.680997e-01 7 148807534 148807706 173 - 1.493 1.395 -0.337
ENSG00000106462 E014 24.1415452 0.0056808074 2.363321e-01 5.254313e-01 7 148809071 148809155 85 - 1.437 1.362 -0.260
ENSG00000106462 E015 2.9957591 0.0120798124 4.344355e-02 2.033516e-01 7 148809156 148809309 154 - 0.415 0.703 1.340
ENSG00000106462 E016 24.9516747 0.0058069089 9.638252e-01 9.923511e-01 7 148809310 148809390 81 - 1.411 1.411 -0.003
ENSG00000106462 E017 5.1703006 0.0248629875 4.815333e-06 1.825089e-04 7 148809391 148810199 809 - 0.315 0.969 2.965
ENSG00000106462 E018 1.0065518 0.0137479713 4.738752e-02 2.139281e-01 7 148810200 148810332 133 - 0.103 0.411 2.563
ENSG00000106462 E019 18.6579628 0.0007528673 6.545412e-01 8.550239e-01 7 148810333 148810414 82 - 1.305 1.278 -0.093
ENSG00000106462 E020 15.8964027 0.0031203063 4.123309e-01 6.936353e-01 7 148811625 148811720 96 - 1.187 1.252 0.229
ENSG00000106462 E021 0.1271363 0.0124382211 6.411386e-01   7 148811721 148811823 103 - 0.000 0.088 11.876
ENSG00000106462 E022 23.5986637 0.0006573828 8.278074e-01 9.377197e-01 7 148813959 148814137 179 - 1.379 1.395 0.057
ENSG00000106462 E023 9.9063853 0.0015491235 1.970000e-07 1.077586e-05 7 148814138 148814913 776 - 0.675 1.194 1.970
ENSG00000106462 E024 17.6893356 0.0007864619 9.496525e-01 9.868891e-01 7 148814914 148815039 126 - 1.269 1.268 -0.004
ENSG00000106462 E025 3.3767591 0.0372234499 2.298783e-02 1.383117e-01 7 148815040 148815505 466 - 0.415 0.758 1.563
ENSG00000106462 E026 12.0676857 0.0011879526 5.881172e-01 8.171847e-01 7 148815506 148815546 41 - 1.086 1.133 0.170
ENSG00000106462 E027 6.1493998 0.0044798145 8.263842e-01 9.371364e-01 7 148815547 148815954 408 - 0.836 0.863 0.103
ENSG00000106462 E028 5.1790748 0.0026260309 5.091823e-01 7.671660e-01 7 148815955 148816683 729 - 0.743 0.821 0.312
ENSG00000106462 E029 18.4735098 0.0036203964 4.006569e-01 6.840032e-01 7 148816684 148816778 95 - 1.250 1.313 0.221
ENSG00000106462 E030 11.0857941 0.0015493044 3.219204e-04 6.163455e-03 7 148816779 148817221 443 - 0.869 1.194 1.193
ENSG00000106462 E031 22.0923010 0.0044070281 7.822539e-01 9.162458e-01 7 148817222 148817356 135 - 1.369 1.354 -0.052
ENSG00000106462 E032 10.4711119 0.0013667695 5.506769e-01 7.948458e-01 7 148817357 148817391 35 - 1.025 1.080 0.200
ENSG00000106462 E033 2.1304810 0.0066875185 1.619753e-02 1.105820e-01 7 148817392 148817412 21 - 0.255 0.618 1.978
ENSG00000106462 E034 8.8171539 0.0121139328 2.087476e-02 1.302034e-01 7 148817413 148817876 464 - 0.836 1.080 0.910
ENSG00000106462 E035 17.3171166 0.0008197592 8.989484e-01 9.668737e-01 7 148817877 148818036 160 - 1.263 1.257 -0.019
ENSG00000106462 E036 9.4679255 0.0320751246 8.090997e-01 9.295555e-01 7 148818037 148818117 81 - 1.003 1.028 0.094
ENSG00000106462 E037 0.9864086 0.0842968077 6.733540e-01 8.647651e-01 7 148818118 148818504 387 - 0.255 0.327 0.493
ENSG00000106462 E038 1.3401880 0.3294129770 6.218891e-01 8.369955e-01 7 148818863 148818977 115 - 0.414 0.327 -0.505
ENSG00000106462 E039 1.9651976 0.0077735818 8.854747e-01 9.614703e-01 7 148818978 148819059 82 - 0.457 0.481 0.118
ENSG00000106462 E040 2.3564272 0.0477420248 2.626786e-01 5.554469e-01 7 148819060 148819595 536 - 0.415 0.594 0.871
ENSG00000106462 E041 12.7306610 0.0018438840 2.757682e-01 5.692686e-01 7 148819596 148819687 92 - 1.180 1.096 -0.300
ENSG00000106462 E042 4.3971053 0.0035331360 8.893710e-05 2.157775e-03 7 148819688 148820869 1182 - 0.368 0.889 2.340
ENSG00000106462 E043 0.3811266 0.0362500700 1.451688e-01   7 148826454 148826468 15 - 0.000 0.224 13.461
ENSG00000106462 E044 21.1344763 0.0012394227 6.423389e-02 2.552413e-01 7 148826469 148826632 164 - 1.402 1.289 -0.395
ENSG00000106462 E045 18.5471392 0.0059241111 3.782713e-02 1.876880e-01 7 148827164 148827266 103 - 1.364 1.218 -0.511
ENSG00000106462 E046 21.8152764 0.0239004700 4.549578e-01 7.276598e-01 7 148828740 148828880 141 - 1.388 1.327 -0.213
ENSG00000106462 E047 12.7822562 0.0010914679 9.373571e-01 9.820871e-01 7 148829728 148829848 121 - 1.131 1.140 0.034
ENSG00000106462 E048 11.8437302 0.0012626759 7.438102e-02 2.780918e-01 7 148832634 148832750 117 - 1.180 1.037 -0.513
ENSG00000106462 E049 2.6697568 0.0426643289 1.292399e-01 3.813977e-01 7 148836822 148837000 179 - 0.675 0.447 -1.052
ENSG00000106462 E050 6.3037411 0.0026119546 4.437253e-03 4.557586e-02 7 148846470 148846496 27 - 1.003 0.703 -1.162
ENSG00000106462 E051 8.4926000 0.0026835353 1.904656e-03 2.465386e-02 7 148846497 148846598 102 - 1.114 0.821 -1.093
ENSG00000106462 E052 6.5674438 0.0049423471 4.911500e-02 2.185437e-01 7 148847182 148847305 124 - 0.979 0.774 -0.785
ENSG00000106462 E053 0.1268540 0.0123048460 6.413249e-01   7 148870804 148871367 564 - 0.000 0.088 11.876
ENSG00000106462 E054 0.0000000       7 148883197 148883261 65 -      
ENSG00000106462 E055 0.0000000       7 148883262 148883509 248 -      
ENSG00000106462 E056 0.0000000       7 148884060 148884163 104 -      
ENSG00000106462 E057 3.4457754 0.0041223009 7.752409e-01 9.136804e-01 7 148884164 148884321 158 - 0.623 0.663 0.170

Help

Please Click HERE to learn more details about the results from DEXseq.