ENSG00000106638

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000305632 ENSG00000106638 No_inf pgKDN_inf TBL2 protein_coding protein_coding 25.30001 17.20251 28.98734 0.8259591 0.5164225 0.7524633 3.0776366 1.7205908 3.7605354 0.1486849 0.2763567 1.1235048 0.11985000 0.101000 0.130300 0.02930 0.85209425 0.03621529 FALSE  
ENST00000435792 ENSG00000106638 No_inf pgKDN_inf TBL2 protein_coding nonsense_mediated_decay 25.30001 17.20251 28.98734 0.8259591 0.5164225 0.7524633 0.5078534 1.0079690 0.1064621 0.1346966 0.1064621 -3.1277610 0.02474167 0.058425 0.003625 -0.05480 0.03621529 0.03621529 FALSE  
ENST00000437521 ENSG00000106638 No_inf pgKDN_inf TBL2 protein_coding nonsense_mediated_decay 25.30001 17.20251 28.98734 0.8259591 0.5164225 0.7524633 0.3339704 0.8250781 0.0000000 0.4876770 0.0000000 -6.3838392 0.01890000 0.051550 0.000000 -0.05155 0.41457226 0.03621529 FALSE  
ENST00000450285 ENSG00000106638 No_inf pgKDN_inf TBL2 protein_coding nonsense_mediated_decay 25.30001 17.20251 28.98734 0.8259591 0.5164225 0.7524633 13.8741848 8.8680006 16.8875450 1.5439213 2.3933270 0.9285069 0.54879167 0.524250 0.586950 0.06270 0.88950802 0.03621529 FALSE  
MSTRG.26318.2 ENSG00000106638 No_inf pgKDN_inf TBL2 protein_coding   25.30001 17.20251 28.98734 0.8259591 0.5164225 0.7524633 3.4612240 2.1980979 5.2640359 1.5885277 3.5497333 1.2561033 0.13200000 0.121175 0.175525 0.05435 1.00000000 0.03621529 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106638 E001 24.3279359 0.0006419399 6.834619e-01 0.8689902504 7 73567537 73569659 2123 - 1.394 1.379 -0.051
ENSG00000106638 E002 46.3396792 0.0003146570 5.218676e-01 0.7755754088 7 73569660 73570007 348 - 1.646 1.683 0.128
ENSG00000106638 E003 38.8744955 0.0003874650 2.352770e-01 0.5245299628 7 73570008 73570194 187 - 1.560 1.626 0.224
ENSG00000106638 E004 41.1856724 0.0003478988 1.932029e-01 0.4730221794 7 73570195 73570410 216 - 1.583 1.652 0.236
ENSG00000106638 E005 13.8571823 0.0011613808 4.543872e-02 0.2084856431 7 73570411 73570470 60 - 1.208 1.053 -0.553
ENSG00000106638 E006 42.6762475 0.0003863625 7.782355e-01 0.9148664358 7 73570471 73570885 415 - 1.616 1.639 0.077
ENSG00000106638 E007 20.2367020 0.0007201777 9.241879e-01 0.9769512019 7 73570886 73570972 87 - 1.311 1.314 0.013
ENSG00000106638 E008 24.2826040 0.0005947886 4.865400e-01 0.7501242050 7 73571189 73571341 153 - 1.368 1.420 0.179
ENSG00000106638 E009 0.4982566 0.0154664508 1.140670e-01   7 73571342 73571394 53 - 0.072 0.301 2.470
ENSG00000106638 E010 1.4519974 0.0103605695 8.681790e-01 0.9548063430 7 73571584 73571981 398 - 0.388 0.367 -0.115
ENSG00000106638 E011 0.4879983 0.1360182634 5.707488e-01   7 73571982 73572035 54 - 0.134 0.221 0.886
ENSG00000106638 E012 5.3389892 0.0062973258 6.945681e-01 0.8752285361 7 73572844 73572847 4 - 0.768 0.823 0.217
ENSG00000106638 E013 7.3859763 0.0105888692 9.658091e-01 0.9929839238 7 73572848 73572877 30 - 0.904 0.920 0.059
ENSG00000106638 E014 12.6933699 0.0013556703 6.120437e-01 0.8312130636 7 73572878 73572970 93 - 1.134 1.102 -0.115
ENSG00000106638 E015 0.2357071 0.0157719268 5.231419e-01   7 73572971 73573319 349 - 0.134 0.000 -14.367
ENSG00000106638 E016 4.9351404 0.0027881002 2.289722e-01 0.5177072585 7 73573320 73573320 1 - 0.806 0.668 -0.563
ENSG00000106638 E017 6.0150033 0.0023739891 1.451194e-01 0.4054578065 7 73573321 73573340 20 - 0.884 0.726 -0.624
ENSG00000106638 E018 5.2803166 0.0029966395 6.527108e-02 0.2571982284 7 73573341 73573342 2 - 0.853 0.636 -0.881
ENSG00000106638 E019 7.9486594 0.0021314849 1.480552e-01 0.4097058424 7 73573343 73573400 58 - 0.984 0.844 -0.530
ENSG00000106638 E020 7.7309988 0.0023836000 3.144431e-01 0.6074598848 7 73573401 73573471 71 - 0.959 0.864 -0.359
ENSG00000106638 E021 0.5077596 0.0150782228 9.711860e-03 0.0788349982 7 73573832 73573878 47 - 0.000 0.367 15.853
ENSG00000106638 E022 0.1268540 0.0124210997 2.873613e-01   7 73573879 73573937 59 - 0.000 0.125 13.982
ENSG00000106638 E023 5.7622518 0.0374253867 5.877089e-02 0.2430416640 7 73573938 73573960 23 - 0.895 0.636 -1.042
ENSG00000106638 E024 13.0405330 0.0016436729 1.849415e-01 0.4624706096 7 73573961 73574055 95 - 1.167 1.066 -0.363
ENSG00000106638 E025 11.3770706 0.0012674225 7.407366e-01 0.8971486014 7 73574056 73574122 67 - 1.085 1.066 -0.069
ENSG00000106638 E026 11.5866216 0.0011414247 2.562015e-01 0.5482761836 7 73574383 73574444 62 - 1.116 1.027 -0.323
ENSG00000106638 E027 10.4770748 0.0013430933 1.074594e-01 0.3436126356 7 73574445 73574476 32 - 1.092 0.953 -0.508
ENSG00000106638 E028 10.2935171 0.0013554477 9.402653e-01 0.9830356734 7 73574477 73574513 37 - 1.038 1.041 0.010
ENSG00000106638 E029 0.5075387 0.0249100029 1.019209e-02 0.0812939049 7 73574514 73574571 58 - 0.000 0.367 15.811
ENSG00000106638 E030 1.7695914 0.0078131110 7.570082e-06 0.0002685224 7 73574572 73574804 233 - 0.072 0.726 4.585
ENSG00000106638 E031 1.8569815 0.0706681367 3.016878e-02 0.1633598264 7 73576541 73576701 161 - 0.279 0.636 1.885
ENSG00000106638 E032 0.5083889 0.0167271262 9.722882e-03 0.0788799513 7 73576702 73576748 47 - 0.000 0.367 15.846
ENSG00000106638 E033 1.3871126 0.0277073469 2.010605e-04 0.0042047299 7 73577973 73578245 273 - 0.072 0.636 4.207
ENSG00000106638 E034 0.3817870 0.5297884738 1.385167e-01   7 73578246 73578267 22 - 0.000 0.301 14.282
ENSG00000106638 E035 0.3817870 0.5297884738 1.385167e-01   7 73578268 73578284 17 - 0.000 0.301 14.282
ENSG00000106638 E036 0.2545247 0.2460079450 1.342037e-01   7 73578285 73578289 5 - 0.000 0.222 14.222
ENSG00000106638 E037 0.3810317 0.0220602857 3.111618e-02   7 73578290 73578419 130 - 0.000 0.301 15.442
ENSG00000106638 E038 10.6378634 0.0142962047 5.087780e-01 0.7669435184 7 73578420 73578676 257 - 1.072 1.013 -0.215
ENSG00000106638 E039 0.0000000       7 73578743 73578791 49 -      

Help

Please Click HERE to learn more details about the results from DEXseq.