ENSG00000106733

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361092 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding protein_coding 11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 0.8125309 0.0000000 2.4375927 0.00000000 1.6173644 7.9352197 0.06303333 0.000000 0.189100 0.189100 0.5351066314 0.0002287669 FALSE TRUE
ENST00000376808 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding protein_coding 11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 5.5221738 4.4305398 6.2554432 1.66741437 1.2808052 0.4966815 0.44877500 0.362050 0.470100 0.108050 0.8484441395 0.0002287669 FALSE TRUE
ENST00000376811 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding protein_coding 11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 2.7408344 2.6735132 2.0293050 0.69879551 0.8383558 -0.3960455 0.24623333 0.261175 0.148000 -0.113175 0.8010885117 0.0002287669 FALSE TRUE
ENST00000482537 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding protein_coding_CDS_not_defined 11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 0.6672050 1.4852303 0.1178666 0.07277506 0.1178666 -3.5476562 0.06234167 0.137375 0.008900 -0.128475 0.0187234314 0.0002287669   FALSE
ENST00000490321 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding protein_coding_CDS_not_defined 11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 0.9204110 0.2297095 1.3300065 0.22970951 0.5467618 2.4828809 0.07102500 0.020225 0.098575 0.078350 0.4930223874 0.0002287669   FALSE
MSTRG.28845.3 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding   11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 0.5805088 1.6515681 0.0000000 0.09497443 0.0000000 -7.3764016 0.05521667 0.153950 0.000000 -0.153950 0.0002287669 0.0002287669 FALSE TRUE
MSTRG.28845.4 ENSG00000106733 No_inf pgKDN_inf NMRK1 protein_coding   11.8787 11.17221 13.28606 1.137577 0.510832 0.2497932 0.2985194 0.1089820 0.7865761 0.10898195 0.4581418 2.7430695 0.02329167 0.007800 0.062075 0.054275 0.7958361647 0.0002287669 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106733 E001 0.0000000       9 75060573 75060576 4 -      
ENSG00000106733 E002 0.0000000       9 75060577 75060682 106 -      
ENSG00000106733 E003 0.8534156 0.025653210 0.798372326 0.92419288 9 75060683 75060747 65 - 0.287 0.247 -0.287
ENSG00000106733 E004 5.6124635 0.039271261 0.810024099 0.92988498 9 75060748 75061199 452 - 0.836 0.804 -0.124
ENSG00000106733 E005 0.7420822 0.016504321 0.357498157 0.64713226 9 75061200 75061201 2 - 0.167 0.306 1.128
ENSG00000106733 E006 20.4037348 0.004893203 0.068443179 0.26403079 9 75061202 75061567 366 - 1.269 1.385 0.407
ENSG00000106733 E007 10.3792494 0.001323509 0.712192662 0.88377203 9 75066757 75066840 84 - 1.071 1.041 -0.110
ENSG00000106733 E008 1.2617667 0.011410446 0.004818767 0.04823851 9 75066841 75067205 365 - 0.091 0.519 3.298
ENSG00000106733 E009 10.5860826 0.001924986 0.213563060 0.49873848 9 75068996 75069102 107 - 1.112 1.009 -0.374
ENSG00000106733 E010 0.6082371 0.159569153 0.721189110 0.88767064 9 75069103 75069122 20 - 0.231 0.180 -0.457
ENSG00000106733 E011 0.4993265 0.016164519 0.277568907   9 75069123 75069741 619 - 0.091 0.247 1.713
ENSG00000106733 E012 9.1345621 0.001922227 0.357332370 0.64698416 9 75069742 75069813 72 - 1.044 0.963 -0.298
ENSG00000106733 E013 0.4791531 0.020649758 0.365735831   9 75069814 75069894 81 - 0.231 0.099 -1.457
ENSG00000106733 E014 12.3736911 0.002224649 0.724693030 0.88940307 9 75069895 75070042 148 - 1.112 1.140 0.100
ENSG00000106733 E015 8.3324847 0.001779750 0.714332001 0.88491888 9 75077159 75077207 49 - 0.952 0.987 0.128
ENSG00000106733 E016 11.6260255 0.001774971 0.737712436 0.89590776 9 75077490 75077580 91 - 1.088 1.115 0.098
ENSG00000106733 E017 6.2712218 0.006403350 0.203061713 0.48565165 9 75078326 75078582 257 - 0.789 0.925 0.527
ENSG00000106733 E018 0.3715287 0.315360681 0.586906086   9 75082709 75083086 378 - 0.091 0.180 1.130
ENSG00000106733 E019 5.6894997 0.002601190 0.053741385 0.23070297 9 75083087 75083150 64 - 0.917 0.707 -0.826
ENSG00000106733 E020 0.2362687 0.015925231 0.275824421   9 75087544 75087650 107 - 0.167 0.000 -9.325
ENSG00000106733 E021 2.0958568 0.009804486 0.364925652 0.65335923 9 75087651 75087868 218 - 0.421 0.551 0.643
ENSG00000106733 E022 7.2483626 0.010825756 0.029512570 0.16139428 9 75088008 75088217 210 - 1.015 0.787 -0.872

Help

Please Click HERE to learn more details about the results from DEXseq.