ENSG00000106771

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374586 ENSG00000106771 No_inf pgKDN_inf TMEM245 protein_coding protein_coding 15.47065 11.96792 18.48232 0.3579765 0.8525139 0.6265495 1.913025 1.916258 3.822816 1.916258 3.8228161 0.9926042 0.11793333 0.169475 0.184325 0.014850 1.000000000 0.000155229 FALSE TRUE
ENST00000413712 ENSG00000106771 No_inf pgKDN_inf TMEM245 protein_coding protein_coding 15.47065 11.96792 18.48232 0.3579765 0.8525139 0.6265495 1.060454 0.000000 3.181362 0.000000 0.7670058 8.3180286 0.05589167 0.000000 0.167675 0.167675 0.000155229 0.000155229 FALSE TRUE
MSTRG.29142.2 ENSG00000106771 No_inf pgKDN_inf TMEM245 protein_coding   15.47065 11.96792 18.48232 0.3579765 0.8525139 0.6265495 12.072566 9.515477 11.328921 2.060610 3.7777815 0.2514200 0.79696667 0.786300 0.640200 -0.146100 0.825907490 0.000155229 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106771 E001 0.0000000       9 109015135 109015151 17 -      
ENSG00000106771 E002 300.8051360 0.0002731083 5.435201e-06 0.0002020277 9 109015152 109018925 3774 - 2.449 2.510 0.204
ENSG00000106771 E003 75.6847588 0.0016219815 1.216674e-01 0.3692517055 9 109018926 109019903 978 - 1.856 1.913 0.192
ENSG00000106771 E004 18.6293871 0.0006966657 1.128608e-01 0.3534454205 9 109019904 109020087 184 - 1.239 1.346 0.375
ENSG00000106771 E005 37.2050507 0.0004926045 9.999974e-01 1.0000000000 9 109020088 109020505 418 - 1.581 1.582 0.005
ENSG00000106771 E006 27.4302282 0.0082851909 9.876201e-01 0.9998311377 9 109033307 109033501 195 - 1.453 1.454 0.004
ENSG00000106771 E007 0.1272623 0.0123053599 4.381134e-01   9 109036020 109036205 186 - 0.000 0.104 9.023
ENSG00000106771 E008 17.3328937 0.0026416207 6.573624e-02 0.2582618366 9 109036206 109036380 175 - 1.319 1.187 -0.464
ENSG00000106771 E009 12.7183130 0.0011756836 4.500651e-02 0.2073798614 9 109038017 109038117 101 - 1.204 1.043 -0.579
ENSG00000106771 E010 2.1220416 0.0065983441 8.794770e-03 0.0737349813 9 109038118 109039327 1210 - 0.275 0.656 2.000
ENSG00000106771 E011 18.0452919 0.0007894861 2.050311e-02 0.1289128721 9 109050283 109050428 146 - 1.346 1.187 -0.558
ENSG00000106771 E012 19.6351337 0.0007135707 1.824132e-02 0.1192855175 9 109050570 109050692 123 - 1.379 1.224 -0.543
ENSG00000106771 E013 17.1039964 0.0008914015 5.329713e-02 0.2297967544 9 109057191 109057322 132 - 1.315 1.180 -0.476
ENSG00000106771 E014 6.9454702 0.0054804381 8.786259e-01 0.9589180087 9 109060354 109060452 99 - 0.906 0.891 -0.057
ENSG00000106771 E015 6.8792496 0.0109543424 5.426543e-02 0.2319505355 9 109064477 109064567 91 - 0.982 0.770 -0.816
ENSG00000106771 E016 0.0000000       9 109073248 109073355 108 -      
ENSG00000106771 E017 7.0919859 0.0021387405 2.144898e-03 0.0269217913 9 109073356 109073438 83 - 1.030 0.705 -1.253
ENSG00000106771 E018 7.6287414 0.0018785086 1.096058e-01 0.3474888632 9 109080839 109080943 105 - 1.002 0.843 -0.599
ENSG00000106771 E019 0.0000000       9 109085997 109086020 24 -      
ENSG00000106771 E020 10.2527454 0.0116720046 8.840823e-01 0.9610440074 9 109087173 109087342 170 - 1.056 1.043 -0.046
ENSG00000106771 E021 10.4404182 0.0093823779 2.559610e-01 0.5480024341 9 109090922 109091155 234 - 1.104 0.998 -0.384
ENSG00000106771 E022 7.9121497 0.0017171905 5.847033e-01 0.8153960404 9 109093475 109093591 117 - 0.972 0.921 -0.194
ENSG00000106771 E023 6.8985112 0.0020694773 7.749166e-02 0.2848384986 9 109106508 109106609 102 - 0.972 0.790 -0.701
ENSG00000106771 E024 5.8340310 0.0025879075 4.607512e-01 0.7319790207 9 109108453 109108570 118 - 0.869 0.790 -0.311
ENSG00000106771 E025 10.9647424 0.0122296877 4.408931e-03 0.0454146788 9 109119335 109119961 627 - 1.186 0.906 -1.022

Help

Please Click HERE to learn more details about the results from DEXseq.