ENSG00000106799

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374990 ENSG00000106799 No_inf pgKDN_inf TGFBR1 protein_coding protein_coding 35.71923 25.8564 40.18377 0.4646048 0.5465577 0.6358926 11.111434 7.558639 15.04776 2.541703 1.959839 0.9924014 0.30691667 0.287500 0.372825 0.085325 8.405931e-01 6.206709e-13 FALSE TRUE
ENST00000374994 ENSG00000106799 No_inf pgKDN_inf TGFBR1 protein_coding protein_coding 35.71923 25.8564 40.18377 0.4646048 0.5465577 0.6358926 18.330380 7.269039 22.85978 3.174468 1.514172 1.6516224 0.48794167 0.287775 0.570700 0.282925 4.707409e-01 6.206709e-13 FALSE TRUE
MSTRG.29093.11 ENSG00000106799 No_inf pgKDN_inf TGFBR1 protein_coding   35.71923 25.8564 40.18377 0.4646048 0.5465577 0.6358926 2.073349 6.220046 0.00000 0.536789 0.000000 -9.2830991 0.07990833 0.239725 0.000000 -0.239725 6.206709e-13 6.206709e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000106799 E001 0.0000000       9 99104038 99104069 32 +      
ENSG00000106799 E002 0.0000000       9 99104070 99104106 37 +      
ENSG00000106799 E003 0.3732278 0.2498552791 4.567260e-01   9 99105037 99105110 74 + 0.082 0.199 1.488
ENSG00000106799 E004 0.3816610 0.0358536388 5.472296e-02   9 99105111 99105112 2 + 0.000 0.272 13.677
ENSG00000106799 E005 0.3812526 0.0158565799 5.282876e-02   9 99105113 99105125 13 + 0.000 0.272 13.829
ENSG00000106799 E006 2.6816920 0.0053892634 7.204537e-01 8.874416e-01 9 99105126 99105149 24 + 0.542 0.591 0.225
ENSG00000106799 E007 11.9823121 0.0011785941 9.294169e-02 3.167153e-01 9 99105150 99105302 153 + 1.166 1.024 -0.512
ENSG00000106799 E008 0.6351783 0.0308602000 8.004561e-03 6.916614e-02 9 99127775 99127873 99 + 0.000 0.389 14.421
ENSG00000106799 E009 0.1265070 0.0122904242 3.805142e-01   9 99127874 99127915 42 + 0.000 0.111 12.311
ENSG00000106799 E010 0.1265070 0.0122904242 3.805142e-01   9 99127916 99127933 18 + 0.000 0.111 12.311
ENSG00000106799 E011 0.2536433 0.0160133146 1.468081e-01   9 99127934 99128002 69 + 0.000 0.199 13.256
ENSG00000106799 E012 0.3806233 0.0158783992 5.280744e-02   9 99128836 99128854 19 + 0.000 0.272 13.829
ENSG00000106799 E013 8.0989952 0.0020988618 8.681689e-02 3.054392e-01 9 99128855 99128905 51 + 1.022 0.850 -0.643
ENSG00000106799 E014 20.2021300 0.0008484075 1.419869e-02 1.012417e-01 9 99128906 99129100 195 + 1.387 1.221 -0.577
ENSG00000106799 E015 0.6252643 0.0148349775 8.373808e-02 2.984622e-01 9 99130040 99130195 156 + 0.082 0.334 2.488
ENSG00000106799 E016 0.8592722 0.0158279056 4.160506e-01 6.960013e-01 9 99132497 99132508 12 + 0.210 0.334 0.903
ENSG00000106799 E017 22.7301552 0.0008190673 6.752454e-01 8.654631e-01 9 99132509 99132739 231 + 1.383 1.357 -0.091
ENSG00000106799 E018 30.8464339 0.0004576841 2.643452e-01 5.573789e-01 9 99137859 99138089 231 + 1.524 1.464 -0.207
ENSG00000106799 E019 27.0983936 0.0084541511 1.915664e-02 1.234992e-01 9 99142536 99142703 168 + 1.508 1.346 -0.561
ENSG00000106799 E020 30.1820560 0.0237398230 2.186117e-01 5.052206e-01 9 99144732 99144888 157 + 1.535 1.423 -0.384
ENSG00000106799 E021 0.5985465 0.0529807212 3.293389e-01 6.217284e-01 9 99145497 99145612 116 + 0.262 0.111 -1.512
ENSG00000106799 E022 27.5979304 0.0122285624 9.847822e-02 3.274351e-01 9 99146485 99146609 125 + 1.502 1.378 -0.427
ENSG00000106799 E023 0.8518064 0.1882739629 9.206317e-01 9.752146e-01 9 99146832 99147653 822 + 0.262 0.272 0.073
ENSG00000106799 E024 24.0142174 0.0005716618 2.231591e-01 5.106649e-01 9 99147654 99147784 131 + 1.425 1.351 -0.257
ENSG00000106799 E025 911.8400610 0.0000702002 2.190944e-06 9.174409e-05 9 99149180 99154192 5013 + 2.947 2.968 0.070

Help

Please Click HERE to learn more details about the results from DEXseq.