ENSG00000107140

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336395 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding protein_coding 33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 10.120391 4.003764 10.402068 1.0706497 4.5125554 1.3752290 0.28487500 0.171175 0.333975 0.162800 0.85128937 0.02013967 FALSE TRUE
ENST00000463897 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding protein_coding_CDS_not_defined 33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 3.530648 4.083731 2.083809 0.6737429 0.7529507 -0.9672867 0.11220000 0.173800 0.067200 -0.106600 0.43455739 0.02013967   FALSE
ENST00000480077 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding protein_coding_CDS_not_defined 33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 2.648300 1.836509 3.306145 0.4236880 1.3745599 0.8447066 0.08223333 0.078100 0.109125 0.031025 0.96095240 0.02013967 FALSE TRUE
ENST00000498522 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding protein_coding_CDS_not_defined 33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 3.889343 8.077956 2.092949 1.1483396 2.0929486 -1.9433615 0.14654167 0.344575 0.064900 -0.279675 0.02013967 0.02013967 FALSE TRUE
ENST00000620767 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding protein_coding 33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 5.297905 0.000000 7.614695 0.0000000 4.6239730 9.5745359 0.14921667 0.000000 0.267400 0.267400 0.80275017 0.02013967 FALSE TRUE
MSTRG.28670.3 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding   33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 3.323496 3.267266 1.353988 0.3080263 0.2066807 -1.2646621 0.10066667 0.140150 0.044650 -0.095500 0.12211392 0.02013967 FALSE TRUE
MSTRG.28670.6 ENSG00000107140 No_inf pgKDN_inf TESK1 protein_coding   33.22189 23.3042 30.19377 0.8953088 0.9793271 0.3735194 4.411808 2.034977 3.340114 1.3143565 1.9332929 0.7121255 0.12424167 0.092175 0.112750 0.020575 1.00000000 0.02013967 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000107140 E001 0.7246754 0.0141572550 5.840022e-01 8.150095e-01 9 35605262 35605304 43 + 0.273 0.190 -0.669
ENSG00000107140 E002 1.0878631 0.0107399377 5.026651e-01 7.622690e-01 9 35605305 35605322 18 + 0.364 0.261 -0.670
ENSG00000107140 E003 2.7663792 0.0055426159 7.247412e-02 2.732046e-01 9 35605323 35605425 103 + 0.673 0.423 -1.172
ENSG00000107140 E004 3.4125700 0.0756972703 9.835773e-01 9.986903e-01 9 35605426 35605473 48 + 0.653 0.633 -0.085
ENSG00000107140 E005 3.0506965 0.0978131685 9.031524e-01 9.688647e-01 9 35605474 35605490 17 + 0.608 0.604 -0.018
ENSG00000107140 E006 19.1236941 0.0102950568 5.164488e-01 7.721923e-01 9 35605491 35605838 348 + 1.324 1.275 -0.171
ENSG00000107140 E007 16.7534196 0.0014772259 4.736817e-01 7.406804e-01 9 35605984 35606105 122 + 1.223 1.275 0.183
ENSG00000107140 E008 8.1619606 0.0018586996 6.683288e-01 8.619436e-01 9 35606237 35606285 49 + 0.978 0.939 -0.148
ENSG00000107140 E009 16.2675732 0.0010162160 9.506885e-02 3.208864e-01 9 35606837 35606971 135 + 1.286 1.168 -0.418
ENSG00000107140 E010 6.2338925 0.0023152891 7.025547e-01 8.790058e-01 9 35606972 35606983 12 + 0.838 0.880 0.160
ENSG00000107140 E011 3.8980236 0.0036341556 8.023665e-07 3.819491e-05 9 35606984 35607193 210 + 0.273 0.925 3.085
ENSG00000107140 E012 1.8610673 0.0078746265 8.589076e-02 3.034278e-01 9 35607194 35607224 31 + 0.320 0.573 1.330
ENSG00000107140 E013 3.9442436 0.0039379387 9.206245e-02 3.151220e-01 9 35607225 35607326 102 + 0.584 0.793 0.878
ENSG00000107140 E014 13.4491878 0.0080472934 6.671045e-02 2.602035e-01 9 35607327 35607409 83 + 1.223 1.068 -0.554
ENSG00000107140 E015 4.2172185 0.0039362152 6.819044e-03 6.199904e-02 9 35607410 35607581 172 + 0.532 0.864 1.394
ENSG00000107140 E016 19.8337525 0.0013153157 3.907141e-01 6.761266e-01 9 35607582 35607665 84 + 1.342 1.288 -0.189
ENSG00000107140 E017 13.0739722 0.0113274352 7.047756e-01 8.800487e-01 9 35607666 35607672 7 + 1.128 1.168 0.141
ENSG00000107140 E018 2.1941708 0.0062170433 9.951220e-01 1.000000e+00 9 35607673 35607927 255 + 0.503 0.505 0.008
ENSG00000107140 E019 22.9095082 0.0062966462 7.024254e-01 8.789720e-01 9 35607928 35608011 84 + 1.387 1.366 -0.071
ENSG00000107140 E020 24.6693993 0.0005863704 5.298251e-01 7.811814e-01 9 35608160 35608249 90 + 1.390 1.428 0.130
ENSG00000107140 E021 0.0000000       9 35608250 35608282 33 +      
ENSG00000107140 E022 30.7315449 0.0099459105 8.953038e-01 9.654180e-01 9 35608395 35608509 115 + 1.496 1.505 0.032
ENSG00000107140 E023 42.8477767 0.0003721125 3.505236e-01 6.407580e-01 9 35608862 35609106 245 + 1.658 1.619 -0.133
ENSG00000107140 E024 96.2901415 0.0030330921 6.550110e-01 8.553009e-01 9 35609107 35610041 935 + 1.980 1.994 0.048

Help

Please Click HERE to learn more details about the results from DEXseq.