ENSG00000107175

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000353704 ENSG00000107175 No_inf pgKDN_inf CREB3 protein_coding protein_coding 41.66728 23.23006 51.96593 1.354715 0.6144603 1.16123 25.18303 9.649333 36.16263 1.0212576 1.897720 1.9049032 0.5680583 0.413425 0.69525 0.281825 0.001244884 0.001244884 FALSE TRUE
ENST00000486056 ENSG00000107175 No_inf pgKDN_inf CREB3 protein_coding protein_coding_CDS_not_defined 41.66728 23.23006 51.96593 1.354715 0.6144603 1.16123 16.48425 13.580727 15.80329 0.7743838 1.511866 0.2185152 0.4319417 0.586575 0.30475 -0.281825 0.003972343 0.001244884 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000107175 E001 9.6768300 0.0015693886 0.002995503 0.03449286 9 35732598 35732665 68 + 0.898 1.163 0.974
ENSG00000107175 E002 46.5585484 0.0003139075 0.301039636 0.59408239 9 35732666 35732901 236 + 1.643 1.688 0.152
ENSG00000107175 E003 37.1296012 0.0003836788 0.034192100 0.17640485 9 35732996 35733143 148 + 1.599 1.493 -0.362
ENSG00000107175 E004 0.6176177 0.0159437668 0.246307985 0.53698108 9 35733144 35733214 71 + 0.132 0.305 1.522
ENSG00000107175 E005 25.6386266 0.0006381327 0.015395038 0.10701327 9 35733215 35733282 68 + 1.456 1.308 -0.515
ENSG00000107175 E006 28.7320324 0.0084214640 0.483670272 0.74812218 9 35733396 35733485 90 + 1.440 1.484 0.152
ENSG00000107175 E007 41.9327257 0.0005437185 0.395981235 0.68086147 9 35735109 35735215 107 + 1.601 1.640 0.133
ENSG00000107175 E008 36.1739758 0.0004073947 0.834556336 0.94035591 9 35735306 35735374 69 + 1.557 1.547 -0.034
ENSG00000107175 E009 42.6453414 0.0003379984 0.711701437 0.88347977 9 35736048 35736132 85 + 1.616 1.633 0.059
ENSG00000107175 E010 36.1752781 0.0020824928 0.743655432 0.89860560 9 35736227 35736311 85 + 1.559 1.542 -0.055
ENSG00000107175 E011 74.4557132 0.0029774670 0.856058554 0.94938303 9 35736392 35736999 608 + 1.862 1.856 -0.021

Help

Please Click HERE to learn more details about the results from DEXseq.