ENSG00000107290

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000224140 ENSG00000107290 No_inf pgKDN_inf SETX protein_coding protein_coding 19.85391 24.27938 18.06835 1.629029 0.5782041 -0.4260627 6.873091 6.412518 7.342835 0.1434867 0.7373041 0.19516162 0.3584417 0.266925 0.408200 0.141275 0.463067950612 0.000002625277 FALSE TRUE
ENST00000436441 ENSG00000107290 No_inf pgKDN_inf SETX protein_coding protein_coding 19.85391 24.27938 18.06835 1.629029 0.5782041 -0.4260627 7.548359 8.138924 7.607993 0.5682118 0.9452448 -0.09719859 0.3880250 0.343775 0.419150 0.075375 0.825139217056 0.000002625277 FALSE TRUE
ENST00000464133 ENSG00000107290 No_inf pgKDN_inf SETX protein_coding protein_coding_CDS_not_defined 19.85391 24.27938 18.06835 1.629029 0.5782041 -0.4260627 2.527085 3.883137 1.704849 1.2657956 0.4314871 -1.18285197 0.1206667 0.151625 0.094025 -0.057600 0.834678301423 0.000002625277 FALSE TRUE
ENST00000477049 ENSG00000107290 No_inf pgKDN_inf SETX protein_coding protein_coding_CDS_not_defined 19.85391 24.27938 18.06835 1.629029 0.5782041 -0.4260627 1.773365 4.077109 0.000000 0.7835729 0.0000000 -8.67493686 0.0783250 0.164675 0.000000 -0.164675 0.000002625277 0.000002625277 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000107290 E001 5.103734 0.0397291760 0.047537943897144427363166 0.214373868407072537545 9 132261356 132261542 187 - 0.615 0.885 1.095
ENSG00000107290 E002 334.518974 0.0000894249 0.000000000000000007185805 0.000000000000001621587 9 132261543 132264985 3443 - 2.457 2.571 0.380
ENSG00000107290 E003 1.513742 0.0984671928 0.009619809818062839690267 0.078362003130554469532 9 132266127 132266249 123 - 0.100 0.548 3.282
ENSG00000107290 E004 4.369350 0.1189469843 0.156741958625052191234062 0.423130326667178757738 9 132269403 132269489 87 - 0.845 0.601 -1.002
ENSG00000107290 E005 25.063909 0.0188384087 0.743512270583690515479702 0.898605599858971371141 9 132269615 132269702 88 - 1.402 1.424 0.077
ENSG00000107290 E006 31.687429 0.0005032765 0.162246660045002127903402 0.430680772189197758060 9 132271710 132271808 99 - 1.552 1.477 -0.256
ENSG00000107290 E007 3.749958 0.0057042540 0.008482858514401460034438 0.071891026259542481491 9 132274923 132275255 333 - 0.451 0.799 1.538
ENSG00000107290 E008 37.211617 0.0003916592 0.201611927304997634591288 0.484016078708539521092 9 132275256 132275420 165 - 1.614 1.550 -0.216
ENSG00000107290 E009 16.572753 0.0009123855 0.933003535744316159217249 0.980621175954649593187 9 132277060 132277152 93 - 1.241 1.245 0.015
ENSG00000107290 E010 24.308384 0.0011510387 0.986868294239266696799007 0.999547771027343268102 9 132278070 132278257 188 - 1.402 1.401 -0.003
ENSG00000107290 E011 15.770048 0.0097764828 0.320667030184170809281596 0.613575605986911298828 9 132281467 132281574 108 - 1.266 1.184 -0.290
ENSG00000107290 E012 1.878724 0.0074184169 0.030966838531588505856185 0.165724583059909308380 9 132282770 132283263 494 - 0.251 0.575 1.822
ENSG00000107290 E013 18.471364 0.0299540103 0.034540201316775917539381 0.177553490070433889203 9 132283264 132283413 150 - 1.388 1.184 -0.715
ENSG00000107290 E014 12.664862 0.0031270471 0.054552886960928970161433 0.232662929412521229944 9 132286423 132286494 72 - 1.214 1.055 -0.569
ENSG00000107290 E015 0.000000       9 132286495 132286497 3 -      
ENSG00000107290 E016 16.619303 0.0031320818 0.137230853002382024996564 0.394321194769870653207 9 132288236 132288351 116 - 1.301 1.190 -0.390
ENSG00000107290 E017 15.738372 0.0151415398 0.714163443442908940639313 0.884874248401062546421 9 132288550 132288651 102 - 1.207 1.233 0.093
ENSG00000107290 E018 16.436767 0.0013880115 0.867312221287334539354674 0.954294694661371400990 9 132295872 132296028 157 - 1.247 1.233 -0.049
ENSG00000107290 E019 15.693119 0.0117594192 0.657350548353864971851124 0.856614102515641073765 9 132296887 132297054 168 - 1.241 1.203 -0.133
ENSG00000107290 E020 20.713969 0.0012841161 0.591734634849501062170418 0.819584380995711070383 9 132298080 132298312 233 - 1.354 1.318 -0.127
ENSG00000107290 E021 18.000725 0.0009949581 0.336738464164309081461113 0.628757220918741421833 9 132300630 132300803 174 - 1.312 1.245 -0.237
ENSG00000107290 E022 13.316835 0.0010671742 0.199014072448529089065516 0.480541211237492271735 9 132311757 132311856 100 - 1.207 1.105 -0.363
ENSG00000107290 E023 138.324549 0.0001323380 0.000000074170622758731418 0.000004449742344682336 9 132326324 132329254 2931 - 2.208 2.078 -0.436
ENSG00000107290 E024 38.802923 0.0003935622 0.215343263349541486073591 0.501118639410530808398 9 132329255 132330499 1245 - 1.630 1.570 -0.205
ENSG00000107290 E025 4.746961 0.0546201285 0.204144649434605557347666 0.486902999275019510161 9 132331052 132331139 88 - 0.844 0.671 -0.701
ENSG00000107290 E026 6.425467 0.0485545880 0.029123175783491824647475 0.160131446906600860558 9 132331277 132331448 172 - 1.005 0.711 -1.138
ENSG00000107290 E027 4.032545 0.0168752682 0.416501575535839274611050 0.696372867969184516923 9 132334608 132334727 120 - 0.755 0.649 -0.441
ENSG00000107290 E028 5.855380 0.0026003856 0.327343956362631027801058 0.619885851706827084584 9 132336296 132336515 220 - 0.890 0.783 -0.419
ENSG00000107290 E029 4.047249 0.1591402643 0.928949371147114622004892 0.979011323179759473945 9 132342690 132342799 110 - 0.690 0.711 0.086
ENSG00000107290 E030 5.779603 0.0084749079 0.756206270400074487270103 0.903922450789355735878 9 132346261 132346471 211 - 0.811 0.844 0.130
ENSG00000107290 E031 4.532219 0.0035107352 0.845404524428888581866204 0.945082472514502391903 9 132349252 132349435 184 - 0.755 0.730 -0.100
ENSG00000107290 E032 2.450271 0.0061220880 0.792186908228371677864743 0.920596597970071761630 9 132353649 132353755 107 - 0.557 0.519 -0.178
ENSG00000107290 E033 1.107063 0.0109079483 0.878010622666486328924407 0.958521520707284246932 9 132354917 132354986 70 - 0.310 0.333 0.144

Help

Please Click HERE to learn more details about the results from DEXseq.