ENSG00000107643

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374176 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding protein_coding 5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.1293332 0.3879996 0.0000000 0.3879996 0.0000000 -5.3146951 0.02427500 0.072825 0.000000 -0.072825 0.85458534 0.01863051 FALSE TRUE
ENST00000395611 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding protein_coding 5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.2967789 0.0000000 0.1089640 0.0000000 0.1089640 3.5724530 0.06750833 0.000000 0.012875 0.012875 0.80371536 0.01863051 FALSE TRUE
ENST00000429041 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding nonsense_mediated_decay 5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.4913461 0.9241848 0.0000000 0.5376232 0.0000000 -6.5456360 0.07036667 0.126400 0.000000 -0.126400 0.46444120 0.01863051 FALSE FALSE
ENST00000469879 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding protein_coding_CDS_not_defined 5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.5037955 1.0755605 0.4358259 0.3596533 0.4358259 -1.2838878 0.07563333 0.175400 0.051500 -0.123900 0.54429905 0.01863051 FALSE TRUE
ENST00000482840 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding protein_coding_CDS_not_defined 5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.1488247 0.4464742 0.0000000 0.2635787 0.0000000 -5.5124614 0.02552500 0.076575 0.000000 -0.076575 0.54150637 0.01863051 FALSE FALSE
MSTRG.3413.2 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding   5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.4715446 0.2918675 1.1227664 0.2918675 0.5428578 1.9078631 0.07945833 0.054775 0.183600 0.128825 0.52032540 0.01863051 FALSE FALSE
MSTRG.3413.6 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding   5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 0.5020241 0.0000000 1.5060722 0.0000000 0.4867488 7.2441946 0.10571667 0.000000 0.317150 0.317150 0.01863051 0.01863051 FALSE TRUE
MSTRG.3413.9 ENSG00000107643 No_inf pgKDN_inf MAPK8 protein_coding   5.785837 6.213842 6.12902 0.7988075 1.058235 -0.01979701 1.9204924 1.5772689 2.0216576 0.2554510 0.8362678 0.3561107 0.33999167 0.272475 0.305900 0.033425 1.00000000 0.01863051 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000107643 E001 0.0000000       10 48306639 48306654 16 +      
ENSG00000107643 E002 0.1176306 0.0124540233 0.6396049360   10 48306655 48306676 22 + 0.087 0.000 -10.453
ENSG00000107643 E003 0.1176306 0.0124540233 0.6396049360   10 48306677 48306679 3 + 0.087 0.000 -12.755
ENSG00000107643 E004 0.2448930 0.0170952877 0.8913288386   10 48306680 48306689 10 + 0.087 0.103 0.272
ENSG00000107643 E005 1.0729133 0.0111708306 0.0264449191 0.150689938 10 48306690 48306752 63 + 0.444 0.103 -2.728
ENSG00000107643 E006 1.5657257 0.0315428011 0.1061526858 0.341027827 10 48306753 48306821 69 + 0.509 0.257 -1.465
ENSG00000107643 E007 0.0000000       10 48307026 48307147 122 +      
ENSG00000107643 E008 0.6250782 0.1952256259 0.1730071144 0.445966912 10 48308095 48308140 46 + 0.087 0.317 2.271
ENSG00000107643 E009 1.3603287 0.0298381594 0.2392861112 0.528207575 10 48308141 48308215 75 + 0.277 0.460 1.080
ENSG00000107643 E010 0.9708926 0.1576492239 0.7350661705 0.894942523 10 48308216 48308288 73 + 0.325 0.257 -0.464
ENSG00000107643 E011 0.7083097 0.0136370760 0.0163714701 0.111220414 10 48325897 48325965 69 + 0.369 0.000 -14.767
ENSG00000107643 E012 0.0000000       10 48364612 48364656 45 +      
ENSG00000107643 E013 1.3254868 0.0097712489 0.2141773076 0.499392111 10 48401612 48401642 31 + 0.444 0.257 -1.143
ENSG00000107643 E014 0.7171237 0.0139836641 0.1405773408 0.398907118 10 48401643 48401647 5 + 0.325 0.103 -2.050
ENSG00000107643 E015 1.0890269 0.0263909127 0.4619842845 0.732562855 10 48401648 48401660 13 + 0.369 0.257 -0.728
ENSG00000107643 E016 3.0223835 0.0054145013 0.1688007567 0.440183422 10 48401661 48401782 122 + 0.680 0.499 -0.815
ENSG00000107643 E017 4.1284086 0.0039038091 0.3874109556 0.673312666 10 48404852 48404981 130 + 0.754 0.653 -0.419
ENSG00000107643 E018 3.0482156 0.0051985367 0.8736910153 0.956917217 10 48409879 48409937 59 + 0.615 0.598 -0.075
ENSG00000107643 E019 3.7670060 0.0038410491 0.4385127239 0.714715219 10 48410030 48410168 139 + 0.719 0.626 -0.391
ENSG00000107643 E020 0.3732278 0.1831331416 0.5245028809   10 48410169 48410328 160 + 0.087 0.187 1.272
ENSG00000107643 E021 3.3041234 0.0045237316 0.7859565134 0.917527675 10 48420155 48420320 166 + 0.615 0.653 0.165
ENSG00000107643 E022 0.3627758 0.0170301967 0.6986086899   10 48424088 48424159 72 + 0.160 0.103 -0.728
ENSG00000107643 E023 0.2541163 0.0164439081 0.1874510171   10 48424514 48424518 5 + 0.000 0.187 13.079
ENSG00000107643 E024 1.5679654 0.1189224092 0.3680722712 0.656634162 10 48424519 48424568 50 + 0.478 0.317 -0.897
ENSG00000107643 E025 1.5679654 0.1189224092 0.3680722712 0.656634162 10 48424569 48424585 17 + 0.478 0.317 -0.897
ENSG00000107643 E026 0.1176306 0.0124540233 0.6396049360   10 48425179 48425188 10 + 0.087 0.000 -12.755
ENSG00000107643 E027 0.1176306 0.0124540233 0.6396049360   10 48425189 48425219 31 + 0.087 0.000 -12.755
ENSG00000107643 E028 1.2266710 0.0159691790 0.7865640126 0.917859397 10 48425220 48425749 530 + 0.325 0.370 0.272
ENSG00000107643 E029 0.1186381 0.0119129601 0.6400752669   10 48425750 48425853 104 + 0.087 0.000 -12.756
ENSG00000107643 E030 0.0000000       10 48425854 48425887 34 +      
ENSG00000107643 E031 4.4916504 0.0041851977 0.3416063690 0.633099834 10 48425888 48426043 156 + 0.787 0.678 -0.444
ENSG00000107643 E032 2.3160460 0.0072205433 0.7647302183 0.908508575 10 48426044 48426070 27 + 0.538 0.499 -0.187
ENSG00000107643 E033 0.2539903 0.0163703346 0.1875116452   10 48426071 48426379 309 + 0.000 0.187 13.079
ENSG00000107643 E034 5.0097579 0.0030462729 0.9209006826 0.975273928 10 48426380 48426504 125 + 0.771 0.786 0.061
ENSG00000107643 E035 1.8636856 0.1207106982 0.0547567317 0.233066812 10 48426505 48427079 575 + 0.276 0.598 1.733
ENSG00000107643 E036 3.4386213 0.0047250302 0.3957295457 0.680676021 10 48427080 48427143 64 + 0.591 0.702 0.479
ENSG00000107643 E037 0.1272623 0.0124738992 0.4506217071   10 48427144 48427410 267 + 0.000 0.103 12.205
ENSG00000107643 E038 1.1425910 0.0137949113 0.0004256251 0.007692917 10 48429893 48431192 1300 + 0.000 0.534 14.804
ENSG00000107643 E039 3.6953864 0.0041274053 0.2218680993 0.509114792 10 48431193 48431270 78 + 0.591 0.746 0.659
ENSG00000107643 E040 1.3480225 0.2438962191 0.9749928305 0.995411363 10 48434879 48434883 5 + 0.369 0.370 0.008
ENSG00000107643 E041 50.8588688 0.0004088222 0.2067577415 0.490385966 10 48434884 48439360 4477 + 1.693 1.737 0.147

Help

Please Click HERE to learn more details about the results from DEXseq.