ENSG00000108179

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000225174 ENSG00000108179 No_inf pgKDN_inf PPIF protein_coding protein_coding 198.6011 37.02031 243.6576 1.506798 2.620939 2.718136 173.509367 28.938705 221.465633 0.2131206 1.281277 2.9355772 0.85063333 0.785575 0.909075 0.123500 0.0002174311 0.0002174311 FALSE TRUE
ENST00000448165 ENSG00000108179 No_inf pgKDN_inf PPIF protein_coding protein_coding 198.6011 37.02031 243.6576 1.506798 2.620939 2.718136 8.223202 4.766644 6.470969 0.6941505 0.690667 0.4402122 0.06570000 0.127750 0.026600 -0.101150 0.0003272238 0.0002174311 FALSE FALSE
ENST00000492149 ENSG00000108179 No_inf pgKDN_inf PPIF protein_coding protein_coding_CDS_not_defined 198.6011 37.02031 243.6576 1.506798 2.620939 2.718136 13.957569 3.314963 13.295713 0.9710046 2.241796 2.0006357 0.07369167 0.086700 0.054325 -0.032375 0.8190113925 0.0002174311 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108179 E001 21.941110 0.0008366913 0.0021645654 0.02708042 10 79347469 79347499 31 + 1.260 0.944 -1.142
ENSG00000108179 E002 79.246416 0.0010786447 0.0181782412 0.11911375 10 79347500 79347657 158 + 1.779 1.657 -0.416
ENSG00000108179 E003 65.667449 0.0039418514 0.4004332693 0.68382782 10 79347658 79347743 86 + 1.690 1.639 -0.173
ENSG00000108179 E004 46.857638 0.0004423357 0.6603885039 0.85830178 10 79349076 79349106 31 + 1.544 1.515 -0.097
ENSG00000108179 E005 75.442811 0.0002071565 0.3992038905 0.68303606 10 79349665 79349753 89 + 1.748 1.705 -0.144
ENSG00000108179 E006 14.411182 0.0030622337 0.0048054496 0.04817191 10 79349754 79350035 282 + 1.004 1.264 0.934
ENSG00000108179 E007 109.355998 0.0026117317 0.2268213691 0.51503719 10 79351487 79351583 97 + 1.909 1.852 -0.191
ENSG00000108179 E008 2.008357 0.0614632592 0.0667129148 0.26020353 10 79351584 79351714 131 + 0.431 0.001 -10.011
ENSG00000108179 E009 98.064604 0.0019984432 0.4917788765 0.75404696 10 79352317 79352392 76 + 1.859 1.826 -0.112
ENSG00000108179 E010 5.683108 0.0024384465 0.0007171199 0.01156080 10 79353645 79353706 62 + 0.613 1.025 1.630
ENSG00000108179 E011 1012.063720 0.0000387997 0.0037895400 0.04092612 10 79353707 79355334 1628 + 2.859 2.880 0.069

Help

Please Click HERE to learn more details about the results from DEXseq.