ENSG00000108306

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264658 ENSG00000108306 No_inf pgKDN_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 4.546531 0.3242661 0.3536704 -0.4522851 3.3721270 5.5283695 2.4776710 0.1077909 0.1676880 -1.154666 0.68744167 0.894000 0.549625 -0.344375 0.04761305 0.04461441 FALSE TRUE
ENST00000394294 ENSG00000108306 No_inf pgKDN_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 4.546531 0.3242661 0.3536704 -0.4522851 0.8419897 0.0000000 1.2845870 0.0000000 0.6054758 7.016348 0.20324167 0.000000 0.257075 0.257075 0.04461441 0.04461441 FALSE TRUE
ENST00000581781 ENSG00000108306 No_inf pgKDN_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 4.546531 0.3242661 0.3536704 -0.4522851 0.1584559 0.4753678 0.0000000 0.2769694 0.0000000 -5.601006 0.02395833 0.071875 0.000000 -0.071875 0.58418785 0.04461441 FALSE TRUE
ENST00000583610 ENSG00000108306 No_inf pgKDN_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 4.546531 0.3242661 0.3536704 -0.4522851 0.1484549 0.0000000 0.4453648 0.0000000 0.4453648 5.508951 0.03930000 0.000000 0.117900 0.117900 0.83389354 0.04461441 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108306 E001 142.7675505 0.0001584170 1.351451e-07 7.672542e-06 17 39252663 39259130 6468 - 2.051 2.151 0.334
ENSG00000108306 E002 3.5818802 0.0039952670 5.286379e-01 7.802047e-01 17 39259131 39259296 166 - 0.691 0.606 -0.363
ENSG00000108306 E003 22.4330367 0.0008628078 4.141367e-02 1.976642e-01 17 39259297 39260586 1290 - 1.239 1.373 0.469
ENSG00000108306 E004 25.5769551 0.0057609586 1.324201e-01 3.862390e-01 17 39260587 39261451 865 - 1.458 1.357 -0.348
ENSG00000108306 E005 1.4772992 0.0090545989 5.039830e-01 7.633482e-01 17 39261452 39261459 8 - 0.443 0.339 -0.588
ENSG00000108306 E006 4.3250852 0.0109606278 5.575787e-01 7.994520e-01 17 39261460 39261567 108 - 0.749 0.673 -0.315
ENSG00000108306 E007 0.2543986 0.0161288779 6.312965e-01   17 39263876 39264174 299 - 0.000 0.126 8.895
ENSG00000108306 E008 8.2732982 0.0018683334 2.621964e-01 5.550178e-01 17 39264175 39264387 213 - 1.010 0.899 -0.416
ENSG00000108306 E009 3.8020032 0.0035810538 6.547764e-02 2.576964e-01 17 39265397 39265453 57 - 0.801 0.568 -0.980
ENSG00000108306 E010 3.4307667 0.0280625246 7.464895e-02 2.785661e-01 17 39268827 39268871 45 - 0.776 0.527 -1.074
ENSG00000108306 E011 4.0725800 0.0037860910 3.968357e-01 6.813362e-01 17 39270796 39270856 61 - 0.749 0.641 -0.452
ENSG00000108306 E012 4.9709359 0.0028424713 7.516815e-01 9.021953e-01 17 39274970 39275100 131 - 0.721 0.758 0.149
ENSG00000108306 E013 2.6070799 0.0058424087 9.231337e-01 9.764133e-01 17 39281389 39281463 75 - 0.542 0.527 -0.074
ENSG00000108306 E014 5.6450668 0.0026112549 2.964593e-02 1.618744e-01 17 39282729 39282855 127 - 0.945 0.703 -0.948
ENSG00000108306 E015 4.4000389 0.0034184744 1.181720e-02 8.970430e-02 17 39285478 39285573 96 - 0.889 0.588 -1.234
ENSG00000108306 E016 4.8910848 0.0033941735 8.964087e-03 7.473629e-02 17 39297127 39297195 69 - 0.927 0.624 -1.218
ENSG00000108306 E017 5.1268268 0.0027631734 2.879732e-03 3.348759e-02 17 39298990 39299084 95 - 0.962 0.624 -1.349
ENSG00000108306 E018 2.8316484 0.0630780771 3.132759e-01 6.064074e-01 17 39301001 39301075 75 - 0.658 0.504 -0.695
ENSG00000108306 E019 3.2212752 0.0223214100 8.097610e-01 9.298226e-01 17 39303585 39303639 55 - 0.623 0.588 -0.156
ENSG00000108306 E020 3.3590147 0.0043313146 7.633210e-01 9.077294e-01 17 39343180 39343241 62 - 0.584 0.624 0.174
ENSG00000108306 E021 3.0637330 0.0235854152 1.260236e-01 3.763959e-01 17 39401361 39401656 296 - 0.721 0.504 -0.958
ENSG00000108306 E022 0.0000000       17 39401666 39401706 41 -      
ENSG00000108306 E023 0.7429938 0.0232360107 9.587746e-01 9.902062e-01 17 39402173 39402523 351 - 0.233 0.224 -0.074

Help

Please Click HERE to learn more details about the results from DEXseq.