ENSG00000108344

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264639 ENSG00000108344 No_inf pgKDN_inf PSMD3 protein_coding protein_coding 64.27642 55.05277 67.0098 2.341423 1.054751 0.28351 56.85465 44.905125 63.030389 0.5110276 0.5628887 0.4890751 0.881875 0.819425 0.94100 0.121575 0.003861919 0.003861919 FALSE TRUE
ENST00000580980 ENSG00000108344 No_inf pgKDN_inf PSMD3 protein_coding retained_intron 64.27642 55.05277 67.0098 2.341423 1.054751 0.28351 6.04287 7.990862 3.094169 2.2681565 0.5613629 -1.3659483 0.095400 0.140975 0.04585 -0.095125 0.204957057 0.003861919 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108344 E001 4.527942 0.0031592134 7.972941e-01 9.234862e-01 17 39980807 39980835 29 + 0.725 0.760 0.142
ENSG00000108344 E002 52.390674 0.0003224922 3.754553e-03 4.063778e-02 17 39980836 39981090 255 + 1.778 1.664 -0.385
ENSG00000108344 E003 41.365973 0.0003535440 3.501536e-02 1.790914e-01 17 39981091 39981190 100 + 1.668 1.577 -0.312
ENSG00000108344 E004 65.191904 0.0002515234 5.435704e-03 5.257698e-02 17 39984294 39984458 165 + 1.864 1.768 -0.325
ENSG00000108344 E005 28.740998 0.0012104047 2.706717e-03 3.192856e-02 17 39984459 39984484 26 + 1.544 1.380 -0.566
ENSG00000108344 E006 29.792737 0.0005324751 7.225544e-02 2.726795e-01 17 39986575 39986608 34 + 1.530 1.438 -0.316
ENSG00000108344 E007 40.635137 0.0003541001 4.145593e-02 1.977784e-01 17 39986609 39986683 75 + 1.660 1.570 -0.304
ENSG00000108344 E008 25.718848 0.0005379323 3.224290e-01 6.153827e-01 17 39986684 39986712 29 + 1.450 1.399 -0.179
ENSG00000108344 E009 62.808726 0.0059808518 3.205471e-01 6.134550e-01 17 39988683 39988819 137 + 1.778 1.831 0.181
ENSG00000108344 E010 48.169868 0.0003525866 7.971889e-02 2.897667e-01 17 39989739 39989793 55 + 1.651 1.731 0.271
ENSG00000108344 E011 72.176530 0.0017031870 4.108384e-01 6.926156e-01 17 39989794 39989929 136 + 1.846 1.882 0.122
ENSG00000108344 E012 4.847516 0.0089382829 5.886885e-03 5.571210e-02 17 39989930 39990093 164 + 0.571 0.910 1.390
ENSG00000108344 E013 66.651443 0.0002851894 6.006643e-01 8.251714e-01 17 39990094 39990197 104 + 1.836 1.823 -0.045
ENSG00000108344 E014 9.414393 0.0017645199 2.466409e-11 2.671151e-09 17 39992998 39994953 1956 + 0.571 1.247 2.612
ENSG00000108344 E015 67.772722 0.0002474118 8.494852e-01 9.464579e-01 17 39994954 39995068 115 + 1.838 1.836 -0.004
ENSG00000108344 E016 74.196598 0.0113788644 3.213990e-01 6.144529e-01 17 39995176 39995295 120 + 1.846 1.906 0.201
ENSG00000108344 E017 73.555791 0.0041688977 6.025970e-02 2.463626e-01 17 39995424 39995527 104 + 1.829 1.914 0.287
ENSG00000108344 E018 7.663329 0.0021115890 1.045673e-02 8.269401e-02 17 39995528 39996120 593 + 0.794 1.053 0.982
ENSG00000108344 E019 75.958539 0.0002263488 3.588046e-01 6.482570e-01 17 39996183 39996338 156 + 1.868 1.904 0.122
ENSG00000108344 E020 1.242127 0.0443417139 1.555335e-01 4.214502e-01 17 39996701 39996793 93 + 0.225 0.455 1.442
ENSG00000108344 E021 38.748865 0.0003870208 7.735200e-01 9.128890e-01 17 39997330 39997380 51 + 1.590 1.609 0.065
ENSG00000108344 E022 45.654427 0.0003324492 7.549621e-01 9.035894e-01 17 39997504 39997793 290 + 1.672 1.664 -0.027
ENSG00000108344 E023 13.688683 0.0016267455 8.668519e-01 9.541243e-01 17 39997794 39997959 166 + 1.158 1.176 0.065

Help

Please Click HERE to learn more details about the results from DEXseq.