ENSG00000108424

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290158 ENSG00000108424 No_inf pgKDN_inf KPNB1 protein_coding protein_coding 151.499 104.2587 179.4858 2.762166 3.272957 0.7836435 12.593648 9.333565 14.86606 0.3407942 0.8035986 0.6709474 0.08410000 0.089900 0.082725 -0.007175 9.273124e-01 4.785339e-20 FALSE TRUE
ENST00000540627 ENSG00000108424 No_inf pgKDN_inf KPNB1 protein_coding protein_coding 151.499 104.2587 179.4858 2.762166 3.272957 0.7836435 57.465860 26.369251 75.54062 1.3907739 0.8493042 1.5180400 0.36284167 0.254400 0.421275 0.166875 1.040832e-03 4.785339e-20 FALSE TRUE
ENST00000577918 ENSG00000108424 No_inf pgKDN_inf KPNB1 protein_coding protein_coding_CDS_not_defined 151.499 104.2587 179.4858 2.762166 3.272957 0.7836435 8.720229 1.687691 11.24889 1.6876908 4.1191678 2.7294189 0.05196667 0.015600 0.063025 0.047425 2.927569e-01 4.785339e-20 FALSE TRUE
ENST00000582097 ENSG00000108424 No_inf pgKDN_inf KPNB1 protein_coding protein_coding 151.499 104.2587 179.4858 2.762166 3.272957 0.7836435 6.254327 14.238589 0.00000 2.2890037 0.0000000 -10.4766033 0.05395833 0.135325 0.000000 -0.135325 4.785339e-20 4.785339e-20 FALSE TRUE
ENST00000677341 ENSG00000108424 No_inf pgKDN_inf KPNB1 protein_coding retained_intron 151.499 104.2587 179.4858 2.762166 3.272957 0.7836435 59.308160 44.331673 68.99083 1.0858795 0.9421026 0.6379505 0.39623333 0.425700 0.384600 -0.041100 7.083380e-01 4.785339e-20 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108424 E001 0.0000000       17 47649476 47649494 19 +      
ENSG00000108424 E002 1.2141791 1.060980e-02 9.635830e-01 9.923262e-01 17 47649495 47649877 383 + 0.338 0.346 0.048
ENSG00000108424 E003 5.9059692 2.530053e-03 1.220967e-01 3.695715e-01 17 47649919 47649985 67 + 0.896 0.722 -0.689
ENSG00000108424 E004 18.5829334 7.456951e-04 1.604279e-02 1.098314e-01 17 47649986 47650151 166 + 1.347 1.177 -0.598
ENSG00000108424 E005 7.1909703 6.259620e-03 6.390061e-01 8.465030e-01 17 47650152 47650177 26 + 0.885 0.936 0.190
ENSG00000108424 E006 25.2940894 1.006234e-03 9.043016e-02 3.122845e-01 17 47650178 47650284 107 + 1.452 1.349 -0.356
ENSG00000108424 E007 0.2543986 1.601012e-02 1.257085e-01   17 47650358 47650385 28 + 0.000 0.207 12.425
ENSG00000108424 E008 27.9466751 8.961595e-04 6.685197e-02 2.605342e-01 17 47650386 47650444 59 + 1.495 1.389 -0.367
ENSG00000108424 E009 1.0693213 1.963700e-02 6.475967e-02 2.565556e-01 17 47651196 47651376 181 + 0.410 0.116 -2.367
ENSG00000108424 E010 66.5758066 2.100010e-04 1.176693e-06 5.373729e-05 17 47652694 47652876 183 + 1.890 1.702 -0.634
ENSG00000108424 E011 38.8445277 3.881291e-04 2.830666e-04 5.533495e-03 17 47656860 47656924 65 + 1.659 1.477 -0.623
ENSG00000108424 E012 72.5909617 2.005631e-04 4.559288e-03 4.642262e-02 17 47656925 47657060 136 + 1.899 1.796 -0.345
ENSG00000108424 E013 69.4841965 2.133316e-04 1.132382e-02 8.729831e-02 17 47658508 47658660 153 + 1.877 1.784 -0.314
ENSG00000108424 E014 1.6051909 8.216625e-03 1.099769e-01 3.480759e-01 17 47660882 47661118 237 + 0.297 0.536 1.311
ENSG00000108424 E015 36.7212615 1.450990e-03 5.298632e-03 5.171907e-02 17 47661119 47661178 60 + 1.624 1.477 -0.504
ENSG00000108424 E016 0.2530140 2.454385e-01 1.666495e-01   17 47662169 47662238 70 + 0.000 0.207 11.304
ENSG00000108424 E017 61.5219623 4.263765e-04 5.811670e-04 9.822833e-03 17 47663089 47663178 90 + 1.840 1.702 -0.466
ENSG00000108424 E018 69.4060054 2.447516e-04 4.902123e-04 8.598085e-03 17 47664159 47664269 111 + 1.889 1.759 -0.439
ENSG00000108424 E019 77.1487122 7.788048e-04 2.204652e-02 1.348596e-01 17 47665057 47665158 102 + 1.918 1.835 -0.279
ENSG00000108424 E020 103.2362302 2.747433e-04 5.384424e-01 7.871254e-01 17 47668186 47668364 179 + 2.018 2.000 -0.059
ENSG00000108424 E021 46.8129321 3.311439e-04 3.724061e-01 6.603114e-01 17 47668365 47668410 46 + 1.688 1.649 -0.132
ENSG00000108424 E022 0.7257453 1.331767e-02 7.656503e-01 9.089251e-01 17 47668411 47668801 391 + 0.252 0.207 -0.367
ENSG00000108424 E023 0.4808523 1.570450e-02 5.722633e-01   17 47669573 47669677 105 + 0.201 0.116 -0.952
ENSG00000108424 E024 102.0948305 1.586322e-04 8.281211e-03 7.077148e-02 17 47669678 47669869 192 + 2.037 1.957 -0.268
ENSG00000108424 E025 0.1176306 1.173096e-02 8.510145e-01   17 47670324 47670343 20 + 0.078 0.000 -11.606
ENSG00000108424 E026 0.0000000       17 47670377 47670457 81 +      
ENSG00000108424 E027 71.8152165 2.016047e-04 8.724360e-01 9.564008e-01 17 47670702 47670832 131 + 1.852 1.859 0.024
ENSG00000108424 E028 0.0000000       17 47671710 47671862 153 +      
ENSG00000108424 E029 52.3652362 3.040893e-04 9.790078e-01 9.973490e-01 17 47673018 47673088 71 + 1.720 1.720 0.001
ENSG00000108424 E030 69.7579086 4.081727e-04 3.175282e-01 6.103108e-01 17 47673089 47673165 77 + 1.857 1.821 -0.121
ENSG00000108424 E031 73.4494451 2.084308e-04 6.297210e-01 8.411826e-01 17 47673490 47673561 72 + 1.857 1.876 0.062
ENSG00000108424 E032 0.2545247 2.664684e-01 1.702297e-01   17 47673562 47673839 278 + 0.000 0.207 11.273
ENSG00000108424 E033 116.1845515 3.029622e-04 3.277641e-01 6.203061e-01 17 47674638 47674782 145 + 2.049 2.079 0.099
ENSG00000108424 E034 1.7507093 7.831341e-03 3.041435e-03 3.487631e-02 17 47675714 47676076 363 + 0.201 0.639 2.508
ENSG00000108424 E035 2.0934365 1.120170e-01 1.990243e-01 4.805412e-01 17 47676077 47676408 332 + 0.376 0.607 1.147
ENSG00000108424 E036 97.5027652 1.565060e-03 6.023142e-01 8.264065e-01 17 47676409 47676491 83 + 1.978 1.998 0.065
ENSG00000108424 E037 131.2977606 1.358463e-04 6.213755e-01 8.366812e-01 17 47677020 47677127 108 + 2.108 2.123 0.048
ENSG00000108424 E038 164.7002234 1.392195e-04 8.575800e-02 3.031772e-01 17 47678046 47678189 144 + 2.194 2.236 0.140
ENSG00000108424 E039 150.9432508 7.727376e-03 8.466704e-01 9.456191e-01 17 47678308 47678413 106 + 2.170 2.181 0.035
ENSG00000108424 E040 16.9818249 1.924148e-03 3.497545e-05 9.850474e-04 17 47678414 47680019 1606 + 1.100 1.399 1.055
ENSG00000108424 E041 165.9204219 5.232524e-04 3.043245e-01 5.977682e-01 17 47680020 47680134 115 + 2.204 2.231 0.090
ENSG00000108424 E042 197.6562318 1.164229e-04 1.010157e-03 1.511705e-02 17 47680508 47680602 95 + 2.260 2.332 0.240
ENSG00000108424 E043 108.2386870 1.526151e-04 1.010664e-01 3.319978e-01 17 47680603 47680669 67 + 2.010 2.060 0.165
ENSG00000108424 E044 59.5061158 2.064593e-03 7.044160e-01 8.798644e-01 17 47682404 47682790 387 + 1.781 1.766 -0.050
ENSG00000108424 E045 497.1911367 6.536658e-05 2.731606e-06 1.109386e-04 17 47682791 47684312 1522 + 2.664 2.725 0.205
ENSG00000108424 E046 38.5248246 5.890938e-03 1.564420e-04 3.411963e-03 17 47684313 47685505 1193 + 1.487 1.705 0.743

Help

Please Click HERE to learn more details about the results from DEXseq.