ENSG00000108578

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261714 ENSG00000108578 No_inf pgKDN_inf BLMH protein_coding protein_coding 22.49398 32.08491 18.54151 3.624334 1.650587 -0.7908075 14.4997767 14.9691727 15.410583 1.6742045 0.6846847 0.04189933 0.71615000 0.498450 0.843200 0.344750 4.906564e-02 5.02193e-08 FALSE TRUE
ENST00000578090 ENSG00000108578 No_inf pgKDN_inf BLMH protein_coding nonsense_mediated_decay 22.49398 32.08491 18.54151 3.624334 1.650587 -0.7908075 1.1820031 2.6313808 0.000000 1.5620644 0.0000000 -8.04514847 0.03915833 0.073375 0.000000 -0.073375 5.586440e-01 5.02193e-08 FALSE TRUE
ENST00000579957 ENSG00000108578 No_inf pgKDN_inf BLMH protein_coding retained_intron 22.49398 32.08491 18.54151 3.624334 1.650587 -0.7908075 0.7769624 2.3308872 0.000000 2.3308872 0.0000000 -7.87091161 0.01847500 0.055425 0.000000 -0.055425 9.103500e-01 5.02193e-08   FALSE
ENST00000582669 ENSG00000108578 No_inf pgKDN_inf BLMH protein_coding protein_coding_CDS_not_defined 22.49398 32.08491 18.54151 3.624334 1.650587 -0.7908075 1.5417185 0.9486662 2.858486 0.5508396 1.2209857 1.58118876 0.07319167 0.035500 0.141425 0.105925 4.172843e-01 5.02193e-08   FALSE
MSTRG.12371.2 ENSG00000108578 No_inf pgKDN_inf BLMH protein_coding   22.49398 32.08491 18.54151 3.624334 1.650587 -0.7908075 3.2658515 8.6812894 0.000000 2.2737048 0.0000000 -9.76342642 0.10402500 0.258250 0.000000 -0.258250 5.021930e-08 5.02193e-08   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108578 E001 0.0000000       17 30248203 30248204 2 -      
ENSG00000108578 E002 58.9153167 0.0002620925 0.01098398 0.08554654 17 30248205 30248821 617 - 1.706 1.801 0.323
ENSG00000108578 E003 49.2275404 0.0003061341 0.27193704 0.56573393 17 30248822 30249168 347 - 1.716 1.673 -0.145
ENSG00000108578 E004 0.3806233 0.0159416764 0.20155693   17 30249169 30250283 1115 - 0.000 0.206 12.383
ENSG00000108578 E005 0.3802150 0.0324703020 0.20459643   17 30263970 30264017 48 - 0.000 0.206 12.317
ENSG00000108578 E006 0.0000000       17 30266879 30266884 6 -      
ENSG00000108578 E007 19.6305248 0.0017890809 0.58183478 0.81379314 17 30266885 30266954 70 - 1.280 1.318 0.132
ENSG00000108578 E008 0.0000000       17 30271269 30271270 2 -      
ENSG00000108578 E009 22.0943794 0.0006501811 0.70054039 0.87797893 17 30271271 30271388 118 - 1.337 1.362 0.087
ENSG00000108578 E010 0.3713386 0.2224766290 0.89571545   17 30271389 30271493 105 - 0.113 0.147 0.448
ENSG00000108578 E011 1.1149955 0.0115418403 0.66198194 0.85899167 17 30272258 30272560 303 - 0.276 0.345 0.448
ENSG00000108578 E012 15.3203762 0.0009360106 0.55291597 0.79626632 17 30272561 30272628 68 - 1.174 1.219 0.161
ENSG00000108578 E013 22.1524382 0.0006578658 0.42698020 0.70555930 17 30272741 30272889 149 - 1.382 1.335 -0.165
ENSG00000108578 E014 5.6787816 0.0028461958 0.85197082 0.94767884 17 30272890 30272899 10 - 0.802 0.824 0.086
ENSG00000108578 E015 0.8707287 0.0875556172 0.54907461 0.79380769 17 30272900 30273130 231 - 0.202 0.303 0.770
ENSG00000108578 E016 0.7255854 0.1404701857 0.25134168 0.54257807 17 30273278 30273479 202 - 0.339 0.147 -1.551
ENSG00000108578 E017 0.6339197 0.0530438581 0.06080536 0.24749154 17 30273765 30274037 273 - 0.000 0.303 12.925
ENSG00000108578 E018 0.0000000       17 30274038 30274041 4 -      
ENSG00000108578 E019 18.4567683 0.0042597355 0.40157807 0.68468724 17 30274042 30274197 156 - 1.313 1.255 -0.204
ENSG00000108578 E020 15.5050030 0.0011260350 0.46613151 0.73491298 17 30285388 30285480 93 - 1.238 1.186 -0.183
ENSG00000108578 E021 0.0000000       17 30285481 30285539 59 -      
ENSG00000108578 E022 9.0409687 0.0015987397 0.27267891 0.56639101 17 30286814 30286851 38 - 0.925 1.030 0.389
ENSG00000108578 E023 7.3962131 0.0050146047 0.85546615 0.94916203 17 30286852 30286902 51 - 0.925 0.907 -0.066
ENSG00000108578 E024 6.7514997 0.0040747455 0.31687971 0.60970533 17 30287806 30287823 18 - 0.940 0.837 -0.394
ENSG00000108578 E025 13.2613649 0.0123113359 0.26939329 0.56298271 17 30287824 30287947 124 - 1.199 1.105 -0.337
ENSG00000108578 E026 6.2524814 0.0026639813 0.22027168 0.50715614 17 30289373 30289413 41 - 0.925 0.796 -0.495
ENSG00000108578 E027 7.9792384 0.0445522032 0.32712804 0.61962927 17 30289414 30289482 69 - 1.008 0.896 -0.418
ENSG00000108578 E028 0.0000000       17 30290990 30291179 190 -      
ENSG00000108578 E029 0.1265070 0.0124176437 0.79821182   17 30291180 30291310 131 - 0.000 0.080 10.878
ENSG00000108578 E030 14.2840250 0.0185350998 0.74399893 0.89873493 17 30291311 30291491 181 - 1.191 1.163 -0.100
ENSG00000108578 E031 5.9046204 0.0101999674 0.66039998 0.85830178 17 30291492 30291508 17 - 0.859 0.810 -0.189
ENSG00000108578 E032 0.1268540 0.0123627852 0.79830130   17 30291589 30291806 218 - 0.000 0.080 10.879
ENSG00000108578 E033 8.7869555 0.0027657779 0.36698348 0.65569757 17 30291807 30291913 107 - 0.925 1.013 0.328
ENSG00000108578 E034 4.1916656 0.0049750451 0.93341767 0.98080869 17 30291914 30292056 143 - 0.712 0.703 -0.037

Help

Please Click HERE to learn more details about the results from DEXseq.