ENSG00000108582

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000225719 ENSG00000108582 No_inf pgKDN_inf CPD protein_coding protein_coding 39.27391 31.50724 38.5466 0.6589418 1.099985 0.2908369 5.669715 2.368082 5.168578 0.2962174 0.8339684 1.12275759 0.1367167 0.075075 0.136200 0.061125 6.030465e-01 1.03744e-09 FALSE TRUE
ENST00000579502 ENSG00000108582 No_inf pgKDN_inf CPD protein_coding nonsense_mediated_decay 39.27391 31.50724 38.5466 0.6589418 1.099985 0.2908369 15.780041 13.936775 14.778782 0.7809137 1.4504142 0.08457167 0.4043000 0.441600 0.382925 -0.058675 8.196674e-01 1.03744e-09   FALSE
ENST00000584221 ENSG00000108582 No_inf pgKDN_inf CPD protein_coding protein_coding 39.27391 31.50724 38.5466 0.6589418 1.099985 0.2908369 1.603723 4.811169 0.000000 0.3370057 0.0000000 -8.91323918 0.0508250 0.152475 0.000000 -0.152475 1.037440e-09 1.03744e-09 FALSE FALSE
MSTRG.12373.5 ENSG00000108582 No_inf pgKDN_inf CPD protein_coding   39.27391 31.50724 38.5466 0.6589418 1.099985 0.2908369 15.679737 10.096360 17.432688 0.2767562 0.9820036 0.78735895 0.3940833 0.321400 0.451400 0.130000 2.853978e-01 1.03744e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108582 E001 11.3571300 1.213952e-03 3.802041e-02 1.880760e-01 17 30378927 30379615 689 + 1.161 0.979 -0.659
ENSG00000108582 E002 2.5262391 5.764074e-02 2.602153e-01 5.528858e-01 17 30379616 30379726 111 + 0.619 0.433 -0.887
ENSG00000108582 E003 0.0000000       17 30380236 30380642 407 +      
ENSG00000108582 E004 0.1272623 1.235019e-02 3.938923e-01   17 30384163 30384189 27 + 0.000 0.109 10.262
ENSG00000108582 E005 11.2964392 1.914524e-02 6.712728e-01 8.636257e-01 17 30384989 30385236 248 + 1.107 1.062 -0.163
ENSG00000108582 E006 0.0000000       17 30385237 30385292 56 +      
ENSG00000108582 E007 11.3215804 1.471348e-03 9.259861e-01 9.777382e-01 17 30420841 30420983 143 + 1.092 1.083 -0.035
ENSG00000108582 E008 12.4621973 1.100116e-03 5.209176e-02 2.266288e-01 17 30421664 30421833 170 + 1.191 1.028 -0.587
ENSG00000108582 E009 22.2410203 6.455385e-04 4.079221e-03 4.301245e-02 17 30422674 30423023 350 + 1.437 1.250 -0.649
ENSG00000108582 E010 19.7092369 6.967449e-04 1.553385e-02 1.077265e-01 17 30423506 30423697 192 + 1.379 1.214 -0.579
ENSG00000108582 E011 16.7086907 2.887668e-03 1.107524e-01 3.492966e-01 17 30427391 30427558 168 + 1.295 1.174 -0.427
ENSG00000108582 E012 12.0822181 2.775953e-02 5.964103e-02 2.448845e-01 17 30431772 30431881 110 + 1.191 0.992 -0.720
ENSG00000108582 E013 6.6345574 5.636409e-03 4.806989e-02 2.157086e-01 17 30438975 30438984 10 + 0.964 0.744 -0.851
ENSG00000108582 E014 11.0051185 1.493797e-03 6.759798e-02 2.623276e-01 17 30438985 30439077 93 + 1.141 0.979 -0.590
ENSG00000108582 E015 16.9352123 1.573412e-03 3.518924e-02 1.795550e-01 17 30442308 30442450 143 + 1.314 1.158 -0.550
ENSG00000108582 E016 18.7054509 2.364635e-02 3.229514e-02 1.700982e-01 17 30443802 30443971 170 + 1.371 1.166 -0.722
ENSG00000108582 E017 0.0000000       17 30443972 30444144 173 +      
ENSG00000108582 E018 32.1656294 4.493861e-04 1.234222e-06 5.596225e-05 17 30445691 30446020 330 + 1.617 1.349 -0.922
ENSG00000108582 E019 0.0000000       17 30447562 30447564 3 +      
ENSG00000108582 E020 15.3853113 3.577026e-03 1.238837e-01 3.727914e-01 17 30449553 30449672 120 + 1.262 1.140 -0.431
ENSG00000108582 E021 9.5968121 1.859325e-02 6.191157e-01 8.353359e-01 17 30449673 30449748 76 + 1.046 0.992 -0.196
ENSG00000108582 E022 0.2363338 1.572285e-02 3.658871e-01   17 30450236 30450294 59 + 0.153 0.000 -11.714
ENSG00000108582 E023 8.6380920 2.056495e-03 9.781231e-01 9.969214e-01 17 30451711 30451756 46 + 0.984 0.979 -0.017
ENSG00000108582 E024 12.9435499 1.028766e-03 6.504065e-02 2.568763e-01 17 30451757 30451809 53 + 1.203 1.051 -0.546
ENSG00000108582 E025 10.5197146 1.306817e-03 5.202289e-02 2.264936e-01 17 30451810 30451846 37 + 1.128 0.953 -0.641
ENSG00000108582 E026 0.0000000       17 30454021 30455338 1318 +      
ENSG00000108582 E027 20.2052352 2.946565e-03 1.636839e-02 1.112204e-01 17 30455339 30455470 132 + 1.391 1.221 -0.592
ENSG00000108582 E028 0.0000000       17 30455471 30456255 785 +      
ENSG00000108582 E029 14.8152044 1.202938e-02 3.596083e-01 6.491002e-01 17 30456256 30456324 69 + 1.231 1.149 -0.290
ENSG00000108582 E030 9.7071147 1.586418e-02 3.183348e-01 6.110859e-01 17 30456325 30456351 27 + 1.070 0.966 -0.381
ENSG00000108582 E031 16.1430959 8.322191e-03 2.391289e-01 5.280966e-01 17 30456462 30456526 65 + 1.272 1.174 -0.344
ENSG00000108582 E032 0.1187032 1.187042e-02 7.301966e-01   17 30456527 30456863 337 + 0.083 0.000 -10.781
ENSG00000108582 E033 28.0463904 4.863444e-03 1.891620e-01 4.677491e-01 17 30461180 30461311 132 + 1.496 1.411 -0.293
ENSG00000108582 E034 37.1753788 4.010565e-04 2.089857e-01 4.931305e-01 17 30461877 30462062 186 + 1.606 1.542 -0.218
ENSG00000108582 E035 10.8955717 1.343141e-03 1.255433e-01 3.755645e-01 17 30462370 30462395 26 + 1.128 0.992 -0.494
ENSG00000108582 E036 16.5412307 8.547345e-04 6.429010e-01 8.486527e-01 17 30462396 30462469 74 + 1.257 1.221 -0.124
ENSG00000108582 E037 315.4112270 1.038371e-04 4.904532e-03 4.888579e-02 17 30464588 30466246 1659 + 2.479 2.519 0.133
ENSG00000108582 E038 401.3854592 8.545682e-05 1.267487e-17 2.734426e-15 17 30466247 30469989 3743 + 2.553 2.657 0.347

Help

Please Click HERE to learn more details about the results from DEXseq.