ENSG00000108639

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000225777 ENSG00000108639 No_inf pgKDN_inf SYNGR2 protein_coding protein_coding 101.1448 64.44198 113.6188 0.5154713 1.105313 0.8180318 96.16139 58.81458 110.238 1.576195 1.406659 0.9062621 0.94515 0.912625 0.970175 0.05755 0.009804864 0.009804864 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108639 E001 4.8268592 0.0138673685 4.263329e-01 0.7049626577 17 78168581 78168593 13 + 0.799 0.697 -0.412
ENSG00000108639 E002 8.3566553 0.0019472630 6.364757e-01 0.8448856354 17 78168594 78168601 8 + 0.983 0.937 -0.174
ENSG00000108639 E003 9.4618280 0.0023446226 9.204770e-01 0.9752145588 17 78168602 78168603 2 + 1.017 1.007 -0.036
ENSG00000108639 E004 11.7490813 0.0012000166 5.529102e-01 0.7962663209 17 78168604 78168609 6 + 1.119 1.068 -0.183
ENSG00000108639 E005 13.0830970 0.0010608218 5.346921e-01 0.7846112049 17 78168610 78168610 1 + 1.162 1.111 -0.181
ENSG00000108639 E006 16.5512927 0.0008074430 9.417080e-02 0.3193340437 17 78168611 78168617 7 + 1.284 1.160 -0.438
ENSG00000108639 E007 57.2437586 0.0002715042 1.718429e-02 0.1146767705 17 78168618 78168715 98 + 1.795 1.698 -0.326
ENSG00000108639 E008 0.1170040 0.0116744688 8.632656e-01   17 78169158 78169229 72 + 0.078 0.000 -7.446
ENSG00000108639 E009 6.5780444 0.0044572129 3.427275e-05 0.0009682308 17 78169684 78170611 928 + 0.637 1.079 1.724
ENSG00000108639 E010 2.6116798 0.0149073275 3.744046e-03 0.0405403331 17 78170612 78170816 205 + 0.338 0.747 1.964
ENSG00000108639 E011 141.3041623 0.0011871766 1.697157e-02 0.1137497806 17 78170817 78171054 238 + 2.171 2.106 -0.219
ENSG00000108639 E012 2.5823749 0.0566143280 2.759614e-01 0.5693405300 17 78171055 78171509 455 + 0.471 0.640 0.779
ENSG00000108639 E013 100.0347509 0.0004574776 5.711259e-01 0.8073361435 17 78171510 78171649 140 + 1.990 2.007 0.055
ENSG00000108639 E014 1.4680479 0.0723873963 5.015347e-01 0.7614934753 17 78171650 78171738 89 + 0.338 0.452 0.642
ENSG00000108639 E015 150.5384634 0.0001384592 1.944678e-01 0.4743584512 17 78171739 78171942 204 + 2.161 2.191 0.100
ENSG00000108639 E016 412.3816707 0.0001480452 1.464758e-01 0.4075540644 17 78171943 78173090 1148 + 2.602 2.619 0.055
ENSG00000108639 E017 0.3611417 0.0165298218 9.069530e-01   17 78173091 78173527 437 + 0.144 0.116 -0.358

Help

Please Click HERE to learn more details about the results from DEXseq.