ENSG00000108654

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000540698 ENSG00000108654 No_inf pgKDN_inf DDX5 protein_coding nonsense_mediated_decay 1070.166 1123.969 919.4191 329.2498 184.4637 -0.2898047 83.29164 38.536343 113.52953 4.1127310 4.937133 1.5585287 0.09117500 0.044525 0.138575 0.094050 0.006586996 0.002775799 FALSE  
ENST00000581130 ENSG00000108654 No_inf pgKDN_inf DDX5 protein_coding miRNA 1070.166 1123.969 919.4191 329.2498 184.4637 -0.2898047 638.32749 735.003696 404.96474 332.1915009 159.879853 -0.8599392 0.50906667 0.510300 0.374725 -0.135575 0.936556385 0.002775799    
ENST00000581230 ENSG00000108654 No_inf pgKDN_inf DDX5 protein_coding retained_intron 1070.166 1123.969 919.4191 329.2498 184.4637 -0.2898047 133.60402 169.228457 105.00337 1.6717696 1.464369 -0.6884844 0.15334167 0.213800 0.131075 -0.082725 0.749466150 0.002775799 TRUE  
ENST00000581693 ENSG00000108654 No_inf pgKDN_inf DDX5 protein_coding nonsense_mediated_decay 1070.166 1123.969 919.4191 329.2498 184.4637 -0.2898047 76.13048 62.854196 106.33583 4.2095772 4.843094 0.7584529 0.09026667 0.080400 0.136125 0.055725 0.475168769 0.002775799 FALSE  
ENST00000581806 ENSG00000108654 No_inf pgKDN_inf DDX5 protein_coding protein_coding 1070.166 1123.969 919.4191 329.2498 184.4637 -0.2898047 32.51423 1.326244 69.75208 0.8276927 5.106869 5.7061878 0.03830833 0.002400 0.087950 0.085550 0.002775799 0.002775799    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108654 E001 0.3634701 1.669258e-02 5.161568e-01   17 64498254 64498256 3 - 0.181 0.091 -1.157
ENSG00000108654 E002 0.3634701 1.669258e-02 5.161568e-01   17 64498257 64498257 1 - 0.181 0.091 -1.157
ENSG00000108654 E003 0.6168311 1.433029e-02 7.487522e-01 9.008478e-01 17 64498258 64498258 1 - 0.181 0.229 0.428
ENSG00000108654 E004 1.8519738 9.838585e-03 5.825213e-01 8.140145e-01 17 64498259 64498282 24 - 0.407 0.489 0.428
ENSG00000108654 E005 94.3890822 4.336020e-04 4.860957e-15 8.270374e-13 17 64498283 64499615 1333 - 1.815 2.078 0.883
ENSG00000108654 E006 28.0035292 4.934647e-04 3.356111e-02 1.742813e-01 17 64499616 64499635 20 - 1.389 1.512 0.423
ENSG00000108654 E007 84.6245693 2.882792e-04 4.954143e-01 7.565871e-01 17 64499636 64499694 59 - 1.917 1.942 0.082
ENSG00000108654 E008 484.2571169 6.760447e-05 9.794903e-02 3.263793e-01 17 64499695 64499913 219 - 2.696 2.674 -0.071
ENSG00000108654 E009 727.3645701 3.453066e-05 2.417813e-01 5.314950e-01 17 64499914 64500133 220 - 2.852 2.867 0.049
ENSG00000108654 E010 343.8695564 1.234015e-03 4.500145e-01 7.234949e-01 17 64500134 64500184 51 - 2.526 2.544 0.060
ENSG00000108654 E011 633.2314153 2.124301e-03 5.899956e-01 8.184578e-01 17 64500185 64500326 142 - 2.793 2.806 0.043
ENSG00000108654 E012 120.0922373 1.553662e-04 5.362368e-17 1.099673e-14 17 64500327 64500548 222 - 1.932 2.176 0.816
ENSG00000108654 E013 702.6237850 1.120645e-04 4.862746e-02 2.172526e-01 17 64500549 64500773 225 - 2.857 2.836 -0.072
ENSG00000108654 E014 151.5738896 1.417707e-04 1.151135e-21 3.609612e-19 17 64500774 64500882 109 - 2.029 2.278 0.831
ENSG00000108654 E015 126.3347802 9.959581e-04 2.595630e-16 5.017660e-14 17 64500883 64500986 104 - 1.946 2.201 0.854
ENSG00000108654 E016 102.9400898 4.561177e-03 1.109516e-09 9.350099e-08 17 64500987 64501056 70 - 1.855 2.114 0.872
ENSG00000108654 E017 97.7099092 1.605234e-04 1.655267e-09 1.354707e-07 17 64501057 64501143 87 - 1.878 2.070 0.645
ENSG00000108654 E018 100.3862434 3.348919e-04 6.544075e-09 4.802016e-07 17 64501144 64501213 70 - 1.894 2.079 0.622
ENSG00000108654 E019 86.2910393 1.893604e-04 7.101396e-08 4.284191e-06 17 64501214 64501260 47 - 1.830 2.013 0.613
ENSG00000108654 E020 215.9515828 1.231640e-03 5.026184e-18 1.153541e-15 17 64501261 64501472 212 - 2.198 2.423 0.752
ENSG00000108654 E021 351.4419909 6.110864e-05 3.827283e-51 6.658731e-48 17 64501473 64501891 419 - 2.388 2.643 0.850
ENSG00000108654 E022 125.9450746 3.905963e-04 5.164596e-18 1.180285e-15 17 64501892 64502009 118 - 1.946 2.199 0.847
ENSG00000108654 E023 262.1266826 7.797272e-05 2.337316e-03 2.867625e-02 17 64502010 64502069 60 - 2.448 2.392 -0.185
ENSG00000108654 E024 9.5180783 1.087092e-02 1.251798e-01 3.750425e-01 17 64502070 64502161 92 - 0.929 1.084 0.570
ENSG00000108654 E025 306.3807568 6.083065e-04 3.506912e-03 3.883017e-02 17 64502162 64502223 62 - 2.516 2.459 -0.188
ENSG00000108654 E026 25.2366719 5.768552e-04 1.890478e-03 2.451575e-02 17 64502224 64502438 215 - 1.304 1.493 0.656
ENSG00000108654 E027 394.9859151 5.367823e-04 1.235976e-04 2.823427e-03 17 64502439 64502549 111 - 2.631 2.564 -0.221
ENSG00000108654 E028 2.5767436 3.075938e-02 9.732298e-01 9.951310e-01 17 64502550 64502584 35 - 0.554 0.550 -0.019
ENSG00000108654 E029 6.3122798 4.913038e-02 1.699869e-01 4.420747e-01 17 64502585 64502729 145 - 0.752 0.937 0.718
ENSG00000108654 E030 6.3415816 1.199836e-01 1.173387e-01 3.618587e-01 17 64502730 64502899 170 - 0.688 0.971 1.107
ENSG00000108654 E031 1.7315127 1.906776e-01 6.365201e-01 8.448856e-01 17 64502900 64502920 21 - 0.360 0.489 0.692
ENSG00000108654 E032 1.3670351 3.835607e-01 5.031204e-01 7.626559e-01 17 64502921 64502925 5 - 0.249 0.456 1.260
ENSG00000108654 E033 191.8589469 2.834972e-04 2.078738e-02 1.299428e-01 17 64502926 64502964 39 - 2.310 2.260 -0.170
ENSG00000108654 E034 337.6198155 6.012237e-05 4.052563e-07 2.044630e-05 17 64502965 64503094 130 - 2.571 2.489 -0.273
ENSG00000108654 E035 124.7450060 1.235334e-04 1.113342e-04 2.598313e-03 17 64503095 64503098 4 - 2.151 2.048 -0.346
ENSG00000108654 E036 2.4853580 5.474499e-03 1.220716e-01 3.695715e-01 17 64503099 64503187 89 - 0.407 0.628 1.066
ENSG00000108654 E037 276.4117503 1.363517e-04 1.950730e-05 6.050067e-04 17 64503188 64503298 111 - 2.482 2.404 -0.259
ENSG00000108654 E038 159.9050279 2.605695e-03 9.729917e-02 3.249169e-01 17 64503299 64503348 50 - 2.232 2.181 -0.170
ENSG00000108654 E039 3.2213987 4.557239e-03 2.008561e-01 4.829249e-01 17 64503349 64503429 81 - 0.522 0.694 0.761
ENSG00000108654 E040 308.0170513 7.811499e-05 1.844861e-04 3.912730e-03 17 64503430 64503567 138 - 2.522 2.458 -0.211
ENSG00000108654 E041 126.9238645 2.592527e-04 2.355091e-03 2.883529e-02 17 64503568 64503571 4 - 2.148 2.066 -0.274
ENSG00000108654 E042 1.2188699 3.879530e-01 4.235745e-01 7.028386e-01 17 64503572 64503802 231 - 0.407 0.285 -0.743
ENSG00000108654 E043 177.6210698 1.403655e-04 1.366568e-03 1.905987e-02 17 64503803 64503838 36 - 2.288 2.216 -0.240
ENSG00000108654 E044 158.1773372 1.094260e-04 2.936976e-03 3.399778e-02 17 64503839 64503855 17 - 2.237 2.167 -0.235
ENSG00000108654 E045 132.5430658 5.867532e-04 2.270832e-02 1.371939e-01 17 64503856 64503868 13 - 2.157 2.095 -0.207
ENSG00000108654 E046 1.3698646 9.029363e-03 1.811807e-01 4.570381e-01 17 64503869 64503982 114 - 0.249 0.456 1.258
ENSG00000108654 E047 124.3529506 1.439535e-04 2.302108e-02 1.384211e-01 17 64503983 64503994 12 - 2.128 2.068 -0.202
ENSG00000108654 E048 158.2383402 1.117453e-04 4.991625e-03 4.955242e-02 17 64503995 64504014 20 - 2.235 2.169 -0.222
ENSG00000108654 E049 187.9871082 2.234742e-04 3.010103e-05 8.677013e-04 17 64504015 64504059 45 - 2.323 2.230 -0.311
ENSG00000108654 E050 220.2226781 8.866087e-05 1.961755e-05 6.077271e-04 17 64504060 64504116 57 - 2.388 2.302 -0.287
ENSG00000108654 E051 0.9899288 1.182117e-02 5.847051e-01 8.153960e-01 17 64504117 64504221 105 - 0.249 0.334 0.580
ENSG00000108654 E052 226.7294917 8.731196e-05 1.707858e-05 5.392951e-04 17 64504222 64504272 51 - 2.400 2.315 -0.285
ENSG00000108654 E053 215.5069517 1.580146e-04 9.079519e-06 3.143099e-04 17 64504273 64504318 46 - 2.381 2.290 -0.306
ENSG00000108654 E054 1.9949387 3.874262e-02 9.022324e-02 3.119895e-01 17 64504319 64504676 358 - 0.308 0.578 1.428
ENSG00000108654 E055 409.7956638 5.934256e-05 8.774556e-11 8.862301e-09 17 64504677 64504842 166 - 2.661 2.566 -0.318
ENSG00000108654 E056 0.7537251 1.332922e-02 1.216507e-01 3.692517e-01 17 64504843 64504880 38 - 0.100 0.334 2.165
ENSG00000108654 E057 1.1161576 1.094045e-02 4.050520e-01 6.877837e-01 17 64504881 64505040 160 - 0.249 0.379 0.843
ENSG00000108654 E058 0.7322620 1.419524e-02 8.916092e-01 9.639750e-01 17 64505041 64505218 178 - 0.249 0.229 -0.157
ENSG00000108654 E059 0.4996084 3.031059e-02 3.802885e-01   17 64505219 64505285 67 - 0.100 0.229 1.428
ENSG00000108654 E060 0.8716689 4.365096e-02 3.306076e-01 6.231343e-01 17 64505286 64505438 153 - 0.181 0.334 1.165
ENSG00000108654 E061 0.9975154 1.209113e-02 2.016695e-01 4.840392e-01 17 64505439 64505745 307 - 0.181 0.379 1.428
ENSG00000108654 E062 0.6185939 1.433708e-02 7.485867e-01 9.007414e-01 17 64505746 64506075 330 - 0.181 0.229 0.428
ENSG00000108654 E063 271.3309432 5.450247e-04 6.931500e-05 1.741237e-03 17 64506076 64506259 184 - 2.475 2.395 -0.267
ENSG00000108654 E064 39.6739052 6.481567e-03 3.737357e-01 6.614511e-01 17 64506260 64506262 3 - 1.635 1.583 -0.175
ENSG00000108654 E065 36.8150999 4.618474e-03 1.684871e-01 4.397839e-01 17 64506263 64506513 251 - 1.616 1.539 -0.262
ENSG00000108654 E066 4.3204078 3.363771e-02 4.466713e-01 7.210430e-01 17 64506514 64506731 218 - 0.664 0.769 0.428
ENSG00000108654 E067 3.9572650 5.872642e-03 2.795126e-01 5.728008e-01 17 64506755 64506926 172 - 0.613 0.751 0.580
ENSG00000108654 E068 0.0000000       17 64506927 64507314 388 -      
ENSG00000108654 E069 0.0000000       17 64507315 64507477 163 -      
ENSG00000108654 E070 0.1271363 1.236166e-02 6.015692e-01   17 64507478 64507712 235 - 0.000 0.091 8.578
ENSG00000108654 E071 0.2459655 1.655553e-02 9.303659e-01   17 64508057 64508199 143 - 0.100 0.091 -0.157

Help

Please Click HERE to learn more details about the results from DEXseq.