ENSG00000108840

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000586339 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding retained_intron 60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 3.735110 8.015789 1.4611057 1.5925079 1.0263468 -2.4477423 0.05260833 0.086800 0.031325 -0.055475 0.41312074 0.01990242    
ENST00000588419 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding retained_intron 60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 7.624146 12.507995 4.9318546 1.3442344 2.9743218 -1.3408790 0.11635000 0.133975 0.102100 -0.031875 0.67894364 0.01990242 FALSE  
ENST00000593013 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding retained_intron 60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 3.733067 8.142051 0.4741943 1.0220494 0.4741943 -4.0735050 0.05240000 0.087100 0.013350 -0.073750 0.04340204 0.01990242 FALSE  
MSTRG.12721.10 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding   60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 10.321204 14.910069 8.8598082 2.6776298 1.0604698 -0.7502794 0.17804167 0.157575 0.212975 0.055400 0.71633755 0.01990242 FALSE  
MSTRG.12721.6 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding   60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 5.900879 8.569292 6.3679450 2.1361780 1.0767502 -0.4277670 0.10396667 0.094525 0.152175 0.057650 0.67020700 0.01990242 FALSE  
MSTRG.12721.8 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding   60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 8.523116 10.465139 8.0368059 0.3421059 2.8197241 -0.3804813 0.15777500 0.112900 0.206775 0.093875 0.78985677 0.01990242 FALSE  
MSTRG.12721.9 ENSG00000108840 No_inf pgKDN_inf HDAC5 protein_coding   60.20546 93.26756 41.90764 3.390219 3.849083 -1.153972 14.507976 22.921653 7.9520187 0.7512871 2.8332207 -1.5261342 0.23770833 0.245975 0.189275 -0.056700 0.82513578 0.01990242 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108840 E001 0.0000000       17 44076746 44076752 7 -      
ENSG00000108840 E002 0.0000000       17 44076753 44076753 1 -      
ENSG00000108840 E003 3.8775968 0.0165086253 2.455652e-01 0.5360959404 17 44076754 44077565 812 - 0.540 0.706 0.730
ENSG00000108840 E004 0.3808443 0.0359178377 3.431109e-01   17 44077566 44078169 604 - 0.000 0.179 11.079
ENSG00000108840 E005 0.7623792 0.0262219855 7.524159e-02 0.2800414092 17 44078170 44078284 115 - 0.000 0.306 12.069
ENSG00000108840 E006 0.8698452 0.0139674610 8.209612e-01 0.9350145039 17 44078285 44078293 9 - 0.231 0.267 0.274
ENSG00000108840 E007 0.9969815 0.0157153545 6.440564e-01 0.8492210173 17 44078294 44078294 1 - 0.231 0.306 0.537
ENSG00000108840 E008 1.6312481 0.0135706627 1.646267e-01 0.4339038822 17 44078295 44078302 8 - 0.231 0.458 1.412
ENSG00000108840 E009 4.9775749 0.0116369821 5.067168e-01 0.7654462624 17 44078303 44078351 49 - 0.688 0.774 0.351
ENSG00000108840 E010 6.7085525 0.0022646049 6.437764e-01 0.8490774342 17 44078352 44078357 6 - 0.822 0.873 0.200
ENSG00000108840 E011 24.3804129 0.0006343094 2.275222e-01 0.5159645376 17 44078358 44078415 58 - 1.316 1.395 0.274
ENSG00000108840 E012 53.4322623 0.0002956246 2.920717e-01 0.5855521149 17 44078500 44078607 108 - 1.670 1.717 0.159
ENSG00000108840 E013 54.1210737 0.0002929736 5.043337e-02 0.2219200102 17 44078608 44078665 58 - 1.646 1.733 0.295
ENSG00000108840 E014 2.1298539 0.0209620539 1.792018e-01 0.4543098505 17 44078666 44078794 129 - 0.313 0.529 1.175
ENSG00000108840 E015 70.7076521 0.0002355108 1.334972e-01 0.3881632378 17 44078795 44078879 85 - 1.782 1.839 0.195
ENSG00000108840 E016 62.3514521 0.0002499420 3.060692e-01 0.5992616756 17 44079144 44079277 134 - 1.739 1.781 0.142
ENSG00000108840 E017 1.5133644 0.0283098076 5.269607e-02 0.2280944983 17 44079278 44079336 59 - 0.131 0.458 2.412
ENSG00000108840 E018 0.0000000       17 44080107 44080225 119 -      
ENSG00000108840 E019 0.0000000       17 44080401 44080498 98 -      
ENSG00000108840 E020 0.0000000       17 44080763 44080882 120 -      
ENSG00000108840 E021 0.0000000       17 44081571 44081596 26 -      
ENSG00000108840 E022 15.7058469 0.0021998451 1.399842e-05 0.0004570162 17 44081597 44082583 987 - 0.886 1.280 1.432
ENSG00000108840 E023 1.2690366 0.0105541524 1.200678e-02 0.0905570829 17 44082584 44082584 1 - 0.000 0.432 12.799
ENSG00000108840 E024 39.4007405 0.0004348485 2.612195e-01 0.5539065903 17 44082585 44082672 88 - 1.533 1.591 0.199
ENSG00000108840 E025 47.4368576 0.0006212997 4.809961e-01 0.7461879110 17 44082765 44082820 56 - 1.629 1.662 0.114
ENSG00000108840 E026 59.8342527 0.0006643663 6.278283e-01 0.8400229038 17 44083545 44083652 108 - 1.736 1.757 0.071
ENSG00000108840 E027 38.6348874 0.0004062695 4.409736e-01 0.7166286794 17 44083805 44083854 50 - 1.537 1.577 0.137
ENSG00000108840 E028 56.9408333 0.0002688957 7.967905e-01 0.9231616637 17 44084555 44084675 121 - 1.722 1.733 0.038
ENSG00000108840 E029 59.5406420 0.0002488768 2.698869e-01 0.5635202825 17 44085022 44085155 134 - 1.779 1.735 -0.150
ENSG00000108840 E030 1.0078067 0.0348798526 2.055416e-01 0.4888729128 17 44085156 44085355 200 - 0.131 0.341 1.760
ENSG00000108840 E031 71.0146659 0.0003040317 4.945232e-03 0.0492202201 17 44086572 44086737 166 - 1.892 1.790 -0.347
ENSG00000108840 E032 0.2539903 0.0160448658 6.183462e-01   17 44086738 44086755 18 - 0.000 0.127 10.505
ENSG00000108840 E033 65.9146590 0.0002213759 4.750882e-02 0.2142783883 17 44087412 44087696 285 - 1.843 1.767 -0.254
ENSG00000108840 E034 24.9222725 0.0042986886 9.473573e-01 0.9860619279 17 44088387 44088447 61 - 1.378 1.383 0.017
ENSG00000108840 E035 46.2873380 0.0003044580 2.631958e-01 0.5561177192 17 44088448 44088598 151 - 1.676 1.625 -0.173
ENSG00000108840 E036 20.4837384 0.0009074142 7.713564e-01 0.9118412170 17 44091270 44091292 23 - 1.286 1.306 0.072
ENSG00000108840 E037 54.2396404 0.0061632716 7.210883e-01 0.8876706011 17 44091293 44091492 200 - 1.695 1.715 0.068
ENSG00000108840 E038 39.4302052 0.0003715894 1.352475e-01 0.3909049056 17 44091700 44091831 132 - 1.519 1.596 0.265
ENSG00000108840 E039 36.8746727 0.0054518315 6.869645e-01 0.8709010548 17 44092172 44092284 113 - 1.528 1.553 0.085
ENSG00000108840 E040 15.9008899 0.0069391626 6.346355e-02 0.2535158865 17 44092381 44092395 15 - 1.293 1.144 -0.528
ENSG00000108840 E041 41.7315513 0.0003685983 4.037869e-01 0.6866087043 17 44092396 44092527 132 - 1.625 1.585 -0.137
ENSG00000108840 E042 28.1236995 0.0171851548 8.567769e-01 0.9497164582 17 44092676 44092763 88 - 1.443 1.427 -0.057
ENSG00000108840 E043 22.0468993 0.0135230272 6.862749e-01 0.8703950916 17 44092764 44092806 43 - 1.351 1.321 -0.108
ENSG00000108840 E044 32.4684701 0.0052422438 6.071617e-02 0.2473929622 17 44093092 44093206 115 - 1.567 1.453 -0.389
ENSG00000108840 E045 28.1471941 0.0302323632 9.341469e-01 0.9810236738 17 44093314 44093455 142 - 1.438 1.429 -0.029
ENSG00000108840 E046 10.2627382 0.0014395426 3.635279e-01 0.6524189683 17 44093456 44093482 27 - 1.076 0.994 -0.301
ENSG00000108840 E047 7.1404632 0.0021194592 9.811553e-02 0.3266923671 17 44093483 44093485 3 - 0.991 0.821 -0.647
ENSG00000108840 E048 0.0000000       17 44093486 44093505 20 -      
ENSG00000108840 E049 16.1076125 0.0008451210 7.604436e-01 0.9063214854 17 44093575 44093663 89 - 1.217 1.194 -0.081
ENSG00000108840 E050 12.5313385 0.0384716448 8.723378e-01 0.9564008276 17 44093664 44093697 34 - 1.089 1.105 0.060
ENSG00000108840 E051 13.8588710 0.0197448789 5.542388e-01 0.7970858404 17 44093698 44093780 83 - 1.178 1.122 -0.200
ENSG00000108840 E052 13.9924635 0.0096098242 5.579054e-01 0.7996844801 17 44093781 44093834 54 - 1.178 1.128 -0.180
ENSG00000108840 E053 0.3815350 0.0303773861 3.426550e-01   17 44103093 44103151 59 - 0.000 0.179 11.081
ENSG00000108840 E054 14.1956624 0.0357259410 2.681473e-01 0.5616371107 17 44110729 44110800 72 - 1.226 1.111 -0.410
ENSG00000108840 E055 4.1980156 0.0033855652 4.925761e-01 0.7547144905 17 44110801 44110803 3 - 0.746 0.660 -0.356
ENSG00000108840 E056 20.9962516 0.0006695571 1.657948e-01 0.4356862660 17 44110804 44111341 538 - 1.371 1.280 -0.320
ENSG00000108840 E057 18.0452080 0.0026776938 2.093305e-01 0.4935749500 17 44117494 44117704 211 - 1.309 1.217 -0.321
ENSG00000108840 E058 1.2426000 0.1041221721 8.936236e-01 0.9647829277 17 44123254 44123503 250 - 0.313 0.341 0.174
ENSG00000108840 E059 12.9717170 0.0013615259 3.293763e-01 0.6217478922 17 44123504 44123702 199 - 1.168 1.088 -0.289

Help

Please Click HERE to learn more details about the results from DEXseq.