ENSG00000108846

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000285238 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding protein_coding 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 2.1465257 0.9136725 3.1400485 0.5813625 1.2133688 1.76992078 0.05870000 0.052125 0.078150 0.026025 0.84336099 0.01534393 FALSE  
ENST00000427699 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding protein_coding 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 10.0859747 3.0560134 12.5685292 1.1949837 0.2307512 2.03652734 0.27755000 0.183900 0.325700 0.141800 0.63084361 0.01534393 FALSE  
ENST00000503337 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding retained_intron 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 3.0514277 2.6444378 2.1571207 0.2348689 0.2452425 -0.29262685 0.10124167 0.152200 0.055300 -0.096900 0.17822526 0.01534393 FALSE  
ENST00000504586 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding retained_intron 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 3.3452096 0.4938182 5.7630843 0.4938182 3.0524697 3.51836724 0.07581667 0.023525 0.129975 0.106450 0.45293740 0.01534393    
ENST00000505699 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding nonsense_mediated_decay 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 1.1061469 1.4805829 0.0000000 0.5336862 0.0000000 -7.21973278 0.04379167 0.084550 0.000000 -0.084550 0.01540934 0.01534393 TRUE  
ENST00000513589 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding protein_coding_CDS_not_defined 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 1.2613248 1.6494270 0.9549342 1.6494270 0.9549342 -0.78218273 0.04057500 0.078600 0.021900 -0.056700 0.93743371 0.01534393 FALSE  
ENST00000515070 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding retained_intron 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 0.6146118 1.3078114 0.0000000 0.4620207 0.0000000 -7.04200016 0.02748333 0.072800 0.000000 -0.072800 0.01534393 0.01534393 FALSE  
ENST00000571855 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding retained_intron 34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 1.7265142 0.9144953 1.6071704 0.2726971 0.1340790 0.80673385 0.05230000 0.052700 0.042225 -0.010475 0.96669797 0.01534393 FALSE  
MSTRG.12931.15 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding   34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 2.1003202 1.3403290 4.1274561 0.4789625 0.8460938 1.61543309 0.06518333 0.076650 0.101800 0.025150 0.83750218 0.01534393 FALSE  
MSTRG.12931.2 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding   34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 1.7438541 1.2567653 1.3419120 0.2054864 0.5047714 0.09385203 0.05430000 0.074225 0.031575 -0.042650 0.57773583 0.01534393 TRUE  
MSTRG.12931.4 ENSG00000108846 No_inf pgKDN_inf ABCC3 protein_coding   34.29802 17.59887 39.46157 1.377882 3.51327 1.164511 3.2516164 0.5011847 2.6443324 0.5011847 1.7070997 2.37643243 0.08449167 0.023875 0.077975 0.054100 0.84917295 0.01534393 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000108846 E001 0.1186381 0.0117674839 1.0000000000   17 50634777 50634810 34 + 0.072 0.000 -8.045
ENSG00000108846 E002 0.1176306 0.0116858467 1.0000000000   17 50634814 50634820 7 + 0.072 0.000 -10.823
ENSG00000108846 E003 0.3631878 0.0167241396 1.0000000000   17 50634821 50634856 36 + 0.134 0.124 -0.128
ENSG00000108846 E004 1.2152490 0.0103937515 0.7522724367 0.90241692 17 50634857 50634880 24 + 0.319 0.366 0.287
ENSG00000108846 E005 2.4482194 0.0058382880 0.1794189311 0.45454369 17 50634881 50634900 20 + 0.449 0.635 0.872
ENSG00000108846 E006 2.9304536 0.0048811954 0.2877688517 0.58127131 17 50634901 50634921 21 + 0.525 0.667 0.631
ENSG00000108846 E007 6.0854765 0.0034438623 0.4840648347 0.74835027 17 50634922 50634981 60 + 0.808 0.882 0.287
ENSG00000108846 E008 0.8517815 0.0138595335 0.6767566885 0.86599578 17 50635215 50635383 169 + 0.236 0.300 0.457
ENSG00000108846 E009 1.0794679 0.2097483325 0.5499675396 0.79462069 17 50635523 50635915 393 + 0.355 0.221 -0.936
ENSG00000108846 E010 0.8532285 0.0121849694 0.6771091536 0.86610234 17 50643549 50643661 113 + 0.236 0.300 0.457
ENSG00000108846 E011 11.4454578 0.0053010332 0.3080081763 0.60127749 17 50655832 50656008 177 + 1.047 1.133 0.312
ENSG00000108846 E012 11.4591494 0.0324209870 0.3410660279 0.63265426 17 50656702 50656827 126 + 1.118 1.012 -0.387
ENSG00000108846 E013 13.3278900 0.0310989294 0.0250085010 0.14548031 17 50657046 50657183 138 + 1.219 0.967 -0.911
ENSG00000108846 E014 10.9634377 0.0012641125 0.1185578713 0.36376271 17 50658082 50658142 61 + 1.112 0.967 -0.529
ENSG00000108846 E015 11.5984117 0.0012841956 0.4206656977 0.69988064 17 50658143 50658207 65 + 1.112 1.039 -0.266
ENSG00000108846 E016 13.1842709 0.0024940227 0.5084788357 0.76675674 17 50658435 50658496 62 + 1.158 1.100 -0.209
ENSG00000108846 E017 0.8439375 0.1139150831 0.7461289755 0.89959806 17 50658497 50658546 50 + 0.280 0.221 -0.450
ENSG00000108846 E018 1.5649678 0.0773175362 0.4088441746 0.69106812 17 50659182 50659236 55 + 0.449 0.300 -0.866
ENSG00000108846 E019 20.1012096 0.0016765673 0.0059441876 0.05610572 17 50659237 50659368 132 + 1.373 1.173 -0.702
ENSG00000108846 E020 21.3834233 0.0007229599 0.0014314389 0.01971482 17 50660923 50661114 192 + 1.405 1.183 -0.779
ENSG00000108846 E021 0.3516386 0.0304958104 0.2898325696   17 50662152 50662259 108 + 0.188 0.000 -12.225
ENSG00000108846 E022 1.9807130 0.0598565846 0.0418720242 0.19911667 17 50663160 50663680 521 + 0.319 0.635 1.608
ENSG00000108846 E023 8.4319777 0.0016261399 0.1533778946 0.41798208 17 50663681 50663742 62 + 1.010 0.863 -0.553
ENSG00000108846 E024 14.3959251 0.0010232911 0.7221890144 0.88831736 17 50663743 50663858 116 + 1.185 1.154 -0.110
ENSG00000108846 E025 1.8032552 0.0954421470 0.5563804096 0.79865617 17 50663859 50663949 91 + 0.476 0.366 -0.587
ENSG00000108846 E026 24.1114452 0.0006090224 0.8765814568 0.95814086 17 50663950 50664111 162 + 1.383 1.389 0.021
ENSG00000108846 E027 4.8178393 0.0029869156 0.0009052145 0.01390143 17 50664112 50664721 610 + 0.570 0.952 1.550
ENSG00000108846 E028 16.3007203 0.0115771068 0.4882871903 0.75164462 17 50665153 50665245 93 + 1.247 1.183 -0.225
ENSG00000108846 E029 24.3258696 0.0007181247 0.6905204977 0.87293676 17 50667554 50667757 204 + 1.399 1.371 -0.096
ENSG00000108846 E030 5.7772077 0.0769027908 0.2129993967 0.49817474 17 50667758 50667862 105 + 0.887 0.667 -0.880
ENSG00000108846 E031 10.9321295 0.0557290162 0.8256486995 0.93687916 17 50667863 50668009 147 + 1.054 1.077 0.082
ENSG00000108846 E032 5.6252132 0.0024081345 0.0801357306 0.29058318 17 50668430 50668517 88 + 0.728 0.918 0.746
ENSG00000108846 E033 4.8206857 0.0029154857 0.3048224002 0.59808348 17 50668853 50668919 67 + 0.796 0.667 -0.527
ENSG00000108846 E034 7.4892497 0.0257251317 0.3972627375 0.68147512 17 50669140 50669266 127 + 0.953 0.843 -0.419
ENSG00000108846 E035 8.8421615 0.0016148097 0.9343064348 0.98106717 17 50669352 50669528 177 + 0.978 0.983 0.017
ENSG00000108846 E036 2.1838771 0.0099906236 0.7485338285 0.90071851 17 50672971 50672971 1 + 0.476 0.521 0.220
ENSG00000108846 E037 4.7778408 0.0030026771 0.0413853078 0.19757269 17 50672972 50673024 53 + 0.647 0.882 0.946
ENSG00000108846 E038 7.5533436 0.0020320188 0.1758121493 0.44999320 17 50673025 50673138 114 + 0.865 0.997 0.497
ENSG00000108846 E039 0.0000000       17 50673139 50673169 31 +      
ENSG00000108846 E040 8.0063023 0.0018083094 0.8383539492 0.94210680 17 50673469 50673614 146 + 0.935 0.952 0.064
ENSG00000108846 E041 4.3339921 0.0485541920 0.2697536424 0.56334381 17 50673615 50673658 44 + 0.770 0.600 -0.714
ENSG00000108846 E042 0.1187032 0.0117280432 1.0000000000   17 50674216 50674450 235 + 0.072 0.000 -10.823
ENSG00000108846 E043 6.8753623 0.0147226180 0.3044059351 0.59779456 17 50675362 50675476 115 + 0.925 0.799 -0.486
ENSG00000108846 E044 1.5831013 0.0124357775 0.8015068561 0.92592094 17 50675631 50675653 23 + 0.389 0.424 0.193
ENSG00000108846 E045 7.3092318 0.0385551953 0.0565906104 0.23739270 17 50675654 50675775 122 + 0.986 0.725 -1.013
ENSG00000108846 E046 15.5477495 0.0013947823 0.1199155622 0.36601731 17 50675883 50676090 208 + 1.247 1.122 -0.443
ENSG00000108846 E047 13.8474518 0.0038665318 0.4617608662 0.73231624 17 50676278 50676453 176 + 1.136 1.192 0.202
ENSG00000108846 E048 11.7805688 0.0356356146 0.6891068981 0.87207967 17 50676454 50676588 135 + 1.074 1.122 0.175
ENSG00000108846 E049 13.2423295 0.0192188684 0.5307375444 0.78163231 17 50677744 50677943 200 + 1.118 1.173 0.198
ENSG00000108846 E050 4.1997085 0.0038580982 0.0018214000 0.02374556 17 50677944 50678092 149 + 0.525 0.901 1.563
ENSG00000108846 E051 10.6363076 0.0013250130 0.5099398653 0.76755684 17 50678093 50678219 127 + 1.074 1.012 -0.228
ENSG00000108846 E052 3.5607266 0.0047232327 0.0300059643 0.16302424 17 50678220 50678681 462 + 0.525 0.799 1.171
ENSG00000108846 E053 10.6724861 0.0014130060 0.0007844547 0.01242549 17 50678899 50679797 899 + 0.925 1.210 1.038
ENSG00000108846 E054 10.0882116 0.0013968309 0.3864655003 0.67235543 17 50679798 50679899 102 + 1.002 1.076 0.272
ENSG00000108846 E055 12.1538230 0.0056255802 0.4436949507 0.71843570 17 50683610 50683756 147 + 1.081 1.143 0.226
ENSG00000108846 E056 20.3621929 0.0066113263 0.0394697655 0.19256104 17 50683949 50684107 159 + 1.256 1.401 0.507
ENSG00000108846 E057 21.6427608 0.0007231759 0.4350135105 0.71194109 17 50684709 50684875 167 + 1.360 1.305 -0.189
ENSG00000108846 E058 0.3720293 0.0167329641 0.2744939846   17 50687309 50687412 104 + 0.072 0.221 1.872
ENSG00000108846 E059 0.4886249 0.0161757486 0.5450625027   17 50687413 50687535 123 + 0.134 0.221 0.872
ENSG00000108846 E060 24.4154606 0.0006501318 0.3682889025 0.65678036 17 50687536 50687730 195 + 1.411 1.353 -0.204
ENSG00000108846 E061 0.3516386 0.0304958104 0.2898325696   17 50688411 50688475 65 + 0.188 0.000 -12.225
ENSG00000108846 E062 48.2167166 0.0003373737 0.0028351854 0.03309803 17 50691092 50692253 1162 + 1.628 1.750 0.416

Help

Please Click HERE to learn more details about the results from DEXseq.