ENSG00000109103

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301032 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding protein_coding 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 9.330188 6.341931 9.487577 0.4356384 1.0369412 0.5803642 0.16202500 0.129275 0.166500 0.037225 8.133520e-01 1.569138e-10 FALSE TRUE
ENST00000335765 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding protein_coding 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 31.357842 26.217154 35.043042 1.2396583 1.8947904 0.4184784 0.55680000 0.531200 0.625650 0.094450 6.720531e-01 1.569138e-10 FALSE TRUE
ENST00000470125 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding protein_coding 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 2.500958 5.874001 0.000000 0.2174198 0.0000000 -9.2006538 0.04835000 0.119675 0.000000 -0.119675 1.569138e-10 1.569138e-10 FALSE FALSE
ENST00000484980 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding protein_coding 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 2.764794 0.000000 3.682036 0.0000000 0.1699875 8.5282729 0.04617500 0.000000 0.066175 0.066175 1.538698e-06 1.569138e-10 FALSE TRUE
ENST00000487844 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding retained_intron 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 6.582418 7.044904 5.041367 2.3534689 5.0413666 -0.4819528 0.10863333 0.136675 0.069225 -0.067450 1.124735e-01 1.569138e-10 FALSE FALSE
ENST00000578434 ENSG00000109103 No_inf pgKDN_inf UNC119 protein_coding retained_intron 56.91887 49.56706 57.27789 2.563392 5.250578 0.2085577 3.981115 4.089064 2.819195 0.9121403 1.7850504 -0.5349029 0.07081667 0.083100 0.050950 -0.032150 6.485706e-01 1.569138e-10 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000109103 E001 0.5923132 0.0157833708 1.820231e-02 1.191556e-01 17 28546708 28546710 3 - 0.352 0.000 -10.820
ENSG00000109103 E002 1.5820252 0.0287406191 3.837627e-01 6.698601e-01 17 28546711 28546749 39 - 0.477 0.343 -0.734
ENSG00000109103 E003 156.6612815 0.0001453898 1.555840e-01 4.215024e-01 17 28546750 28547409 660 - 2.211 2.184 -0.092
ENSG00000109103 E004 12.2390660 0.0011435277 2.021665e-02 1.278777e-01 17 28547410 28547523 114 - 1.010 1.201 0.689
ENSG00000109103 E005 11.6859764 0.0014889518 3.539167e-01 6.436302e-01 17 28547524 28547641 118 - 1.060 1.137 0.280
ENSG00000109103 E006 4.8036045 0.0034400636 3.236956e-01 6.163604e-01 17 28547642 28547676 35 - 0.698 0.814 0.468
ENSG00000109103 E007 18.4949772 0.0011809437 9.947641e-01 1.000000e+00 17 28547677 28547687 11 - 1.289 1.290 0.002
ENSG00000109103 E008 53.9528581 0.0004822618 2.335976e-01 5.224706e-01 17 28547688 28547849 162 - 1.763 1.717 -0.154
ENSG00000109103 E009 38.2382839 0.0004736265 1.118766e-01 3.513014e-01 17 28547999 28548101 103 - 1.630 1.557 -0.250
ENSG00000109103 E010 2.2213203 0.2179029182 3.834435e-01 6.695364e-01 17 28548102 28548173 72 - 0.439 0.561 0.597
ENSG00000109103 E011 29.7989163 0.0005399302 1.716838e-01 4.443184e-01 17 28548592 28548656 65 - 1.524 1.453 -0.245
ENSG00000109103 E012 22.3814048 0.0007208739 7.712994e-03 6.745454e-02 17 28548657 28548705 49 - 1.446 1.284 -0.563
ENSG00000109103 E013 78.0743517 0.0003383444 1.062273e-12 1.380244e-10 17 28548706 28551802 3097 - 1.759 1.992 0.786
ENSG00000109103 E014 5.2100000 0.1115574203 1.302092e-01 3.828338e-01 17 28551825 28552064 240 - 0.653 0.888 0.943
ENSG00000109103 E015 2.4636371 0.2257417695 6.485902e-01 8.516596e-01 17 28552065 28552092 28 - 0.512 0.561 0.232
ENSG00000109103 E016 34.7516885 0.0004228135 1.045147e-04 2.461527e-03 17 28552338 28552631 294 - 1.643 1.453 -0.649

Help

Please Click HERE to learn more details about the results from DEXseq.