ENSG00000109572

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000347613 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding protein_coding 25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 1.686050 0.5808968 1.6104721 0.5808968 1.6104721 1.4554361 0.08295000 0.008950 0.071225 0.062275 9.740921e-01 6.71995e-06 FALSE TRUE
ENST00000360642 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding protein_coding 25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 2.392772 2.8430591 3.6430820 1.0316222 1.4531009 0.3566045 0.10299167 0.156475 0.118875 -0.037600 1.000000e+00 6.71995e-06 FALSE TRUE
ENST00000513761 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding protein_coding 25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 3.003174 1.4040661 2.7363651 1.4040661 1.6308707 0.9576739 0.20226667 0.124250 0.164000 0.039750 8.373490e-01 6.71995e-06 FALSE TRUE
ENST00000515420 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding protein_coding 25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 1.932008 0.0000000 1.3247750 0.0000000 1.3247750 7.0604527 0.09944167 0.000000 0.058575 0.058575 8.866860e-01 6.71995e-06 FALSE TRUE
MSTRG.22527.12 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding   25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 2.568476 5.0166019 0.8561541 0.7625156 0.8561541 -2.5368878 0.16380000 0.351975 0.037850 -0.314125 4.865756e-02 6.71995e-06 FALSE TRUE
MSTRG.22527.3 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding   25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 2.242779 0.0000000 6.0861262 0.0000000 0.6643337 9.2517490 0.10734167 0.000000 0.270250 0.270250 6.719950e-06 6.71995e-06 FALSE TRUE
MSTRG.22527.4 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding   25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 1.225486 1.5717688 1.7267490 0.9074717 0.6456278 0.1348506 0.07535833 0.125375 0.080775 -0.044600 9.954040e-01 6.71995e-06 FALSE TRUE
MSTRG.22527.8 ENSG00000109572 No_inf pgKDN_inf CLCN3 protein_coding   25.21406 25.34155 33.5534 13.21943 15.04235 0.404815 9.687759 13.4936011 15.5696752 13.4936011 15.5696752 0.2063210 0.13535000 0.207625 0.198425 -0.009200 1.000000e+00 6.71995e-06   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000109572 E001 0.0000000       4 169612633 169612677 45 +      
ENSG00000109572 E002 0.2530140 0.2653801326 1.903723e-01   4 169620529 169620546 18 + 0.000 0.205 9.944
ENSG00000109572 E003 0.3700180 0.2299481590 4.419003e-01   4 169620547 169620551 5 + 0.079 0.205 1.606
ENSG00000109572 E004 0.6138760 0.1740105783 4.353027e-01 0.712198302 4 169620552 169620577 26 + 0.145 0.280 1.191
ENSG00000109572 E005 3.2472305 0.0046558530 9.948078e-02 0.329506216 4 169620578 169620682 105 + 0.696 0.493 -0.909
ENSG00000109572 E006 13.1901922 0.0015186521 1.191606e-01 0.364825660 4 169620683 169621063 381 + 1.184 1.085 -0.355
ENSG00000109572 E007 4.7812669 0.0113221860 2.305750e-01 0.519005640 4 169635913 169635982 70 + 0.679 0.847 0.679
ENSG00000109572 E008 8.1370856 0.0046457195 6.905745e-01 0.872974256 4 169635983 169636088 106 + 0.961 0.947 -0.052
ENSG00000109572 E009 0.3719991 0.0168075587 3.878749e-01   4 169642708 169643168 461 + 0.079 0.205 1.605
ENSG00000109572 E010 0.1265070 0.0123249631 3.744270e-01   4 169644287 169644304 18 + 0.000 0.115 11.542
ENSG00000109572 E011 0.0000000       4 169660240 169660448 209 +      
ENSG00000109572 E012 3.5042315 0.0942936572 4.007795e-01 0.684104260 4 169680050 169680067 18 + 0.696 0.570 -0.546
ENSG00000109572 E013 8.9345997 0.0134061416 1.015685e-01 0.332819314 4 169680068 169680207 140 + 1.046 0.900 -0.543
ENSG00000109572 E014 0.0000000       4 169680379 169680731 353 +      
ENSG00000109572 E015 9.5980769 0.0028148527 8.966539e-01 0.965963091 4 169687658 169687757 100 + 1.014 1.028 0.051
ENSG00000109572 E016 13.6734506 0.0010373146 1.419847e-01 0.400911214 4 169689043 169689230 188 + 1.195 1.106 -0.318
ENSG00000109572 E017 6.4952367 0.1013844371 9.064829e-02 0.312704841 4 169690530 169690600 71 + 0.951 0.718 -0.909
ENSG00000109572 E018 6.5206328 0.0025809763 7.921414e-02 0.288634335 4 169690601 169690652 52 + 0.931 0.766 -0.642
ENSG00000109572 E019 14.8934161 0.0010429859 1.054530e-01 0.339753958 4 169692114 169692320 207 + 1.232 1.136 -0.342
ENSG00000109572 E020 4.9259185 0.0246116285 3.963624e-02 0.193006605 4 169695612 169695630 19 + 0.854 0.604 -1.026
ENSG00000109572 E021 8.9344495 0.0019519355 7.304138e-02 0.274568582 4 169695631 169695692 62 + 1.046 0.900 -0.543
ENSG00000109572 E022 7.8753137 0.0026795112 3.384884e-01 0.630232335 4 169697189 169697279 91 + 0.970 0.900 -0.263
ENSG00000109572 E023 8.4786422 0.0109422208 2.682903e-01 0.561831531 4 169697280 169697360 81 + 1.006 0.916 -0.333
ENSG00000109572 E024 31.3591648 0.0004653865 2.881745e-02 0.159066648 4 169697361 169697734 374 + 1.538 1.450 -0.303
ENSG00000109572 E025 16.2923763 0.0010247727 9.615962e-01 0.991620253 4 169703998 169704184 187 + 1.222 1.246 0.083
ENSG00000109572 E026 43.3836334 0.0164733604 8.282082e-01 0.937744946 4 169706868 169707266 399 + 1.636 1.648 0.041
ENSG00000109572 E027 22.3695364 0.0161668910 6.555344e-01 0.855585790 4 169713079 169713295 217 + 1.366 1.357 -0.032
ENSG00000109572 E028 2.8107806 0.0053409258 5.302320e-01 0.781374657 4 169717792 169717867 76 + 0.529 0.636 0.480
ENSG00000109572 E029 272.2806895 0.0044386266 6.546718e-05 0.001660041 4 169719907 169723673 3767 + 2.385 2.487 0.343

Help

Please Click HERE to learn more details about the results from DEXseq.