ENSG00000109606

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336812 ENSG00000109606 No_inf pgKDN_inf DHX15 protein_coding protein_coding 89.05704 65.27683 103.496 3.941692 2.694483 0.66485 64.468289 36.276559 84.078188 1.211501 1.5141865 1.21246789 0.70620000 0.563300 0.812925 0.249625 7.091029e-06 7.091029e-06 FALSE TRUE
ENST00000508032 ENSG00000109606 No_inf pgKDN_inf DHX15 protein_coding protein_coding_CDS_not_defined 89.05704 65.27683 103.496 3.941692 2.694483 0.66485 4.900521 6.944501 3.999032 1.582725 0.4159364 -0.79469307 0.06235833 0.111200 0.038750 -0.072450 3.483911e-01 7.091029e-06 FALSE TRUE
ENST00000508368 ENSG00000109606 No_inf pgKDN_inf DHX15 protein_coding protein_coding_CDS_not_defined 89.05704 65.27683 103.496 3.941692 2.694483 0.66485 2.892065 6.179778 0.000000 5.365823 0.0000000 -9.27374397 0.03562500 0.082375 0.000000 -0.082375 4.060063e-01 7.091029e-06   FALSE
MSTRG.21603.2 ENSG00000109606 No_inf pgKDN_inf DHX15 protein_coding   89.05704 65.27683 103.496 3.941692 2.694483 0.66485 10.141514 9.947793 10.087570 1.390476 0.7528144 0.02011019 0.11846667 0.151050 0.097450 -0.053600 4.795295e-01 7.091029e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000109606 E001 0.3617709 1.663639e-02 8.785091e-01   4 24517441 24517652 212 - 0.146 0.114 -0.402
ENSG00000109606 E002 1.2077207 2.297680e-01 6.739539e-01 8.649499e-01 4 24527475 24527476 2 - 0.379 0.279 -0.627
ENSG00000109606 E003 71.5377517 2.205915e-04 4.906978e-01 7.532353e-01 4 24527477 24527713 237 - 1.865 1.839 -0.087
ENSG00000109606 E004 65.7251192 2.508420e-04 4.102215e-01 6.921528e-01 4 24527714 24527759 46 - 1.805 1.835 0.100
ENSG00000109606 E005 183.6545904 9.981844e-05 9.730142e-01 9.950279e-01 4 24527760 24528041 282 - 2.261 2.259 -0.006
ENSG00000109606 E006 117.4515403 1.616096e-04 6.207727e-01 8.361200e-01 4 24529601 24529770 170 - 2.073 2.059 -0.050
ENSG00000109606 E007 5.5897578 3.429657e-02 7.784296e-04 1.236273e-02 4 24529771 24530883 1113 - 0.578 1.014 1.743
ENSG00000109606 E008 116.0793784 2.398041e-03 9.984213e-01 1.000000e+00 4 24532864 24533054 191 - 2.062 2.062 -0.001
ENSG00000109606 E009 5.4350118 3.077358e-03 4.436711e-03 4.557586e-02 4 24533055 24534199 1145 - 0.642 0.960 1.264
ENSG00000109606 E010 71.7113511 2.709469e-04 2.066440e-01 4.902841e-01 4 24537051 24537165 115 - 1.874 1.827 -0.157
ENSG00000109606 E011 29.7106765 4.675440e-04 2.735634e-01 5.673230e-01 4 24537166 24537173 8 - 1.506 1.444 -0.213
ENSG00000109606 E012 202.0876489 1.475213e-04 4.751466e-52 8.542186e-49 4 24537174 24539708 2535 - 2.143 2.456 1.045
ENSG00000109606 E013 34.5960051 2.256470e-03 2.962402e-05 8.566981e-04 4 24539709 24540107 399 - 1.439 1.661 0.761
ENSG00000109606 E014 88.8723599 2.029438e-04 4.361460e-02 2.038750e-01 4 24540108 24540299 192 - 1.974 1.907 -0.224
ENSG00000109606 E015 56.3722420 2.991952e-04 8.166908e-01 9.332670e-01 4 24540840 24540948 109 - 1.757 1.746 -0.035
ENSG00000109606 E016 73.4143483 1.499780e-03 5.355310e-02 2.304236e-01 4 24541873 24542022 150 - 1.896 1.820 -0.256
ENSG00000109606 E017 61.2174270 2.388066e-04 8.525441e-02 3.019824e-01 4 24542940 24543026 87 - 1.815 1.746 -0.231
ENSG00000109606 E018 109.0192397 2.385535e-04 5.891516e-02 2.433770e-01 4 24548855 24549022 168 - 2.058 2.001 -0.189
ENSG00000109606 E019 118.7287538 1.447196e-04 1.007578e-04 2.390793e-03 4 24554725 24554943 219 - 2.115 2.004 -0.370
ENSG00000109606 E020 81.8689614 3.068105e-04 7.551255e-03 6.650382e-02 4 24556251 24556410 160 - 1.948 1.856 -0.311
ENSG00000109606 E021 72.9665339 2.129791e-04 3.281591e-02 1.717299e-01 4 24570654 24570847 194 - 1.893 1.816 -0.262
ENSG00000109606 E022 77.8517802 6.123940e-03 2.294583e-02 1.381892e-01 4 24576243 24576468 226 - 1.933 1.824 -0.367
ENSG00000109606 E023 48.1254841 4.837177e-03 1.345254e-02 9.746767e-02 4 24576469 24576549 81 - 1.735 1.603 -0.447
ENSG00000109606 E024 58.2618210 2.627942e-04 4.617938e-02 2.107560e-01 4 24576550 24576678 129 - 1.799 1.717 -0.275
ENSG00000109606 E025 0.4992916 3.130985e-02 1.626233e-01   4 24580720 24580942 223 - 0.079 0.279 2.180
ENSG00000109606 E026 0.0000000       4 24584184 24584322 139 -      
ENSG00000109606 E027 41.9781944 6.106837e-03 5.547982e-02 2.346554e-01 4 24584323 24584557 235 - 1.670 1.559 -0.378

Help

Please Click HERE to learn more details about the results from DEXseq.