ENSG00000109736

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355443 ENSG00000109736 No_inf pgKDN_inf MFSD10 protein_coding protein_coding 122.2677 91.24211 123.4693 3.87838 3.86045 0.4363391 58.683016 28.28810 75.099930 3.5116078 4.5828816 1.40829844 0.46490833 0.308100 0.609125 0.301025 1.607871e-05 1.607871e-05 FALSE TRUE
ENST00000514031 ENSG00000109736 No_inf pgKDN_inf MFSD10 protein_coding retained_intron 122.2677 91.24211 123.4693 3.87838 3.86045 0.4363391 12.489050 15.42531 8.506016 0.8131010 0.6806343 -0.85798346 0.10975833 0.170575 0.069625 -0.100950 1.424183e-02 1.607871e-05 FALSE TRUE
MSTRG.21467.1 ENSG00000109736 No_inf pgKDN_inf MFSD10 protein_coding   122.2677 91.24211 123.4693 3.87838 3.86045 0.4363391 16.764163 11.06644 11.425038 1.6825535 5.1689466 0.04596641 0.13322500 0.122650 0.094300 -0.028350 8.336667e-01 1.607871e-05 FALSE TRUE
MSTRG.21467.17 ENSG00000109736 No_inf pgKDN_inf MFSD10 protein_coding   122.2677 91.24211 123.4693 3.87838 3.86045 0.4363391 7.892151 11.14180 4.922679 0.6525744 0.6755039 -1.17683320 0.07081667 0.122450 0.039975 -0.082475 6.656980e-03 1.607871e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000109736 E001 0.3806233 0.0158434309 6.319632e-02   4 2930561 2930564 4 - 0.000 0.263 11.843
ENSG00000109736 E002 0.3806233 0.0158434309 6.319632e-02   4 2930565 2930566 2 - 0.000 0.263 11.851
ENSG00000109736 E003 1.6247951 0.0132372981 1.682505e-02 1.131124e-01 4 2930567 2930567 1 - 0.217 0.577 2.097
ENSG00000109736 E004 1.6247951 0.0132372981 1.682505e-02 1.131124e-01 4 2930568 2930568 1 - 0.217 0.577 2.097
ENSG00000109736 E005 8.6653964 0.0015286310 8.244058e-01 9.362671e-01 4 2930569 2930582 14 - 0.974 0.994 0.075
ENSG00000109736 E006 10.0102060 0.0013819501 8.042854e-01 9.273629e-01 4 2930583 2930602 20 - 1.030 1.052 0.078
ENSG00000109736 E007 10.6274455 0.0012881944 6.785431e-01 8.670204e-01 4 2930603 2930604 2 - 1.047 1.082 0.127
ENSG00000109736 E008 14.3906763 0.0014212068 9.458049e-01 9.854120e-01 4 2930605 2930610 6 - 1.184 1.188 0.016
ENSG00000109736 E009 158.8234517 0.0025801404 5.017926e-01 7.615855e-01 4 2930611 2930953 343 - 2.211 2.191 -0.068
ENSG00000109736 E010 14.2057620 0.0018772454 1.851470e-01 4.626903e-01 4 2930954 2931060 107 - 1.131 1.233 0.360
ENSG00000109736 E011 80.2970189 0.0002016382 7.313198e-01 8.932539e-01 4 2931061 2931139 79 - 1.914 1.902 -0.041
ENSG00000109736 E012 46.1847239 0.0003679488 8.509747e-01 9.472419e-01 4 2931140 2931150 11 - 1.676 1.667 -0.031
ENSG00000109736 E013 2.6132897 0.0836314974 3.449393e-02 1.773819e-01 4 2931151 2931226 76 - 0.361 0.713 1.683
ENSG00000109736 E014 65.3130113 0.0050456911 4.160820e-01 6.960013e-01 4 2931227 2931274 48 - 1.802 1.840 0.128
ENSG00000109736 E015 82.6918079 0.0002030558 6.151648e-01 8.329668e-01 4 2931375 2931465 91 - 1.914 1.930 0.053
ENSG00000109736 E016 2.1061802 0.0069876434 8.699462e-02 3.056258e-01 4 2931466 2931554 89 - 0.361 0.607 1.235
ENSG00000109736 E017 90.1078067 0.0012305042 4.608008e-01 7.319790e-01 4 2931555 2931653 99 - 1.970 1.943 -0.088
ENSG00000109736 E018 39.6039344 0.0039708457 9.966020e-01 1.000000e+00 4 2931654 2931663 10 - 1.608 1.606 -0.006
ENSG00000109736 E019 8.2704986 0.0016651851 4.567484e-03 4.647975e-02 4 2931664 2931824 161 - 0.821 1.092 1.017
ENSG00000109736 E020 94.9822349 0.0027696719 9.301347e-01 9.794978e-01 4 2931825 2931936 112 - 1.980 1.982 0.006
ENSG00000109736 E021 3.4466505 0.0040699235 1.599798e-01 4.275271e-01 4 2931937 2932044 108 - 0.555 0.735 0.775
ENSG00000109736 E022 49.7265863 0.0029350439 8.318765e-01 9.392783e-01 4 2932045 2932064 20 - 1.709 1.697 -0.038
ENSG00000109736 E023 82.2326740 0.0002030113 6.203944e-01 8.358609e-01 4 2932065 2932153 89 - 1.926 1.909 -0.057
ENSG00000109736 E024 68.7446506 0.0008215644 9.127935e-01 9.722975e-01 4 2932351 2932409 59 - 1.841 1.844 0.011
ENSG00000109736 E025 87.0392801 0.0001848421 3.625021e-02 1.828923e-01 4 2932410 2932512 103 - 1.973 1.905 -0.228
ENSG00000109736 E026 64.4522395 0.0004916341 6.368796e-01 8.449536e-01 4 2932600 2932690 91 - 1.823 1.804 -0.063
ENSG00000109736 E027 52.7961514 0.0003164208 1.772467e-01 4.517782e-01 4 2932691 2932758 68 - 1.754 1.697 -0.192
ENSG00000109736 E028 6.2053883 0.0022175009 6.308399e-04 1.043993e-02 4 2932759 2932795 37 - 0.649 1.018 1.448
ENSG00000109736 E029 19.4304045 0.0006819865 1.590191e-13 2.293192e-11 4 2932796 2933105 310 - 1.003 1.513 1.801
ENSG00000109736 E030 49.9551541 0.0002972099 6.616386e-01 8.587567e-01 4 2933106 2933177 72 - 1.714 1.695 -0.065
ENSG00000109736 E031 33.5946517 0.0004399637 3.525896e-01 6.426471e-01 4 2933178 2933209 32 - 1.515 1.562 0.160
ENSG00000109736 E032 51.5584627 0.0004074339 9.941962e-01 1.000000e+00 4 2933567 2933663 97 - 1.719 1.719 -0.003
ENSG00000109736 E033 65.0599833 0.0045440042 1.589657e-02 1.093160e-01 4 2933753 2933944 192 - 1.866 1.754 -0.377
ENSG00000109736 E034 11.1189966 0.0012409323 5.047465e-01 7.638067e-01 4 2933945 2934458 514 - 1.056 1.111 0.201
ENSG00000109736 E035 12.8085843 0.0302180943 4.922126e-02 2.187278e-01 4 2934769 2934839 71 - 1.225 1.006 -0.786

Help

Please Click HERE to learn more details about the results from DEXseq.