ENSG00000110057

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000227471 ENSG00000110057 No_inf pgKDN_inf UNC93B1 protein_coding protein_coding 129.6168 65.60987 146.7142 2.286093 2.674 1.160902 112.4783 51.464 134.2724 1.542445 2.351149 1.383355 0.85335 0.785025 0.915375 0.13035 5.253237e-07 5.253237e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110057 E001 290.5256137 0.0003674223 4.291370e-01 7.075624e-01 11 67991100 67991817 718 - 2.448 2.432 -0.052
ENSG00000110057 E002 21.9187016 0.0017071198 1.030540e-01 3.355332e-01 11 67991818 67991857 40 - 1.375 1.260 -0.399
ENSG00000110057 E003 27.6842712 0.0057197174 1.251166e-01 3.749727e-01 11 67993676 67993794 119 - 1.470 1.364 -0.365
ENSG00000110057 E004 140.5095083 0.0001269380 9.212567e-02 3.152532e-01 11 67995611 67995884 274 - 2.144 2.098 -0.153
ENSG00000110057 E005 0.3628408 0.0167138052 1.000000e+00   11 67995885 67995980 96 - 0.127 0.131 0.041
ENSG00000110057 E006 130.6476835 0.0001529930 6.519799e-01 8.534423e-01 11 67996602 67996784 183 - 2.102 2.088 -0.046
ENSG00000110057 E007 2.8302278 0.0050093612 2.025408e-02 1.279887e-01 11 67997558 67997674 117 - 0.432 0.745 1.420
ENSG00000110057 E008 60.4744661 0.0003467810 3.624050e-01 6.516186e-01 11 67997675 67997718 44 - 1.780 1.741 -0.131
ENSG00000110057 E009 83.6230269 0.0004277899 3.937243e-01 6.786120e-01 11 67997719 67997799 81 - 1.896 1.924 0.094
ENSG00000110057 E010 53.7471641 0.0002938117 3.060153e-02 1.645964e-01 11 67998359 67998376 18 - 1.684 1.773 0.303
ENSG00000110057 E011 49.5338262 0.0003159511 1.665507e-02 1.125273e-01 11 67998377 67998386 10 - 1.643 1.746 0.350
ENSG00000110057 E012 83.5012846 0.0003404809 8.562859e-02 3.028190e-01 11 67998387 67998452 66 - 1.884 1.941 0.193
ENSG00000110057 E013 45.4128752 0.0003596180 4.583199e-01 7.302565e-01 11 67999173 67999175 3 - 1.657 1.620 -0.123
ENSG00000110057 E014 105.3439865 0.0001588637 4.348670e-01 7.119051e-01 11 67999176 67999305 130 - 2.013 1.988 -0.084
ENSG00000110057 E015 6.3231482 0.0023189060 9.137208e-07 4.307926e-05 11 67999306 67999375 70 - 0.591 1.112 2.041
ENSG00000110057 E016 7.9230813 0.0017461666 3.642780e-07 1.864039e-05 11 67999376 67999518 143 - 0.692 1.187 1.875
ENSG00000110057 E017 93.6827772 0.0035709005 3.418216e-01 6.332935e-01 11 67999519 67999680 162 - 1.967 1.927 -0.135
ENSG00000110057 E018 87.7674716 0.0066485125 3.691564e-01 6.574454e-01 11 68003022 68003175 154 - 1.940 1.897 -0.144
ENSG00000110057 E019 7.7121070 0.0017977405 7.088634e-03 6.359254e-02 11 68003176 68003656 481 - 0.810 1.075 0.996
ENSG00000110057 E020 65.7631335 0.0017817091 9.701561e-01 9.939668e-01 11 68003657 68003798 142 - 1.804 1.800 -0.011
ENSG00000110057 E021 4.1544908 0.0034479406 8.498404e-02 3.014092e-01 11 68003799 68003947 149 - 0.610 0.821 0.872
ENSG00000110057 E022 36.7233572 0.0003810038 5.233018e-01 7.766548e-01 11 68003948 68004107 160 - 1.566 1.532 -0.118
ENSG00000110057 E023 0.1272623 0.0122409137 2.452651e-01   11 68004807 68004982 176 - 0.000 0.131 10.029

Help

Please Click HERE to learn more details about the results from DEXseq.