ENSG00000110074

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263578 ENSG00000110074 No_inf pgKDN_inf FOXRED1 protein_coding protein_coding 21.92398 22.80711 19.24257 1.309146 0.6358644 -0.2450649 7.137488 3.082700 12.5330168 1.8534116 1.0089087 2.0199457 0.34654167 0.148600 0.652625 0.504025 0.07819605 0.02876312 FALSE TRUE
ENST00000532590 ENSG00000110074 No_inf pgKDN_inf FOXRED1 protein_coding retained_intron 21.92398 22.80711 19.24257 1.309146 0.6358644 -0.2450649 2.219011 4.200529 0.0000000 1.6671676 0.0000000 -8.7178578 0.09137500 0.173375 0.000000 -0.173375 0.02876312 0.02876312   FALSE
ENST00000685484 ENSG00000110074 No_inf pgKDN_inf FOXRED1 protein_coding protein_coding 21.92398 22.80711 19.24257 1.309146 0.6358644 -0.2450649 1.927983 2.924312 1.9032069 0.4368655 0.3833123 -0.6170295 0.08912500 0.128150 0.097875 -0.030275 0.84422772 0.02876312 FALSE TRUE
ENST00000687786 ENSG00000110074 No_inf pgKDN_inf FOXRED1 protein_coding retained_intron 21.92398 22.80711 19.24257 1.309146 0.6358644 -0.2450649 2.787835 4.003372 1.7947941 0.2559402 0.1397737 -1.1529807 0.12658333 0.175700 0.093450 -0.082250 0.44253579 0.02876312 FALSE TRUE
ENST00000688100 ENSG00000110074 No_inf pgKDN_inf FOXRED1 protein_coding retained_intron 21.92398 22.80711 19.24257 1.309146 0.6358644 -0.2450649 1.137101 1.828060 0.7857259 0.3602467 0.1453075 -1.2078405 0.05233333 0.081775 0.040250 -0.041525 0.69926449 0.02876312 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110074 E001 0.0000000       11 126269024 126269028 5 +      
ENSG00000110074 E002 0.0000000       11 126269029 126269054 26 +      
ENSG00000110074 E003 0.0000000       11 126269055 126269134 80 +      
ENSG00000110074 E004 0.0000000       11 126269135 126269147 13 +      
ENSG00000110074 E005 0.0000000       11 126269148 126269153 6 +      
ENSG00000110074 E006 0.1176306 0.0118536642 4.477364e-01   11 126269154 126269156 3 + 0.103 0.000 -9.334
ENSG00000110074 E007 0.2363338 0.0156585163 1.862490e-01   11 126269157 126269161 5 + 0.186 0.000 -12.889
ENSG00000110074 E008 0.3631878 0.0165358164 4.770815e-01   11 126269162 126269162 1 + 0.186 0.088 -1.258
ENSG00000110074 E009 0.8423409 0.0125848486 1.685769e-01 0.4398822202 11 126269163 126269170 8 + 0.369 0.161 -1.580
ENSG00000110074 E010 1.9211145 0.0342960106 2.414513e-02 0.1423527830 11 126269171 126269189 19 + 0.625 0.278 -1.843
ENSG00000110074 E011 2.5362464 0.0208220204 6.296501e-02 0.2523674942 11 126269190 126269190 1 + 0.676 0.409 -1.258
ENSG00000110074 E012 3.0362022 0.0053510030 1.509868e-01 0.4139550868 11 126269191 126269191 1 + 0.700 0.510 -0.843
ENSG00000110074 E013 3.1549054 0.0055873224 1.056528e-01 0.3401348116 11 126269192 126269193 2 + 0.723 0.510 -0.937
ENSG00000110074 E014 4.2430831 0.0060740653 4.328366e-02 0.2028473440 11 126269194 126269206 13 + 0.838 0.592 -1.017
ENSG00000110074 E015 7.6460204 0.0172032527 2.029250e-02 0.1280663973 11 126269207 126269246 40 + 1.058 0.804 -0.959
ENSG00000110074 E016 9.2747191 0.0020270325 9.011671e-02 0.3118387520 11 126269247 126269291 45 + 1.088 0.935 -0.563
ENSG00000110074 E017 2.4504173 0.1523998981 7.587449e-01 0.9053172357 11 126269292 126269415 124 + 0.566 0.510 -0.259
ENSG00000110074 E018 15.6903286 0.0009379520 1.666992e-05 0.0005288679 11 126270019 126270944 926 + 1.004 1.334 1.178
ENSG00000110074 E019 8.8073727 0.0034312377 4.914468e-02 0.2185841849 11 126270945 126271219 275 + 0.871 1.061 0.711
ENSG00000110074 E020 3.6292731 0.0040502919 5.667164e-03 0.0541841513 11 126271220 126271295 76 + 0.416 0.789 1.680
ENSG00000110074 E021 2.8855569 0.0050490186 4.793674e-03 0.0480885611 11 126271296 126271350 55 + 0.316 0.720 1.989
ENSG00000110074 E022 2.2580866 0.0063393935 1.034066e-02 0.0820770038 11 126271351 126271436 86 + 0.256 0.639 2.064
ENSG00000110074 E023 19.6861857 0.0092137226 1.029669e-01 0.3353917325 11 126271437 126271657 221 + 1.376 1.255 -0.420
ENSG00000110074 E024 0.7511446 0.0147742594 1.419765e-01 0.4009088956 11 126271658 126271718 61 + 0.103 0.326 2.064
ENSG00000110074 E025 1.3711205 0.0095295563 2.190957e-01 0.5057438649 11 126271719 126271855 137 + 0.256 0.446 1.157
ENSG00000110074 E026 0.2541163 0.0159935380 3.115479e-01   11 126271856 126271881 26 + 0.000 0.161 11.763
ENSG00000110074 E027 4.2253634 0.0654192624 2.092631e-01 0.4935302055 11 126271998 126272477 480 + 0.596 0.789 0.805
ENSG00000110074 E028 2.6239185 0.0156040927 4.705558e-02 0.2130715753 11 126272478 126272682 205 + 0.369 0.661 1.420
ENSG00000110074 E029 2.8740692 0.0806691285 4.600606e-02 0.2102700655 11 126272683 126272968 286 + 0.369 0.701 1.590
ENSG00000110074 E030 14.3283039 0.0010756677 2.804010e-01 0.5736940057 11 126272969 126273033 65 + 1.225 1.146 -0.283
ENSG00000110074 E031 10.5097560 0.0016396645 2.032026e-01 0.4857085489 11 126273034 126273079 46 + 1.115 1.008 -0.393
ENSG00000110074 E032 0.2458395 0.0163842860 8.888888e-01   11 126273080 126273083 4 + 0.103 0.088 -0.258
ENSG00000110074 E033 0.3628435 0.0165433980 4.780142e-01   11 126273084 126273088 5 + 0.186 0.088 -1.258
ENSG00000110074 E034 0.3628435 0.0165433980 4.780142e-01   11 126273089 126273090 2 + 0.186 0.088 -1.258
ENSG00000110074 E035 1.5849851 0.1678281011 5.282534e-01 0.7800574576 11 126273091 126273315 225 + 0.458 0.370 -0.481
ENSG00000110074 E036 0.7332058 0.0143309932 8.257604e-01 0.9368820586 11 126273316 126273335 20 + 0.256 0.223 -0.258
ENSG00000110074 E037 6.2184739 0.0023698301 1.799457e-01 0.4552522128 11 126273336 126273338 3 + 0.929 0.789 -0.542
ENSG00000110074 E038 15.9527428 0.0014220258 7.410839e-01 0.8972661343 11 126273339 126273454 116 + 1.239 1.216 -0.081
ENSG00000110074 E039 1.3782363 0.0120273660 5.991914e-02 0.2455869580 11 126273455 126273913 459 + 0.186 0.479 1.912
ENSG00000110074 E040 3.5833247 0.0045807696 4.157128e-01 0.6957874895 11 126273914 126274926 1013 + 0.596 0.701 0.452
ENSG00000110074 E041 5.1592710 0.0033385134 9.762826e-01 0.9960072421 11 126274927 126274930 4 + 0.784 0.789 0.017
ENSG00000110074 E042 10.2807882 0.0012934703 2.931271e-01 0.5867398954 11 126274931 126275021 91 + 1.097 1.008 -0.327
ENSG00000110074 E043 2.2387352 0.1514070082 2.632006e-01 0.5561177192 11 126275022 126275326 305 + 0.369 0.592 1.120
ENSG00000110074 E044 9.5429957 0.0015075849 3.046760e-01 0.5980636880 11 126275327 126275370 44 + 1.068 0.978 -0.332
ENSG00000110074 E045 9.8819184 0.0162961161 1.095561e-01 0.3474127762 11 126275371 126275428 58 + 1.116 0.957 -0.581
ENSG00000110074 E046 3.6169990 0.0047252788 1.848855e-02 0.1203429155 11 126275429 126275793 365 + 0.458 0.773 1.394
ENSG00000110074 E047 11.9698501 0.0011954082 8.737622e-02 0.3063878170 11 126275794 126275870 77 + 1.182 1.044 -0.495
ENSG00000110074 E048 20.0644291 0.0006909794 1.339706e-01 0.3888897506 11 126276059 126276219 161 + 1.371 1.277 -0.329
ENSG00000110074 E049 0.1268540 0.0122886334 6.446730e-01   11 126276220 126276246 27 + 0.000 0.088 10.838
ENSG00000110074 E050 8.2038467 0.0041279849 3.943150e-01 0.6791092850 11 126276394 126276421 28 + 1.004 0.924 -0.302
ENSG00000110074 E051 9.0600653 0.0016645906 4.349663e-01 0.7119309106 11 126276422 126276452 31 + 1.038 0.968 -0.258
ENSG00000110074 E052 12.7963105 0.0011927261 6.497361e-01 0.8524600453 11 126276453 126276523 71 + 1.115 1.152 0.132
ENSG00000110074 E053 0.8789749 0.2079753778 1.460794e-01 0.4070566244 11 126276912 126276997 86 + 0.103 0.370 2.327
ENSG00000110074 E054 1.5148793 0.2083596005 2.904532e-02 0.1598500054 11 126276998 126277070 73 + 0.103 0.539 3.201
ENSG00000110074 E055 8.2931990 0.0017822298 1.099620e-01 0.3480759233 11 126277071 126277073 3 + 0.871 1.026 0.583
ENSG00000110074 E056 17.5563657 0.0009939933 4.784205e-02 0.2152110991 11 126277074 126277175 102 + 1.182 1.321 0.489
ENSG00000110074 E057 4.8275356 0.0031651204 2.296362e-01 0.5182473800 11 126277176 126277434 259 + 0.676 0.819 0.578
ENSG00000110074 E058 66.3950856 0.0013112717 6.301349e-01 0.8413866518 11 126277435 126278131 697 + 1.815 1.833 0.063

Help

Please Click HERE to learn more details about the results from DEXseq.