ENSG00000110075

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265636 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding protein_coding 27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 0.630072 1.761948 0.0000000 0.5161025 0.0000000 -7.46919283 0.02551667 0.071450 0.000000 -0.071450 0.005178745 0.005178745 FALSE TRUE
ENST00000393800 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding protein_coding 27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 7.869041 2.420477 14.0602019 1.3978024 1.8959779 2.53333141 0.28498333 0.091250 0.499350 0.408100 0.052084794 0.005178745 FALSE TRUE
ENST00000525152 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding retained_intron 27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 2.753948 5.532752 0.3502384 1.6275854 0.3502384 -3.94357844 0.10189167 0.206725 0.013225 -0.193500 0.009885407 0.005178745   FALSE
ENST00000530734 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding protein_coding 27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 2.166963 0.441469 5.2358589 0.4414690 1.1743599 3.53848032 0.07636667 0.018100 0.184325 0.166225 0.021547173 0.005178745   FALSE
ENST00000531432 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding retained_intron 27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 1.537810 1.972740 0.9024533 0.4864857 0.5210333 -1.11967278 0.05750000 0.078400 0.029800 -0.048600 0.554464866 0.005178745   FALSE
MSTRG.5068.18 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding   27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 2.601968 6.242521 0.0000000 2.1886111 0.0000000 -9.28829409 0.10075833 0.244375 0.000000 -0.244375 0.012050883 0.005178745 FALSE TRUE
MSTRG.5068.3 ENSG00000110075 No_inf pgKDN_inf PPP6R3 protein_coding   27.00482 25.82537 27.94204 1.465671 1.412994 0.1136056 4.507566 3.236349 3.0822979 0.5313891 1.7408254 -0.07013884 0.17210000 0.128350 0.118600 -0.009750 0.831571842 0.005178745 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110075 E001 0.0000000       11 68460731 68460737 7 +      
ENSG00000110075 E002 0.0000000       11 68460738 68460739 2 +      
ENSG00000110075 E003 0.0000000       11 68460740 68460742 3 +      
ENSG00000110075 E004 0.3716209 0.0167138755 0.5248672841   11 68460743 68460746 4 + 0.091 0.180 1.147
ENSG00000110075 E005 0.3716209 0.0167138755 0.5248672841   11 68460747 68460747 1 + 0.091 0.180 1.147
ENSG00000110075 E006 0.3716209 0.0167138755 0.5248672841   11 68460748 68460748 1 + 0.091 0.180 1.147
ENSG00000110075 E007 0.3716209 0.0167138755 0.5248672841   11 68460749 68460751 3 + 0.091 0.180 1.147
ENSG00000110075 E008 0.3716209 0.0167138755 0.5248672841   11 68460752 68460754 3 + 0.091 0.180 1.147
ENSG00000110075 E009 0.6252643 0.0148576927 0.1421902454 0.401177844 11 68460755 68460769 15 + 0.091 0.308 2.147
ENSG00000110075 E010 2.7814062 0.0064849717 0.1001224747 0.330619332 11 68460770 68460812 43 + 0.674 0.448 -1.046
ENSG00000110075 E011 3.3984920 0.0085195759 0.2180957741 0.504558722 11 68460813 68460827 15 + 0.715 0.553 -0.701
ENSG00000110075 E012 1.2171680 0.0184441583 0.6374997524 0.845349781 11 68505145 68505200 56 + 0.379 0.308 -0.438
ENSG00000110075 E013 0.8433759 0.0125733389 0.3098146105 0.603080131 11 68505201 68505207 7 + 0.335 0.180 -1.175
ENSG00000110075 E014 1.4778635 0.0085923474 0.4600459271 0.731532432 11 68505208 68505249 42 + 0.335 0.448 0.632
ENSG00000110075 E015 1.3496547 0.0100270421 0.6466659338 0.850387148 11 68505250 68505271 22 + 0.335 0.406 0.410
ENSG00000110075 E016 0.3642603 0.2209969013 0.6974413655   11 68515028 68515163 136 + 0.166 0.100 -0.854
ENSG00000110075 E017 0.1268540 0.0124215180 0.4880336035   11 68515164 68515166 3 + 0.000 0.100 8.896
ENSG00000110075 E018 4.0107611 0.0037885208 0.3510284602 0.641356709 11 68519501 68519505 5 + 0.752 0.638 -0.475
ENSG00000110075 E019 6.0957979 0.0026487243 0.6180044924 0.834705356 11 68519506 68519562 57 + 0.876 0.824 -0.201
ENSG00000110075 E020 7.1783159 0.0152358302 0.4695012318 0.737521973 11 68519563 68519634 72 + 0.950 0.872 -0.296
ENSG00000110075 E021 3.7603318 0.0041681084 0.3268258417 0.619274345 11 68519635 68519651 17 + 0.734 0.612 -0.516
ENSG00000110075 E022 0.3724075 0.0167275852 0.5249309279   11 68522494 68522689 196 + 0.091 0.180 1.147
ENSG00000110075 E023 0.0000000       11 68535411 68535532 122 +      
ENSG00000110075 E024 6.0069839 0.0031210382 0.0007049617 0.011402400 11 68537659 68537714 56 + 0.993 0.612 -1.516
ENSG00000110075 E025 8.8439215 0.0016579252 0.0224139423 0.136143483 11 68537715 68537815 101 + 1.085 0.871 -0.794
ENSG00000110075 E026 9.0138587 0.0016507665 0.4592957607 0.731047468 11 68537816 68537891 76 + 1.032 0.966 -0.245
ENSG00000110075 E027 14.5408266 0.0049024228 0.9466887959 0.985784993 11 68544838 68545024 187 + 1.188 1.195 0.026
ENSG00000110075 E028 10.6892038 0.0122104614 0.1303170659 0.382980626 11 68548067 68548204 138 + 1.132 0.989 -0.521
ENSG00000110075 E029 0.3731018 0.0167051500 0.5249882983   11 68550990 68551120 131 + 0.091 0.180 1.147
ENSG00000110075 E030 7.7413270 0.0020956408 0.0178360916 0.117615921 11 68551121 68551186 66 + 1.042 0.807 -0.887
ENSG00000110075 E031 0.0000000       11 68551187 68551220 34 +      
ENSG00000110075 E032 11.7536587 0.0013122377 0.0133653219 0.097030274 11 68554145 68554257 113 + 1.195 0.989 -0.743
ENSG00000110075 E033 2.8621121 0.0990413962 0.0823734105 0.295570988 11 68558196 68558565 370 + 0.420 0.709 1.338
ENSG00000110075 E034 11.6906968 0.0012985756 0.3431232838 0.634424230 11 68558566 68558641 76 + 1.140 1.063 -0.277
ENSG00000110075 E035 7.2207699 0.0057984786 0.6264395086 0.839482024 11 68558642 68558679 38 + 0.889 0.941 0.196
ENSG00000110075 E036 12.2753904 0.0013043815 0.2007103834 0.482802470 11 68564303 68564423 121 + 1.068 1.173 0.378
ENSG00000110075 E037 3.9574976 0.0035439580 0.0932642542 0.317417447 11 68564424 68564432 9 + 0.579 0.789 0.884
ENSG00000110075 E038 0.1186381 0.0118681617 0.5927066829   11 68566999 68567013 15 + 0.091 0.000 -9.532
ENSG00000110075 E039 18.5535690 0.0008437942 0.5919548350 0.819784108 11 68567014 68567166 153 + 1.308 1.273 -0.120
ENSG00000110075 E040 17.6131128 0.0011003684 0.0309981045 0.165812096 11 68569748 68569897 150 + 1.337 1.188 -0.521
ENSG00000110075 E041 12.8021724 0.0011365367 0.4426475376 0.717921221 11 68571040 68571098 59 + 1.168 1.109 -0.212
ENSG00000110075 E042 7.0970298 0.0019700334 0.9141469641 0.972928075 11 68571099 68571104 6 + 0.902 0.914 0.047
ENSG00000110075 E043 0.0000000       11 68571105 68571216 112 +      
ENSG00000110075 E044 19.4531708 0.0007286661 0.0541351552 0.231591959 11 68574109 68574224 116 + 1.368 1.243 -0.438
ENSG00000110075 E045 15.5544037 0.0009226528 0.0535551105 0.230423647 11 68575958 68576043 86 + 1.282 1.142 -0.495
ENSG00000110075 E046 12.3230834 0.0063490807 0.7030587850 0.879194336 11 68583043 68583129 87 + 1.140 1.109 -0.111
ENSG00000110075 E047 4.7390451 0.0060728059 0.0004030859 0.007352076 11 68586276 68587797 1522 + 0.490 0.928 1.835
ENSG00000110075 E048 1.5072890 0.0253320739 0.0127261796 0.093920877 11 68587798 68587926 129 + 0.166 0.553 2.469
ENSG00000110075 E049 5.8958557 0.0486192508 0.3177501257 0.610485013 11 68587927 68587944 18 + 0.769 0.901 0.511
ENSG00000110075 E050 6.9975324 0.0021002186 0.3074176068 0.600616630 11 68587945 68587977 33 + 0.848 0.953 0.401
ENSG00000110075 E051 11.1734101 0.0013143524 0.2329039724 0.521567964 11 68587978 68588024 47 + 1.032 1.134 0.369
ENSG00000110075 E052 11.2511022 0.0013624603 0.9590183028 0.990344129 11 68590660 68590714 55 + 1.085 1.091 0.021
ENSG00000110075 E053 19.2334613 0.0020089308 0.1526161485 0.416706290 11 68591576 68591706 131 + 1.350 1.255 -0.332
ENSG00000110075 E054 20.1463300 0.0006824726 0.5863977730 0.816604836 11 68596097 68596218 122 + 1.341 1.308 -0.116
ENSG00000110075 E055 21.3723612 0.0008015268 0.6243669003 0.838410181 11 68600341 68600494 154 + 1.364 1.335 -0.101
ENSG00000110075 E056 9.0130113 0.0015458092 0.3310012653 0.623288256 11 68601863 68601885 23 + 1.041 0.953 -0.325
ENSG00000110075 E057 12.9435980 0.0011639183 0.6400241983 0.847011537 11 68601886 68601969 84 + 1.161 1.126 -0.126
ENSG00000110075 E058 21.1905350 0.0007213282 0.5714787143 0.807665557 11 68603342 68603492 151 + 1.327 1.365 0.130
ENSG00000110075 E059 0.9988703 0.0115833161 0.1173981612 0.361959208 11 68609473 68609610 138 + 0.166 0.406 1.732
ENSG00000110075 E060 0.6261159 0.0148618690 0.1422077417 0.401204809 11 68609611 68609628 18 + 0.091 0.308 2.147
ENSG00000110075 E061 2.2656408 0.0079086642 0.0002497795 0.005021098 11 68609775 68609903 129 + 0.166 0.709 3.147
ENSG00000110075 E062 13.8067019 0.0010980324 0.8875245742 0.962397973 11 68609904 68609950 47 + 1.175 1.166 -0.032
ENSG00000110075 E063 8.4856072 0.0390253674 0.0968050310 0.324010583 11 68609951 68610023 73 + 1.059 0.872 -0.701
ENSG00000110075 E064 0.0000000       11 68613036 68613065 30 +      
ENSG00000110075 E065 183.4097346 0.0001360992 0.0088677222 0.074196669 11 68613066 68614631 1566 + 2.239 2.292 0.176
ENSG00000110075 E066 73.7108304 0.0020149056 0.0017789122 0.023338324 11 68614632 68615334 703 + 1.811 1.929 0.397

Help

Please Click HERE to learn more details about the results from DEXseq.