ENSG00000110079

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337908 ENSG00000110079 No_inf pgKDN_inf MS4A4A protein_coding protein_coding 9.819478 7.109142 10.75583 0.5584794 0.4186273 0.5966842 6.8452422 4.8718960 6.863453 1.2337322 1.4827750 0.4935936 0.6977333 0.704575 0.632725 -0.071850 0.8493493 0.0134598 FALSE TRUE
ENST00000343968 ENSG00000110079 No_inf pgKDN_inf MS4A4A protein_coding nonsense_mediated_decay 9.819478 7.109142 10.75583 0.5584794 0.4186273 0.5966842 1.4232209 0.5282953 1.809509 0.5282953 1.1440649 1.7570793 0.1352750 0.066225 0.170975 0.104750 0.8347279 0.0134598 FALSE TRUE
ENST00000532114 ENSG00000110079 No_inf pgKDN_inf MS4A4A protein_coding protein_coding 9.819478 7.109142 10.75583 0.5584794 0.4186273 0.5966842 0.7036583 0.0000000 1.522831 0.0000000 0.3949238 7.2600547 0.0648500 0.000000 0.142750 0.142750 0.0134598 0.0134598 FALSE TRUE
ENST00000679988 ENSG00000110079 No_inf pgKDN_inf MS4A4A protein_coding protein_coding 9.819478 7.109142 10.75583 0.5584794 0.4186273 0.5966842 0.2558744 0.7676233 0.000000 0.7676233 0.0000000 -6.2809995 0.0320750 0.096225 0.000000 -0.096225 0.8290051 0.0134598 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110079 E001 0.0000000       11 60185657 60185674 18 +      
ENSG00000110079 E002 0.0000000       11 60185675 60185701 27 +      
ENSG00000110079 E003 0.0000000       11 60185702 60185706 5 +      
ENSG00000110079 E004 0.0000000       11 60185707 60185815 109 +      
ENSG00000110079 E005 0.0000000       11 60185816 60185919 104 +      
ENSG00000110079 E006 0.0000000       11 60185920 60185925 6 +      
ENSG00000110079 E007 0.0000000       11 60185926 60185990 65 +      
ENSG00000110079 E008 0.0000000       11 60185991 60186039 49 +      
ENSG00000110079 E009 0.0000000       11 60186040 60186171 132 +      
ENSG00000110079 E010 0.0000000       11 60229458 60229616 159 +      
ENSG00000110079 E011 0.1272623 0.0130268688 4.044918e-01   11 60240066 60240153 88 + 0.000 0.107 8.651
ENSG00000110079 E012 0.0000000       11 60280541 60280559 19 +      
ENSG00000110079 E013 0.0000000       11 60280560 60280576 17 +      
ENSG00000110079 E014 0.2451451 0.0165293107 8.310572e-01   11 60280577 60280655 79 + 0.084 0.107 0.391
ENSG00000110079 E015 0.3627758 0.0170008679 7.703630e-01   11 60280656 60280665 10 + 0.155 0.107 -0.609
ENSG00000110079 E016 0.3627758 0.0170008679 7.703630e-01   11 60280666 60280668 3 + 0.155 0.107 -0.609
ENSG00000110079 E017 2.1662519 0.0068037267 1.781749e-01 0.4529442642 11 60280669 60280716 48 + 0.577 0.380 -0.988
ENSG00000110079 E018 1.4387126 0.2113023628 2.642660e-01 0.5572773074 11 60282594 60282739 146 + 0.466 0.265 -1.194
ENSG00000110079 E019 0.0000000       11 60290049 60290242 194 +      
ENSG00000110079 E020 9.0539867 0.0016961744 2.077751e-02 0.1298961354 11 60292225 60292384 160 + 1.083 0.872 -0.786
ENSG00000110079 E021 0.4985363 0.0155977228 2.042299e-01   11 60296871 60297022 152 + 0.084 0.265 1.976
ENSG00000110079 E022 8.7241703 0.0449597668 3.517444e-01 0.6419422590 11 60297197 60297325 129 + 1.035 0.918 -0.432
ENSG00000110079 E023 6.7603482 0.0059717492 9.069455e-02 0.3127770063 11 60301001 60301057 57 + 0.960 0.781 -0.687
ENSG00000110079 E024 11.2309054 0.0014451463 6.173096e-01 0.8342682630 11 60302559 60302717 159 + 1.068 1.106 0.139
ENSG00000110079 E025 5.1145366 0.0031081284 1.833852e-05 0.0005733248 11 60302718 60306099 3382 + 0.497 0.986 2.023
ENSG00000110079 E026 13.3613500 0.0012889103 6.659651e-02 0.2599562804 11 60306100 60306201 102 + 1.091 1.223 0.470
ENSG00000110079 E027 28.0286454 0.0007415763 9.636586e-01 0.9923478745 11 60308107 60308972 866 + 1.462 1.459 -0.013
ENSG00000110079 E028 0.0000000       11 60317865 60318080 216 +      

Help

Please Click HERE to learn more details about the results from DEXseq.