ENSG00000110092

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000227507 ENSG00000110092 No_inf pgKDN_inf CCND1 protein_coding protein_coding 152.0814 54.68829 214.355 1.422185 3.3539 1.970502 100.91478 26.67471 147.10061 2.541509 3.142646 2.462816 0.6212417 0.487075 0.687400 0.200325 0.008324285 0.008324285 FALSE TRUE
ENST00000542367 ENSG00000110092 No_inf pgKDN_inf CCND1 protein_coding retained_intron 152.0814 54.68829 214.355 1.422185 3.3539 1.970502 42.37861 23.22938 58.27695 1.829645 3.920750 1.326601 0.3135917 0.425800 0.271275 -0.154525 0.048256691 0.008324285 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110092 E001 2.8479703 0.0050164494 0.096805476 0.32401058 11 69641156 69641164 9 + 0.576 0.291 -1.535
ENSG00000110092 E002 14.0415108 0.0009457948 0.723662332 0.88903192 11 69641165 69641205 41 + 1.095 1.127 0.117
ENSG00000110092 E003 20.2420546 0.0006721042 0.664838560 0.86067407 11 69641206 69641230 25 + 1.257 1.224 -0.118
ENSG00000110092 E004 116.2963909 0.0001683661 0.001766245 0.02319471 11 69641231 69641511 281 + 2.011 1.901 -0.367
ENSG00000110092 E005 121.3454986 0.0001589043 0.013543219 0.09791420 11 69643031 69643246 216 + 2.024 1.941 -0.279
ENSG00000110092 E006 2.0677559 0.1024079153 0.099163741 0.32884267 11 69643247 69643317 71 + 0.353 0.637 1.411
ENSG00000110092 E007 3.1585836 0.0709842974 0.079587949 0.28942731 11 69643712 69643831 120 + 0.479 0.761 1.247
ENSG00000110092 E008 94.6892498 0.0001687338 0.278548062 0.57174893 11 69643832 69643991 160 + 1.909 1.869 -0.135
ENSG00000110092 E009 1.3347101 0.0095284374 0.242577192 0.53217289 11 69643992 69644188 197 + 0.274 0.464 1.117
ENSG00000110092 E010 0.6077974 0.0158095012 0.331641890 0.62381940 11 69647957 69647993 37 + 0.139 0.291 1.340
ENSG00000110092 E011 82.7129512 0.0009866913 0.998092588 1.00000000 11 69647994 69648142 149 + 1.843 1.843 0.002
ENSG00000110092 E012 1.9494947 0.0071526034 0.042078564 0.19960117 11 69648143 69648240 98 + 0.328 0.637 1.562
ENSG00000110092 E013 1710.9118992 0.0000405695 0.001662337 0.02212844 11 69651118 69654474 3357 + 3.149 3.163 0.045

Help

Please Click HERE to learn more details about the results from DEXseq.