ENSG00000110446

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000227880 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding protein_coding 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 8.385302 0.000000 5.166815 0.0000000 5.166815 9.0159210 0.06689167 0.000000 0.050725 0.050725 0.9486615 0.0069689 FALSE TRUE
ENST00000536491 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding protein_coding 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 14.674547 2.200380 29.272589 2.2003796 5.161597 3.7276771 0.14165000 0.045025 0.281450 0.236425 0.0069689 0.0069689 FALSE TRUE
ENST00000536784 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding nonsense_mediated_decay 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 24.725424 14.933216 20.167251 1.3933515 8.253744 0.4332389 0.26564167 0.303200 0.197150 -0.106050 0.7857737 0.0069689 FALSE TRUE
ENST00000537307 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding protein_coding 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 1.049003 3.147008 0.000000 3.1470079 0.000000 -8.3024141 0.01752500 0.052575 0.000000 -0.052575 0.7999352 0.0069689 FALSE TRUE
ENST00000538739 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding protein_coding 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 28.642546 17.318711 27.043997 2.0758637 3.127743 0.6426774 0.31199167 0.358325 0.259025 -0.099300 0.6241919 0.0069689 FALSE TRUE
ENST00000541505 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding nonsense_mediated_decay 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 8.849326 6.128468 14.187132 0.4382663 4.776256 1.2096490 0.10451667 0.127050 0.136125 0.009075 0.9602787 0.0069689 TRUE TRUE
ENST00000544101 ENSG00000110446 No_inf pgKDN_inf SLC15A3 protein_coding retained_intron 94.76806 49.42455 104.0407 3.675296 3.691224 1.073695 6.388898 3.328229 6.027112 1.4216139 3.794750 0.8547755 0.06454167 0.064825 0.055250 -0.009575 0.8347279 0.0069689   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110446 E001 0.0000000       11 60937060 60937083 24 -      
ENSG00000110446 E002 0.0000000       11 60937084 60937087 4 -      
ENSG00000110446 E003 0.0000000       11 60937088 60937090 3 -      
ENSG00000110446 E004 0.1176306 0.0117217181 1.0000000000   11 60937091 60937160 70 - 0.071 0.000 -9.067
ENSG00000110446 E005 87.8592605 0.0001817173 0.6162859339 0.833636777 11 60937161 60937373 213 - 1.925 1.944 0.063
ENSG00000110446 E006 0.6256450 0.2242544574 0.0778208030 0.285445583 11 60937516 60937566 51 - 0.071 0.370 2.920
ENSG00000110446 E007 56.9595315 0.0002964853 0.2903255893 0.583986138 11 60937870 60937925 56 - 1.761 1.720 -0.137
ENSG00000110446 E008 65.6218788 0.0002589245 0.2031363229 0.485708549 11 60937926 60938025 100 - 1.823 1.777 -0.154
ENSG00000110446 E009 1.0991679 0.1642571251 0.5515642658 0.795424132 11 60938026 60938132 107 - 0.277 0.370 0.596
ENSG00000110446 E010 1.3787743 0.0888370947 0.0042943661 0.044626656 11 60939212 60939479 268 - 0.132 0.605 3.089
ENSG00000110446 E011 83.2454900 0.0007967668 0.6622071574 0.859164802 11 60939480 60939638 159 - 1.902 1.920 0.058
ENSG00000110446 E012 8.7367731 0.0021888673 0.0002485606 0.005000324 11 60939639 60941121 1483 - 0.814 1.160 1.286
ENSG00000110446 E013 52.2806446 0.0003023068 0.1090454252 0.346690401 11 60941122 60941290 169 - 1.733 1.667 -0.224
ENSG00000110446 E014 4.5691948 0.0256052718 0.0056825604 0.054273635 11 60941291 60942034 744 - 0.565 0.924 1.471
ENSG00000110446 E015 63.0005312 0.0003168164 0.3945188539 0.679341860 11 60942035 60942139 105 - 1.800 1.770 -0.102
ENSG00000110446 E016 30.1383782 0.0006495509 0.8417961527 0.943210595 11 60942140 60942145 6 - 1.480 1.471 -0.030
ENSG00000110446 E017 0.8605354 0.2025931619 0.3179769574 0.610725018 11 60942146 60943505 1360 - 0.186 0.370 1.334
ENSG00000110446 E018 0.0000000       11 60943506 60943688 183 -      
ENSG00000110446 E019 79.0687024 0.0002294286 0.8745763302 0.957112996 11 60943689 60943836 148 - 1.888 1.885 -0.009
ENSG00000110446 E020 109.3452148 0.0044081097 0.4708964597 0.738466203 11 60946532 60946821 290 - 2.015 2.044 0.097
ENSG00000110446 E021 0.1187032 0.0118056783 1.0000000000   11 60947775 60947844 70 - 0.071 0.000 -9.067
ENSG00000110446 E022 90.1565461 0.0002103077 0.6534018013 0.854337626 11 60950994 60951366 373 - 1.937 1.953 0.056
ENSG00000110446 E023 46.4984946 0.0003513197 0.1627217921 0.431298367 11 60951367 60952176 810 - 1.681 1.620 -0.207
ENSG00000110446 E024 0.2541163 0.0160361587 0.0908583807   11 60952501 60952653 153 - 0.000 0.224 11.798

Help

Please Click HERE to learn more details about the results from DEXseq.