ENSG00000110619

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000278224 ENSG00000110619 No_inf pgKDN_inf CARS1 protein_coding protein_coding 20.31045 17.66228 21.58476 0.6737489 0.7787624 0.2891933 3.684841 4.112274 2.6129717 0.8696984 0.4517927 -0.6522382 0.18339167 0.233125 0.122825 -0.110300 0.608938977 0.008951044 FALSE TRUE
ENST00000397111 ENSG00000110619 No_inf pgKDN_inf CARS1 protein_coding protein_coding 20.31045 17.66228 21.58476 0.6737489 0.7787624 0.2891933 9.961294 6.139507 13.4746929 0.6341732 0.4176651 1.1327799 0.48375833 0.345275 0.624900 0.279625 0.008951044 0.008951044 FALSE TRUE
ENST00000484484 ENSG00000110619 No_inf pgKDN_inf CARS1 protein_coding retained_intron 20.31045 17.66228 21.58476 0.6737489 0.7787624 0.2891933 2.631731 3.327140 2.3457599 0.1412463 0.3574003 -0.5024196 0.13323333 0.188900 0.107800 -0.081100 0.538519942 0.008951044 TRUE TRUE
MSTRG.4271.10 ENSG00000110619 No_inf pgKDN_inf CARS1 protein_coding   20.31045 17.66228 21.58476 0.6737489 0.7787624 0.2891933 1.494662 1.804192 0.9898611 0.9180646 0.6015568 -0.8595275 0.07339167 0.101600 0.043050 -0.058550 0.776497192 0.008951044 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110619 E001 0.0000000       11 3000922 3000928 7 -      
ENSG00000110619 E002 0.1186381 0.0118149095 0.576186659   11 3000929 3000929 1 - 0.092 0.000 -12.042
ENSG00000110619 E003 32.4159027 0.0004505536 0.793294609 0.92116932 11 3000930 3001248 319 - 1.518 1.530 0.044
ENSG00000110619 E004 1.9967645 0.1100174654 0.071997819 0.27208032 11 3001829 3001961 133 - 0.289 0.606 1.684
ENSG00000110619 E005 2.9444028 0.0048869985 0.568048689 0.80568829 11 3001962 3001969 8 - 0.557 0.633 0.339
ENSG00000110619 E006 27.1176080 0.0005229959 0.659612330 0.85796531 11 3001970 3002053 84 - 1.461 1.437 -0.084
ENSG00000110619 E007 6.4013062 0.0023282989 0.176148492 0.45029429 11 3002054 3002174 121 - 0.793 0.934 0.546
ENSG00000110619 E008 10.4945577 0.0013717944 0.017007174 0.11383648 11 3002175 3002540 366 - 0.945 1.151 0.754
ENSG00000110619 E009 21.6771077 0.0017415642 0.707030825 0.88116926 11 3002541 3002600 60 - 1.344 1.367 0.082
ENSG00000110619 E010 14.2837096 0.0009726462 0.642058296 0.84818695 11 3005366 3005433 68 - 1.202 1.167 -0.124
ENSG00000110619 E011 17.3246276 0.0008932327 0.129319481 0.38147495 11 3006879 3006959 81 - 1.208 1.312 0.365
ENSG00000110619 E012 2.1202810 0.0066987490 0.018614928 0.12097572 11 3006960 3007619 660 - 0.289 0.633 1.799
ENSG00000110619 E013 3.1127682 0.0565194130 0.039361153 0.19218762 11 3007620 3009533 1914 - 0.424 0.745 1.460
ENSG00000110619 E014 17.0909814 0.0008428646 0.090147427 0.31190732 11 3012195 3012276 82 - 1.195 1.312 0.411
ENSG00000110619 E015 16.3285545 0.0011029177 0.174128151 0.44772253 11 3015781 3015849 69 - 1.188 1.284 0.337
ENSG00000110619 E016 27.2850335 0.0058841063 0.961817282 0.99168477 11 3017106 3017295 190 - 1.450 1.453 0.008
ENSG00000110619 E017 0.5077596 0.0150629068 0.038199757 0.18868630 11 3017296 3017856 561 - 0.000 0.304 14.133
ENSG00000110619 E018 14.8101761 0.0009616242 0.915190261 0.97341389 11 3017857 3017954 98 - 1.195 1.203 0.027
ENSG00000110619 E019 0.2533610 0.0159923794 0.219737653   11 3017955 3018407 453 - 0.000 0.178 13.133
ENSG00000110619 E020 12.6515557 0.0506198418 0.458621893 0.73045688 11 3018408 3018511 104 - 1.084 1.181 0.350
ENSG00000110619 E021 0.1272623 0.0123465627 0.502382412   11 3018512 3018540 29 - 0.000 0.098 12.133
ENSG00000110619 E022 18.4367038 0.0011933595 0.756726798 0.90422951 11 3018620 3018749 130 - 1.299 1.278 -0.074
ENSG00000110619 E023 12.2074889 0.0011126769 0.646511701 0.85038715 11 3019139 3019189 51 - 1.139 1.102 -0.133
ENSG00000110619 E024 14.8609839 0.0009016530 0.206081900 0.48968284 11 3019190 3019267 78 - 1.245 1.151 -0.331
ENSG00000110619 E025 13.8069502 0.0010441600 0.004231974 0.04416550 11 3020220 3020332 113 - 1.267 1.046 -0.789
ENSG00000110619 E026 10.5457419 0.0314198487 0.062119176 0.25034700 11 3026676 3026797 122 - 1.154 0.947 -0.755
ENSG00000110619 E027 3.8513924 0.0134784434 0.013890200 0.09948925 11 3026798 3028712 1915 - 0.495 0.818 1.388
ENSG00000110619 E028 0.4990093 0.0183620386 0.287911781   11 3028713 3028995 283 - 0.092 0.245 1.683
ENSG00000110619 E029 5.1802409 0.0295987054 0.037179372 0.18562968 11 3028996 3029083 88 - 0.908 0.633 -1.108
ENSG00000110619 E030 4.2108626 0.0808008129 0.081446485 0.29339666 11 3029084 3029084 1 - 0.839 0.548 -1.223
ENSG00000110619 E031 0.0000000       11 3029085 3029302 218 -      
ENSG00000110619 E032 4.8195388 0.0402123064 0.048137001 0.21593787 11 3029303 3029443 141 - 0.882 0.606 -1.124
ENSG00000110619 E033 5.4274908 0.0026511238 0.153071244 0.41737839 11 3038050 3038130 81 - 0.721 0.880 0.629
ENSG00000110619 E034 8.8185033 0.0021641846 0.772049202 0.91225110 11 3038131 3038199 69 - 0.978 1.005 0.098
ENSG00000110619 E035 5.8054658 0.0273925494 0.062942538 0.25234095 11 3039194 3039214 21 - 0.933 0.703 -0.902
ENSG00000110619 E036 8.7509701 0.0023368028 0.111498673 0.35062500 11 3039215 3039292 78 - 1.057 0.908 -0.554
ENSG00000110619 E037 5.8574043 0.0642935923 0.705065779 0.88015663 11 3039835 3039931 97 - 0.869 0.801 -0.265
ENSG00000110619 E038 0.1186381 0.0118149095 0.576186659   11 3039932 3040088 157 - 0.092 0.000 -12.042
ENSG00000110619 E039 0.0000000       11 3040448 3040523 76 -      
ENSG00000110619 E040 0.0000000       11 3040524 3040581 58 -      
ENSG00000110619 E041 0.0000000       11 3040896 3040984 89 -      
ENSG00000110619 E042 0.0000000       11 3040985 3041031 47 -      
ENSG00000110619 E043 4.4945740 0.0197780180 0.231494485 0.52011762 11 3042165 3042256 92 - 0.809 0.658 -0.618
ENSG00000110619 E044 0.0000000       11 3042257 3042330 74 -      
ENSG00000110619 E045 2.0696797 0.0092033381 0.563169677 0.80267150 11 3047753 3048001 249 - 0.527 0.443 -0.416
ENSG00000110619 E046 0.2533610 0.0159923794 0.219737653   11 3054877 3055039 163 - 0.000 0.178 13.133
ENSG00000110619 E047 3.8974433 0.0714964324 0.435160807 0.71209572 11 3057343 3057613 271 - 0.740 0.633 -0.449

Help

Please Click HERE to learn more details about the results from DEXseq.