ENSG00000110628

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000347936 ENSG00000110628 No_inf pgKDN_inf SLC22A18 protein_coding protein_coding 58.27763 58.80504 52.65702 3.285522 0.7513449 -0.1592853 27.358251 19.837131 25.454389 3.46769830 0.8628033 0.3595506 0.46900833 0.341750 0.484000 0.14225 4.292547e-01 7.052963e-09 FALSE TRUE
ENST00000498244 ENSG00000110628 No_inf pgKDN_inf SLC22A18 protein_coding retained_intron 58.27763 58.80504 52.65702 3.285522 0.7513449 -0.1592853 2.908299 6.997835 0.000000 1.44032574 0.0000000 -9.4528249 0.04764167 0.116300 0.000000 -0.11630 7.052963e-09 7.052963e-09   FALSE
ENST00000649076 ENSG00000110628 No_inf pgKDN_inf SLC22A18 protein_coding protein_coding 58.27763 58.80504 52.65702 3.285522 0.7513449 -0.1592853 11.801243 11.436752 14.221879 4.22981380 3.3607594 0.3141879 0.20803333 0.199050 0.269950 0.07090 8.420541e-01 7.052963e-09 FALSE TRUE
MSTRG.4270.10 ENSG00000110628 No_inf pgKDN_inf SLC22A18 protein_coding   58.27763 58.80504 52.65702 3.285522 0.7513449 -0.1592853 3.133665 5.507539 1.118614 0.05813922 0.1556625 -2.2894734 0.05321667 0.094425 0.021325 -0.07310 1.116430e-02 7.052963e-09 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110628 E001 1.2048035 0.0108772903 1.194855e-01 3.653882e-01 11 2899721 2899806 86 + 0.459 0.223 -1.488
ENSG00000110628 E002 0.3727544 0.0165690102 7.073887e-01   11 2902240 2902277 38 + 0.103 0.160 0.734
ENSG00000110628 E003 0.3727544 0.0165690102 7.073887e-01   11 2902278 2902282 5 + 0.103 0.160 0.734
ENSG00000110628 E004 5.3077832 0.0027131226 4.495338e-01 7.231783e-01 11 2902283 2902364 82 + 0.745 0.833 0.347
ENSG00000110628 E005 0.1186381 0.0118718587 4.448653e-01   11 2902420 2902718 299 + 0.103 0.000 -10.069
ENSG00000110628 E006 0.4736100 0.0162963986 2.854358e-02   11 2902745 2902822 78 + 0.317 0.000 -12.069
ENSG00000110628 E007 0.6154143 0.0200026714 8.124411e-01 9.309947e-01 11 2903114 2903213 100 + 0.187 0.223 0.319
ENSG00000110628 E008 19.7074104 0.0007243875 1.508987e-01 4.137765e-01 11 2903214 2903298 85 + 1.362 1.270 -0.320
ENSG00000110628 E009 23.3200066 0.0028110871 6.809600e-01 8.681671e-01 11 2903299 2903375 77 + 1.396 1.372 -0.084
ENSG00000110628 E010 12.0293318 0.0268382364 9.403124e-01 9.830357e-01 11 2903376 2903489 114 + 1.116 1.108 -0.030
ENSG00000110628 E011 18.9919546 0.0007425519 2.728807e-01 5.666480e-01 11 2908233 2908330 98 + 1.336 1.265 -0.247
ENSG00000110628 E012 30.8388081 0.0005136367 1.006652e-01 3.312130e-01 11 2909196 2909272 77 + 1.545 1.461 -0.289
ENSG00000110628 E013 33.7338920 0.0052719823 5.484338e-02 2.332563e-01 11 2909273 2909356 84 + 1.595 1.487 -0.370
ENSG00000110628 E014 34.7625546 0.0005969150 3.266590e-04 6.235732e-03 11 2909578 2909710 133 + 1.640 1.464 -0.602
ENSG00000110628 E015 1.3883388 0.0091121675 9.215973e-03 7.621194e-02 11 2909711 2909818 108 + 0.103 0.509 3.056
ENSG00000110628 E016 19.1923580 0.0007335400 2.361362e-14 3.824556e-12 11 2914236 2915166 931 + 0.887 1.471 2.090
ENSG00000110628 E017 16.9641574 0.0008136162 3.628526e-14 5.688981e-12 11 2915167 2916145 979 + 0.804 1.426 2.258
ENSG00000110628 E018 2.7313232 0.0053332033 2.021563e-01 4.846130e-01 11 2916146 2916208 63 + 0.459 0.638 0.833
ENSG00000110628 E019 2.8682172 0.0050128819 6.009322e-02 2.459453e-01 11 2916209 2916235 27 + 0.417 0.681 1.236
ENSG00000110628 E020 6.4061984 0.0029842662 8.619833e-06 3.010979e-04 11 2916236 2916414 179 + 0.498 1.025 2.160
ENSG00000110628 E021 4.7749810 0.0049863168 1.432906e-04 3.188215e-03 11 2916415 2916621 207 + 0.417 0.911 2.149
ENSG00000110628 E022 18.1353669 0.0129020865 3.326164e-01 6.247590e-01 11 2916622 2916642 21 + 1.319 1.244 -0.266
ENSG00000110628 E023 21.2695847 0.0007334015 9.552438e-01 9.891523e-01 11 2916643 2916681 39 + 1.341 1.346 0.018
ENSG00000110628 E024 29.1712865 0.0004924546 3.446537e-01 6.358228e-01 11 2916682 2916740 59 + 1.503 1.454 -0.169
ENSG00000110628 E025 0.0000000       11 2916948 2917023 76 +      
ENSG00000110628 E026 46.6488465 0.0055440571 1.568959e-01 4.232640e-01 11 2917988 2918095 108 + 1.714 1.642 -0.243
ENSG00000110628 E027 1.9699508 0.0073734521 9.016636e-01 9.683843e-01 11 2918906 2919008 103 + 0.459 0.478 0.097
ENSG00000110628 E028 39.0909881 0.0003473319 4.112800e-03 4.330726e-02 11 2919307 2919407 101 + 1.669 1.538 -0.447
ENSG00000110628 E029 16.2330293 0.0072667908 3.053607e-06 1.223576e-04 11 2919408 2921238 1831 + 0.969 1.364 1.409
ENSG00000110628 E030 9.4313288 0.0014760870 3.184531e-09 2.496431e-07 11 2921352 2921967 616 + 0.566 1.191 2.434
ENSG00000110628 E031 4.3531282 0.0033432277 4.435097e-02 2.058719e-01 11 2921968 2922101 134 + 0.566 0.818 1.056
ENSG00000110628 E032 42.0740614 0.0021539355 2.665863e-01 5.600788e-01 11 2922102 2922203 102 + 1.659 1.608 -0.174
ENSG00000110628 E033 52.2615516 0.0003622178 2.689142e-01 5.625483e-01 11 2922436 2922556 121 + 1.746 1.704 -0.144
ENSG00000110628 E034 45.7473744 0.0010120079 1.951748e-02 1.250546e-01 11 2925010 2925246 237 + 1.720 1.619 -0.343

Help

Please Click HERE to learn more details about the results from DEXseq.