ENSG00000110651

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263645 ENSG00000110651 No_inf pgKDN_inf CD81 protein_coding protein_coding 859.7946 664.5394 945.7444 5.977381 7.402991 0.5090892 708.5078 474.5030 810.4848 6.404554 5.403253 0.7723553 0.8132917 0.714300 0.85725 0.142950 2.067527e-11 2.067527e-11 FALSE TRUE
ENST00000527343 ENSG00000110651 No_inf pgKDN_inf CD81 protein_coding protein_coding 859.7946 664.5394 945.7444 5.977381 7.402991 0.5090892 130.8209 172.6018 119.2274 7.948357 13.995683 -0.5336933 0.1627083 0.259525 0.12575 -0.133775 1.476181e-06 2.067527e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110651 E001 0.0000000       11 2376177 2376201 25 +      
ENSG00000110651 E002 0.2545247 2.513770e-01 2.178099e-01   11 2376202 2376357 156 + 0.000 0.191 11.150
ENSG00000110651 E003 0.1272623 1.227974e-02 4.203797e-01   11 2376821 2376920 100 + 0.000 0.106 11.806
ENSG00000110651 E004 338.1569804 6.056127e-05 6.173561e-04 1.025138e-02 11 2377310 2377615 306 + 2.554 2.497 -0.188
ENSG00000110651 E005 1.8083242 3.266675e-02 1.901764e-01 4.692317e-01 11 2378931 2379206 276 + 0.529 0.324 -1.106
ENSG00000110651 E006 0.8601509 1.404143e-02 4.887269e-01 7.519325e-01 11 2382460 2382550 91 + 0.217 0.324 0.769
ENSG00000110651 E007 0.1265070 1.225478e-02 4.204306e-01   11 2384650 2384662 13 + 0.000 0.106 11.806
ENSG00000110651 E008 0.1265070 1.225478e-02 4.204306e-01   11 2384663 2384682 20 + 0.000 0.106 11.806
ENSG00000110651 E009 0.2543986 1.590442e-02 1.697043e-01   11 2385666 2385806 141 + 0.000 0.191 12.716
ENSG00000110651 E010 0.2447669 1.592620e-02 8.499100e-01   11 2386057 2386085 29 + 0.085 0.106 0.354
ENSG00000110651 E011 0.4991656 2.165692e-02 2.175204e-01   11 2386086 2386156 71 + 0.085 0.262 1.939
ENSG00000110651 E012 1.9948438 6.971515e-03 1.273319e-02 9.393405e-02 11 2386157 2386554 398 + 0.271 0.635 1.938
ENSG00000110651 E013 0.8705354 1.241797e-02 1.455422e-01 4.061041e-01 11 2386555 2386639 85 + 0.156 0.377 1.675
ENSG00000110651 E014 0.2541163 1.589879e-02 1.697072e-01   11 2390095 2390102 8 + 0.000 0.191 12.717
ENSG00000110651 E015 0.7540721 1.411232e-02 4.948783e-02 2.193882e-01 11 2390103 2390183 81 + 0.085 0.377 2.675
ENSG00000110651 E016 241.7927511 7.745752e-05 2.579541e-01 5.501620e-01 11 2390412 2390445 34 + 2.393 2.372 -0.073
ENSG00000110651 E017 592.5741114 4.443073e-05 2.483277e-02 1.448708e-01 11 2390446 2390526 81 + 2.784 2.757 -0.091
ENSG00000110651 E018 2.4945809 5.903612e-03 5.379893e-03 5.224328e-02 11 2391075 2391382 308 + 0.319 0.712 1.938
ENSG00000110651 E019 2.8670873 1.073024e-02 4.624903e-03 4.682552e-02 11 2391383 2391482 100 + 0.362 0.756 1.856
ENSG00000110651 E020 36.6865143 3.830489e-04 2.732526e-21 8.279553e-19 11 2391483 2393847 2365 + 1.283 1.774 1.682
ENSG00000110651 E021 9.1774965 4.926264e-03 8.631970e-05 2.106496e-03 11 2393848 2394094 247 + 0.792 1.171 1.412
ENSG00000110651 E022 797.4705404 4.460774e-05 2.383321e-02 1.412860e-01 11 2394095 2394192 98 + 2.911 2.888 -0.079
ENSG00000110651 E023 2.7036983 2.131252e-02 3.443112e-01 6.356135e-01 11 2394850 2394971 122 + 0.500 0.635 0.616
ENSG00000110651 E024 799.3021472 3.557581e-05 1.266880e-01 3.772994e-01 11 2394972 2395046 75 + 2.909 2.893 -0.052
ENSG00000110651 E025 2.3393421 1.555147e-02 2.392868e-01 5.282076e-01 11 2395047 2395415 369 + 0.437 0.607 0.813
ENSG00000110651 E026 1044.6774946 4.212511e-05 2.933981e-01 5.869922e-01 11 2395416 2395520 105 + 3.022 3.013 -0.030
ENSG00000110651 E027 4.4191551 5.701478e-03 2.994441e-01 5.923424e-01 11 2395521 2395868 348 + 0.670 0.796 0.514
ENSG00000110651 E028 1122.5884927 4.224438e-05 7.909265e-01 9.199048e-01 11 2395869 2395970 102 + 3.048 3.051 0.010
ENSG00000110651 E029 3.7178867 4.489162e-03 1.369965e-02 9.862316e-02 11 2395971 2396312 342 + 0.500 0.815 1.353
ENSG00000110651 E030 4.8561953 2.948427e-03 5.160711e-04 8.967068e-03 11 2396313 2396627 315 + 0.529 0.942 1.701
ENSG00000110651 E031 1022.3727853 5.654707e-05 4.389068e-02 2.046335e-01 11 2396628 2396714 87 + 2.999 3.019 0.065
ENSG00000110651 E032 3.0296100 4.637536e-03 4.262944e-01 7.049478e-01 11 2396715 2396803 89 + 0.650 0.543 -0.477
ENSG00000110651 E033 3114.2431030 3.208920e-05 4.868252e-02 2.174498e-01 11 2396804 2397802 999 + 3.487 3.497 0.033

Help

Please Click HERE to learn more details about the results from DEXseq.