ENSG00000110721

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265689 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding protein_coding 20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 9.2748673 9.866303 8.39187125 0.3051988 0.53166662 -0.2332604 0.49758333 0.316425 0.638750 0.322325 0.005410975 0.005410975 FALSE TRUE
ENST00000525155 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding nonsense_mediated_decay 20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 0.6737143 1.933164 0.08797854 1.0470090 0.08797854 -4.3097982 0.02341667 0.063525 0.006725 -0.056800 0.373615565 0.005410975 TRUE TRUE
ENST00000533728 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding protein_coding_CDS_not_defined 20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 2.3246448 4.874812 0.49915414 2.0265218 0.29553483 -3.2621287 0.09340833 0.152375 0.038225 -0.114150 0.676818807 0.005410975   FALSE
MSTRG.5066.10 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding   20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 1.2648543 2.675592 0.37694690 0.6027318 0.37694690 -2.7950327 0.05147500 0.085925 0.027150 -0.058775 0.363118561 0.005410975 FALSE FALSE
MSTRG.5066.13 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding   20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 1.7155896 3.323238 0.80064171 0.6387058 0.33919681 -2.0397882 0.07568333 0.105450 0.062150 -0.043300 0.780026304 0.005410975   FALSE
MSTRG.5066.4 ENSG00000110721 No_inf pgKDN_inf CHKA protein_coding   20.70157 31.2672 13.16244 1.006472 0.2592837 -1.247589 4.1380763 7.566885 1.69871200 1.6668111 0.68026567 -2.1486956 0.18469167 0.241375 0.127350 -0.114025 0.668374638 0.005410975 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110721 E001 17.6131735 0.0009694594 2.417961e-02 1.424627e-01 11 68052859 68053511 653 - 1.341 1.184 -0.551
ENSG00000110721 E002 0.0000000       11 68053512 68053514 3 -      
ENSG00000110721 E003 1.7427450 0.0087223920 7.198475e-01 8.871008e-01 11 68053515 68053787 273 - 0.379 0.434 0.303
ENSG00000110721 E004 4.7099882 0.0293990976 8.886627e-01 9.627998e-01 11 68053788 68053819 32 - 0.743 0.724 -0.076
ENSG00000110721 E005 12.6601048 0.0011542257 7.061033e-01 8.806771e-01 11 68053820 68053920 101 - 1.085 1.115 0.110
ENSG00000110721 E006 7.7079300 0.0021082466 4.908555e-01 7.533379e-01 11 68053921 68053948 28 - 0.862 0.933 0.270
ENSG00000110721 E007 12.5227703 0.0193223378 9.274685e-01 9.784271e-01 11 68053949 68054047 99 - 1.097 1.103 0.024
ENSG00000110721 E008 0.9870998 0.1424324532 8.100522e-01 9.298971e-01 11 68061493 68061599 107 - 0.311 0.269 -0.281
ENSG00000110721 E009 3.1373120 0.0077666592 5.651722e-02 2.372229e-01 11 68061600 68061830 231 - 0.379 0.664 1.373
ENSG00000110721 E010 10.0209944 0.0089185422 6.281029e-01 8.401811e-01 11 68061953 68062034 82 - 1.046 0.997 -0.177
ENSG00000110721 E011 15.8953215 0.0008724548 5.185498e-01 7.735140e-01 11 68064525 68064631 107 - 1.164 1.212 0.171
ENSG00000110721 E012 20.0916076 0.0012713983 7.895288e-01 9.192308e-01 11 68065786 68065894 109 - 1.281 1.299 0.062
ENSG00000110721 E013 13.8750441 0.0018803886 9.927262e-01 1.000000e+00 11 68066429 68066471 43 - 1.143 1.143 0.000
ENSG00000110721 E014 11.4992522 0.0135221505 6.538380e-01 8.546573e-01 11 68066472 68066502 31 - 1.097 1.054 -0.157
ENSG00000110721 E015 7.9210277 0.0027563332 8.269354e-01 9.373403e-01 11 68066503 68066516 14 - 0.938 0.915 -0.086
ENSG00000110721 E016 0.1272623 0.0124404185 1.000000e+00   11 68068800 68068878 79 - 0.000 0.069 8.246
ENSG00000110721 E017 9.4790431 0.0513039275 2.113585e-01 4.962955e-01 11 68068879 68068937 59 - 1.085 0.941 -0.527
ENSG00000110721 E018 8.1008200 0.0118752797 5.106675e-02 2.237215e-01 11 68070189 68070222 34 - 1.059 0.857 -0.756
ENSG00000110721 E019 11.7477117 0.0012487508 5.749263e-01 8.096454e-01 11 68070223 68070293 71 - 1.109 1.060 -0.176
ENSG00000110721 E020 12.1211863 0.0013517572 4.433980e-01 7.182593e-01 11 68070724 68070815 92 - 1.132 1.067 -0.235
ENSG00000110721 E021 9.9818676 0.0238143944 1.466420e-01 4.076816e-01 11 68070816 68070857 42 - 1.109 0.958 -0.552
ENSG00000110721 E022 0.6257372 0.0149649534 5.391624e-01 7.876909e-01 11 68072710 68072825 116 - 0.130 0.227 0.981
ENSG00000110721 E023 14.3524307 0.0111013865 5.059627e-01 7.647417e-01 11 68074717 68074830 114 - 1.194 1.137 -0.202
ENSG00000110721 E024 6.1781636 0.0141797365 4.846960e-01 7.487639e-01 11 68081404 68081457 54 - 0.882 0.801 -0.313
ENSG00000110721 E025 3.9874848 0.0218775021 3.611508e-01 6.507473e-01 11 68081458 68081726 269 - 0.578 0.710 0.566
ENSG00000110721 E026 6.8952700 0.0020902640 1.326718e-02 9.653618e-02 11 68081727 68081848 122 - 0.652 0.941 1.151
ENSG00000110721 E027 18.8209152 0.0008181965 3.650385e-06 1.430584e-04 11 68081849 68082490 642 - 0.987 1.352 1.303
ENSG00000110721 E028 3.0285842 0.0047961572 4.066978e-03 4.292991e-02 11 68082491 68082520 30 - 0.230 0.680 2.440
ENSG00000110721 E029 16.3151654 0.0189996738 2.120569e-04 4.388749e-03 11 68082521 68083343 823 - 0.920 1.295 1.357
ENSG00000110721 E030 0.8726492 0.0412114798 8.003403e-01 9.252794e-01 11 68089821 68089880 60 - 0.230 0.269 0.303
ENSG00000110721 E031 0.2539903 0.0161247575 6.019025e-01   11 68089881 68089891 11 - 0.000 0.128 9.246
ENSG00000110721 E032 2.5164361 0.0067674183 8.049545e-06 2.834383e-04 11 68097019 68097130 112 - 0.840 0.227 -3.107
ENSG00000110721 E033 0.0000000       11 68120790 68120827 38 -      
ENSG00000110721 E034 6.5428547 0.0022515108 1.981083e-06 8.433129e-05 11 68120828 68121444 617 - 1.120 0.630 -1.901

Help

Please Click HERE to learn more details about the results from DEXseq.