ENSG00000110768

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265963 ENSG00000110768 No_inf pgKDN_inf GTF2H1 protein_coding protein_coding 24.53675 18.45469 28.87411 0.3204144 1.056781 0.645507 10.972646 9.2951104 14.341562 1.3443657 3.034329 0.6251126 0.4580250 0.503975 0.507850 0.003875 1.00000000 0.01715588 FALSE TRUE
ENST00000418116 ENSG00000110768 No_inf pgKDN_inf GTF2H1 protein_coding retained_intron 24.53675 18.45469 28.87411 0.3204144 1.056781 0.645507 3.355164 0.2032239 4.414045 0.2032239 1.364243 4.3749245 0.1212333 0.010900 0.148900 0.138000 0.01715588 0.01715588 FALSE TRUE
ENST00000526630 ENSG00000110768 No_inf pgKDN_inf GTF2H1 protein_coding protein_coding 24.53675 18.45469 28.87411 0.3204144 1.056781 0.645507 2.998086 3.5686757 2.922506 0.5582787 1.127236 -0.2872916 0.1309250 0.194125 0.101925 -0.092200 0.56271378 0.01715588 FALSE FALSE
MSTRG.4501.10 ENSG00000110768 No_inf pgKDN_inf GTF2H1 protein_coding   24.53675 18.45469 28.87411 0.3204144 1.056781 0.645507 1.526461 0.0000000 0.000000 0.0000000 0.000000 0.0000000 0.0569000 0.000000 0.000000 0.000000   0.01715588 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110768 E001 0.9532027 0.0120624772 0.091420312 0.31401497 11 18322295 18322546 252 + 0.379 0.114 -2.208
ENSG00000110768 E002 0.1176306 0.0118164356 0.820815007   11 18322547 18322556 10 + 0.079 0.000 -11.281
ENSG00000110768 E003 1.3057227 0.0094996942 0.022664836 0.13705632 11 18322557 18322566 10 + 0.475 0.114 -2.722
ENSG00000110768 E004 1.3057227 0.0094996942 0.022664836 0.13705632 11 18322567 18322567 1 + 0.475 0.114 -2.722
ENSG00000110768 E005 1.3057227 0.0094996942 0.022664836 0.13705632 11 18322568 18322568 1 + 0.475 0.114 -2.722
ENSG00000110768 E006 1.7970543 0.0074703421 0.102067365 0.33381246 11 18322569 18322581 13 + 0.530 0.280 -1.401
ENSG00000110768 E007 8.5757884 0.0154752673 0.242426259 0.53208879 11 18322582 18322740 159 + 1.023 0.899 -0.462
ENSG00000110768 E008 0.2356421 0.0157206042 0.417288778   11 18324236 18324296 61 + 0.145 0.000 -12.196
ENSG00000110768 E009 0.1187032 0.0118302783 0.820880697   11 18325947 18325969 23 + 0.079 0.000 -11.281
ENSG00000110768 E010 0.2373413 0.0157110029 0.417442406   11 18325970 18326019 50 + 0.145 0.000 -12.196
ENSG00000110768 E011 0.6167661 0.0143214990 0.369966974 0.65823708 11 18326020 18326153 134 + 0.145 0.280 1.184
ENSG00000110768 E012 0.2346346 0.0157273181 0.417134394   11 18332662 18333059 398 + 0.145 0.000 -12.196
ENSG00000110768 E013 5.6763251 0.0071771184 0.270553395 0.56423476 11 18333060 18333096 37 + 0.867 0.742 -0.494
ENSG00000110768 E014 13.4407834 0.0012932167 0.216980419 0.50323035 11 18333097 18333228 132 + 1.191 1.095 -0.342
ENSG00000110768 E015 0.7445018 0.0140987191 0.190243714 0.46929219 11 18333229 18333609 381 + 0.145 0.343 1.599
ENSG00000110768 E016 19.7368415 0.0007705569 0.139042262 0.39650533 11 18335754 18335946 193 + 1.348 1.252 -0.335
ENSG00000110768 E017 6.8910688 0.0242527172 0.377294185 0.66430480 11 18338109 18338139 31 + 0.932 0.828 -0.400
ENSG00000110768 E018 13.3725343 0.0010869137 0.008068022 0.06950019 11 18338140 18338216 77 + 1.228 1.015 -0.768
ENSG00000110768 E019 12.2725798 0.0061260469 0.003498928 0.03876444 11 18338217 18338274 58 + 1.207 0.946 -0.948
ENSG00000110768 E020 15.6809076 0.0009273655 0.006100058 0.05717771 11 18339564 18339657 94 + 1.290 1.084 -0.730
ENSG00000110768 E021 19.2231979 0.0008357590 0.057559759 0.23989089 11 18341261 18341408 148 + 1.348 1.222 -0.442
ENSG00000110768 E022 6.9318746 0.0167349551 0.770232613 0.91144977 11 18341409 18341410 2 + 0.879 0.915 0.140
ENSG00000110768 E023 0.2537694 0.0160874025 0.131129543   11 18341411 18341527 117 + 0.000 0.205 12.025
ENSG00000110768 E024 12.8155541 0.0082396943 0.269757036 0.56334381 11 18341528 18341607 80 + 1.091 1.189 0.351
ENSG00000110768 E025 1.2505321 0.0101610083 0.010302899 0.08187366 11 18341608 18341958 351 + 0.145 0.533 2.599
ENSG00000110768 E026 1.5977028 0.0084491072 0.316312750 0.60926438 11 18347104 18347587 484 + 0.341 0.493 0.822
ENSG00000110768 E027 14.2477496 0.0010022761 0.664731551 0.86063882 11 18347588 18347715 128 + 1.162 1.198 0.127
ENSG00000110768 E028 12.8785326 0.0013917269 0.949147255 0.98676200 11 18347832 18347919 88 + 1.138 1.135 -0.008
ENSG00000110768 E029 6.0568610 0.0773418429 0.025200961 0.14613360 11 18347920 18348831 912 + 0.679 1.002 1.258
ENSG00000110768 E030 3.9094277 0.0599635267 0.504787060 0.76382979 11 18351572 18351880 309 + 0.641 0.742 0.419
ENSG00000110768 E031 18.5643030 0.0010738370 0.123286680 0.37171272 11 18351881 18351969 89 + 1.238 1.344 0.371
ENSG00000110768 E032 0.4917399 0.0158920147 0.684698338   11 18352018 18352097 80 + 0.145 0.205 0.599
ENSG00000110768 E033 0.7328615 0.0482107999 0.631218028 0.84185375 11 18352098 18352328 231 + 0.203 0.280 0.600
ENSG00000110768 E034 21.6149343 0.0161725030 0.232161143 0.52082515 11 18352329 18352446 118 + 1.307 1.400 0.321
ENSG00000110768 E035 17.3904798 0.0152040736 0.057189191 0.23901636 11 18357952 18358042 91 + 1.185 1.344 0.558
ENSG00000110768 E036 0.2457744 0.0164259686 0.750513260   11 18358043 18358102 60 + 0.079 0.114 0.599
ENSG00000110768 E037 19.5214764 0.0031156477 0.206833761 0.49047538 11 18358525 18358640 116 + 1.267 1.356 0.310
ENSG00000110768 E038 0.0000000       11 18358641 18358642 2 +      
ENSG00000110768 E039 17.4496489 0.0007998658 0.342684192 0.63409890 11 18360615 18360707 93 + 1.285 1.222 -0.224
ENSG00000110768 E040 0.0000000       11 18360708 18360770 63 +      
ENSG00000110768 E041 117.6236961 0.0001886250 0.009382312 0.07711454 11 18365783 18367089 1307 + 2.040 2.105 0.217

Help

Please Click HERE to learn more details about the results from DEXseq.