ENSG00000110921

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000228510 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding protein_coding 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 3.85556309 0.8839561 5.4442304 0.3630588 0.4670000 2.6090997 0.53757500 0.322575 0.672175 0.349600 0.391140035 0.003280921 FALSE TRUE
ENST00000535044 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding protein_coding_CDS_not_defined 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 0.40336857 0.0000000 1.2101057 0.0000000 1.2101057 6.9308623 0.03467500 0.000000 0.104025 0.104025 0.952831925 0.003280921 FALSE FALSE
ENST00000540353 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding retained_intron 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 0.65788726 0.4043133 0.4930028 0.1361083 0.1672438 0.2798444 0.10975000 0.137550 0.061950 -0.075600 0.828517170 0.003280921 FALSE FALSE
ENST00000545516 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding retained_intron 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 0.81235309 1.3257361 0.0000000 0.4499258 0.0000000 -7.0614912 0.14920833 0.333900 0.000000 -0.333900 0.003280921 0.003280921   FALSE
ENST00000545774 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding nonsense_mediated_decay 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 0.20142197 0.3114362 0.0000000 0.3114362 0.0000000 -5.0064606 0.03595833 0.071025 0.000000 -0.071025 0.722242341 0.003280921 TRUE FALSE
ENST00000636996 ENSG00000110921 No_inf pgKDN_inf MVK protein_coding protein_coding 6.743166 3.423901 8.329969 0.5716009 1.132719 1.280193 0.08207218 0.2462165 0.0000000 0.2462165 0.0000000 -4.6792917 0.02227500 0.066825 0.000000 -0.066825 0.716681403 0.003280921 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110921 E001 0.0000000       12 109573255 109573279 25 +      
ENSG00000110921 E002 0.0000000       12 109573280 109573340 61 +      
ENSG00000110921 E003 0.0000000       12 109573341 109573571 231 +      
ENSG00000110921 E004 0.2352613 0.159321304 1.000000e+00   12 109573793 109573793 1 + 0.103 0.000 -9.590
ENSG00000110921 E005 0.3539644 0.018882764 6.224661e-01   12 109573794 109573804 11 + 0.147 0.000 -11.798
ENSG00000110921 E006 0.6084891 0.108228589 4.372336e-01 7.135284e-01 12 109573805 109573813 9 + 0.147 0.277 1.146
ENSG00000110921 E007 0.9624535 0.322539890 8.896973e-01 9.632796e-01 12 109573814 109573831 18 + 0.257 0.277 0.146
ENSG00000110921 E008 1.1997948 0.013377359 7.830348e-01 9.165837e-01 12 109573832 109573836 5 + 0.317 0.277 -0.270
ENSG00000110921 E009 1.6818380 0.037111069 8.554672e-01 9.491620e-01 12 109573837 109573873 37 + 0.394 0.369 -0.144
ENSG00000110921 E010 0.4818259 0.016027849 1.000000e+00   12 109573918 109574808 891 + 0.147 0.160 0.145
ENSG00000110921 E011 1.4465767 0.013246867 9.158644e-01 9.736317e-01 12 109574809 109574812 4 + 0.344 0.369 0.145
ENSG00000110921 E012 1.6908430 0.009542339 6.764794e-01 8.659259e-01 12 109574813 109574817 5 + 0.370 0.445 0.408
ENSG00000110921 E013 1.4448775 0.009650163 9.170121e-01 9.739400e-01 12 109574818 109574822 5 + 0.344 0.369 0.145
ENSG00000110921 E014 1.3176152 0.010058364 6.580869e-01 8.570560e-01 12 109574823 109574829 7 + 0.344 0.277 -0.439
ENSG00000110921 E015 2.6479168 0.005668952 6.981362e-01 8.768537e-01 12 109574830 109574900 71 + 0.498 0.565 0.315
ENSG00000110921 E016 5.0095706 0.027140552 2.917037e-01 5.851242e-01 12 109575998 109576145 148 + 0.756 0.615 -0.591
ENSG00000110921 E017 0.0000000       12 109579165 109579282 118 +      
ENSG00000110921 E018 5.6994060 0.019236235 2.224304e-02 1.356226e-01 12 109579802 109579946 145 + 0.831 0.509 -1.373
ENSG00000110921 E019 3.6862836 0.008653047 1.312129e-01 3.842975e-01 12 109581395 109581478 84 + 0.665 0.445 -1.024
ENSG00000110921 E020 3.3749580 0.004971989 5.527315e-01 7.961308e-01 12 109581479 109581550 72 + 0.567 0.660 0.408
ENSG00000110921 E021 6.2232650 0.002544894 4.283031e-01 7.068573e-01 12 109586022 109586125 104 + 0.822 0.737 -0.340
ENSG00000110921 E022 4.2942960 0.004471148 1.401082e-01 3.981975e-01 12 109586754 109586799 46 + 0.713 0.509 -0.902
ENSG00000110921 E023 0.9968852 0.119007982 5.119563e-03 5.050640e-02 12 109586800 109587099 300 + 0.103 0.565 3.316
ENSG00000110921 E024 1.6048778 0.010481141 3.946770e-03 4.205388e-02 12 109587861 109588443 583 + 0.223 0.660 2.409
ENSG00000110921 E025 9.1836092 0.001684940 4.792518e-07 2.382301e-05 12 109588444 109590682 2239 + 0.786 1.243 1.692
ENSG00000110921 E026 0.1268540 0.012547227 1.374653e-01   12 109590683 109590770 88 + 0.000 0.160 12.785
ENSG00000110921 E027 5.1252140 0.011561557 4.872712e-02 2.174997e-01 12 109590771 109590845 75 + 0.786 0.509 -1.196
ENSG00000110921 E028 2.8550177 0.005543584 4.787600e-02 2.152863e-01 12 109590846 109590861 16 + 0.597 0.277 -1.729
ENSG00000110921 E029 0.1176306 0.011853251 1.000000e+00   12 109590862 109591240 379 + 0.055 0.000 -10.405
ENSG00000110921 E030 6.0641324 0.002456024 9.067852e-03 7.544757e-02 12 109591241 109591357 117 + 0.856 0.509 -1.471
ENSG00000110921 E031 0.4828984 0.017454141 1.000000e+00   12 109593759 109595027 1269 + 0.147 0.160 0.145
ENSG00000110921 E032 6.5666731 0.002310922 1.716629e-01 4.442856e-01 12 109595028 109595181 154 + 0.856 0.700 -0.623
ENSG00000110921 E033 22.2932819 0.035345320 3.054952e-01 5.987669e-01 12 109596426 109598125 1700 + 1.276 1.383 0.375

Help

Please Click HERE to learn more details about the results from DEXseq.