ENSG00000110934

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000605039 ENSG00000110934 No_inf pgKDN_inf BIN2 protein_coding retained_intron 64.66823 73.39689 66.82313 0.4504679 1.400641 -0.135352 6.294538 11.667680 3.724593 1.5085899 0.4313340 -1.6447306 0.09323333 0.158675 0.055850 -0.102825 0.03024438 0.03024438 FALSE TRUE
ENST00000615107 ENSG00000110934 No_inf pgKDN_inf BIN2 protein_coding protein_coding 64.66823 73.39689 66.82313 0.4504679 1.400641 -0.135352 46.775264 48.195904 51.676802 2.9823348 2.8946751 0.1005861 0.72695833 0.657250 0.772400 0.115150 0.33871755 0.03024438 FALSE TRUE
MSTRG.6516.1 ENSG00000110934 No_inf pgKDN_inf BIN2 protein_coding   64.66823 73.39689 66.82313 0.4504679 1.400641 -0.135352 5.012189 3.102956 7.982123 0.9831369 0.9703216 1.3602935 0.07851667 0.042175 0.119775 0.077600 0.16493508 0.03024438 FALSE TRUE
MSTRG.6516.8 ENSG00000110934 No_inf pgKDN_inf BIN2 protein_coding   64.66823 73.39689 66.82313 0.4504679 1.400641 -0.135352 3.030992 6.400027 0.842997 2.3208448 0.8429970 -2.9097177 0.04509167 0.086975 0.012850 -0.074125 0.27444527 0.03024438 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110934 E001 0.0000000       12 51280964 51281037 74 -      
ENSG00000110934 E002 0.7621583 0.0131991764 1.690284e-02 1.134272e-01 12 51281038 51281039 2 - 0.000 0.370 12.188
ENSG00000110934 E003 65.8592421 0.0003005518 1.643323e-01 4.336152e-01 12 51281040 51281281 242 - 1.848 1.800 -0.163
ENSG00000110934 E004 101.0347379 0.0001819324 1.067806e-03 1.574986e-02 12 51281282 51281528 247 - 1.947 2.046 0.335
ENSG00000110934 E005 53.6845175 0.0070810736 4.741111e-02 2.139629e-01 12 51284716 51284780 65 - 1.669 1.779 0.372
ENSG00000110934 E006 25.9549443 0.0064811557 6.551731e-01 8.553712e-01 12 51284781 51284787 7 - 1.408 1.442 0.117
ENSG00000110934 E007 49.3049043 0.0003264932 6.686075e-01 8.619945e-01 12 51288108 51288188 81 - 1.686 1.707 0.071
ENSG00000110934 E008 218.7932005 0.0001193265 3.130752e-01 6.063941e-01 12 51291591 51292161 571 - 2.326 2.348 0.073
ENSG00000110934 E009 51.3967762 0.0045108066 3.025729e-01 5.956915e-01 12 51292162 51292201 40 - 1.743 1.694 -0.165
ENSG00000110934 E010 73.5937564 0.0002108229 8.838716e-01 9.609464e-01 12 51292202 51292309 108 - 1.871 1.868 -0.008
ENSG00000110934 E011 44.0857985 0.0005225692 1.308963e-01 3.837662e-01 12 51292310 51292341 32 - 1.686 1.621 -0.222
ENSG00000110934 E012 32.4965062 0.0139547953 7.585874e-01 9.051739e-01 12 51292342 51292344 3 - 1.537 1.510 -0.090
ENSG00000110934 E013 71.3747399 0.0026712475 4.138991e-01 6.943862e-01 12 51295796 51295878 83 - 1.874 1.842 -0.105
ENSG00000110934 E014 57.9411885 0.0002629753 7.701582e-02 2.839194e-01 12 51297089 51297164 76 - 1.803 1.737 -0.224
ENSG00000110934 E015 0.8774339 0.2853411644 1.829554e-01 4.596382e-01 12 51297165 51297373 209 - 0.103 0.370 2.331
ENSG00000110934 E016 57.4206447 0.0003400360 2.666709e-02 1.514215e-01 12 51299203 51299288 86 - 1.809 1.724 -0.285
ENSG00000110934 E017 67.5404140 0.0002562082 6.644056e-01 8.605060e-01 12 51299607 51299714 108 - 1.840 1.827 -0.044
ENSG00000110934 E018 49.4803797 0.0003580114 7.024096e-01 8.789720e-01 12 51302020 51302115 96 - 1.707 1.694 -0.046
ENSG00000110934 E019 20.0211799 0.0025763071 8.276313e-11 8.406303e-09 12 51302116 51302517 402 - 0.980 1.473 1.746
ENSG00000110934 E020 12.3491580 0.0012058937 1.487193e-05 4.817432e-04 12 51302518 51302685 168 - 0.870 1.251 1.390
ENSG00000110934 E021 33.9779186 0.0004115199 1.312422e-02 9.596631e-02 12 51302686 51302716 31 - 1.605 1.482 -0.421
ENSG00000110934 E022 37.5972731 0.0003689046 2.017152e-03 2.572549e-02 12 51302717 51302780 64 - 1.659 1.513 -0.498
ENSG00000110934 E023 34.6085990 0.0004028682 2.866094e-02 1.585273e-01 12 51303087 51303141 55 - 1.605 1.498 -0.367
ENSG00000110934 E024 0.7620323 0.0137199624 1.695399e-02 1.136743e-01 12 51304120 51304265 146 - 0.000 0.370 14.463
ENSG00000110934 E025 36.6202355 0.0004300391 9.568593e-01 9.897505e-01 12 51313823 51313903 81 - 1.569 1.574 0.018
ENSG00000110934 E026 0.7349988 0.0145435977 8.249562e-01 9.365893e-01 12 51322585 51322747 163 - 0.256 0.223 -0.254
ENSG00000110934 E027 1.1164697 0.0157120806 4.673205e-01 7.357802e-01 12 51322748 51323088 341 - 0.256 0.370 0.746
ENSG00000110934 E028 0.7626313 0.0257244511 1.777759e-02 1.173295e-01 12 51323089 51323258 170 - 0.000 0.370 14.326
ENSG00000110934 E029 29.2852753 0.0038331684 5.347499e-01 7.846452e-01 12 51324022 51324186 165 - 1.455 1.495 0.136
ENSG00000110934 E030 0.0000000       12 51324513 51324668 156 -      

Help

Please Click HERE to learn more details about the results from DEXseq.