ENSG00000110987

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261822 ENSG00000110987 No_inf pgKDN_inf BCL7A protein_coding protein_coding 5.62021 5.908408 5.790226 0.3426904 0.2109532 -0.02910011 3.1867992 1.323661 5.0760098 0.8790040 0.2960858 1.931142 0.5733167 0.244775 0.87585 0.631075 0.05330779 0.02411745 FALSE TRUE
ENST00000538010 ENSG00000110987 No_inf pgKDN_inf BCL7A protein_coding protein_coding 5.62021 5.908408 5.790226 0.3426904 0.2109532 -0.02910011 0.8501458 1.268674 0.6012069 0.1725663 0.1459939 -1.064916 0.1511917 0.212225 0.10595 -0.106275 0.65002747 0.02411745 FALSE TRUE
MSTRG.7353.4 ENSG00000110987 No_inf pgKDN_inf BCL7A protein_coding   5.62021 5.908408 5.790226 0.3426904 0.2109532 -0.02910011 1.3448836 2.934880 0.0000000 1.0467726 0.0000000 -8.202065 0.2363500 0.482150 0.00000 -0.482150 0.02411745 0.02411745 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000110987 E001 8.8277052 0.001711461 0.001732616 0.02284794 12 122019422 122021883 2462 + 0.806 1.102 1.107
ENSG00000110987 E002 0.2541163 0.016521912 0.279484426   12 122021884 122021977 94 + 0.000 0.166 10.028
ENSG00000110987 E003 3.4223568 0.006769141 0.516924883 0.77255117 12 122021978 122022183 206 + 0.687 0.605 -0.351
ENSG00000110987 E004 3.1832215 0.013599850 0.793798944 0.92137804 12 122030700 122030781 82 + 0.638 0.605 -0.144
ENSG00000110987 E005 3.8879119 0.004245277 0.174464029 0.44818018 12 122035331 122035427 97 + 0.770 0.605 -0.692
ENSG00000110987 E006 0.1272623 0.012374237 0.595863220   12 122043263 122043317 55 + 0.000 0.091 9.094
ENSG00000110987 E007 5.1387892 0.003223830 0.734915024 0.89481910 12 122043886 122044053 168 + 0.806 0.770 -0.144
ENSG00000110987 E008 0.3729107 0.018575274 0.650389602   12 122044054 122044371 318 + 0.099 0.166 0.856
ENSG00000110987 E009 4.3864787 0.003658518 0.187154528 0.46505378 12 122054805 122054926 122 + 0.806 0.652 -0.630
ENSG00000110987 E010 0.6003758 0.211071365 0.202399109 0.48481019 12 122054927 122054989 63 + 0.307 0.091 -2.145
ENSG00000110987 E011 87.5914924 0.000248632 0.814476613 0.93227746 12 122059092 122062044 2953 + 1.947 1.945 -0.007

Help

Please Click HERE to learn more details about the results from DEXseq.