ENSG00000111249

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261726 ENSG00000111249 No_inf pgKDN_inf CUX2 protein_coding protein_coding 28.89285 76.89649 0.850838 27.99143 0.1157684 -6.48122 1.416401 2.843787 0.850838 0.06549449 0.1157684 -1.729064 0.6617417 0.229575 1 0.770425 0.004252561 0.004252561 FALSE TRUE
MSTRG.7176.6 ENSG00000111249 No_inf pgKDN_inf CUX2 protein_coding   28.89285 76.89649 0.850838 27.99143 0.1157684 -6.48122 27.314245 73.566078 0.000000 27.89277509 0.0000000 -12.845021 0.3228917 0.724325 0 -0.724325 0.144649563 0.004252561   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111249 E001 0.1176306 0.011803000 0.105092404   12 111034165 111034240 76 + 0.166 0.000 -11.959
ENSG00000111249 E002 0.0000000       12 111099446 111099636 191 +      
ENSG00000111249 E003 0.0000000       12 111099930 111100117 188 +      
ENSG00000111249 E004 0.0000000       12 111214200 111214300 101 +      
ENSG00000111249 E005 0.1265070 0.012644667 1.000000000   12 111214301 111214310 10 + 0.000 0.053 10.552
ENSG00000111249 E006 0.1265070 0.012644667 1.000000000   12 111217890 111217937 48 + 0.000 0.053 10.552
ENSG00000111249 E007 0.0000000       12 111263761 111263839 79 +      
ENSG00000111249 E008 0.2458395 0.016929591 0.287729414   12 111270230 111270654 425 + 0.166 0.053 -1.852
ENSG00000111249 E009 0.2533610 0.016336417 1.000000000   12 111291418 111291552 135 + 0.000 0.100 11.421
ENSG00000111249 E010 0.1268540 0.012594053 1.000000000   12 111293446 111293569 124 + 0.000 0.053 10.552
ENSG00000111249 E011 0.0000000       12 111295333 111295409 77 +      
ENSG00000111249 E012 0.0000000       12 111296473 111296539 67 +      
ENSG00000111249 E013 0.0000000       12 111298541 111298589 49 +      
ENSG00000111249 E014 0.0000000       12 111304210 111304314 105 +      
ENSG00000111249 E015 1.0162746 0.011687246 0.138589408 0.39588375 12 111306921 111307112 192 + 0.000 0.308 13.012
ENSG00000111249 E016 0.0000000       12 111307199 111307257 59 +      
ENSG00000111249 E017 0.1268540 0.012594053 1.000000000   12 111308266 111308284 19 + 0.000 0.053 10.552
ENSG00000111249 E018 0.1268540 0.012594053 1.000000000   12 111308285 111308333 49 + 0.000 0.053 10.552
ENSG00000111249 E019 0.5070689 0.126353832 0.584764776 0.81539604 12 111308334 111308426 93 + 0.000 0.180 12.186
ENSG00000111249 E020 0.5070689 0.126353832 0.584764776 0.81539604 12 111308427 111308526 100 + 0.000 0.180 12.186
ENSG00000111249 E021 3.3921217 0.004754551 0.423492743 0.70276784 12 111310041 111310682 642 + 0.456 0.598 0.672
ENSG00000111249 E022 0.4979070 0.022334682 0.826997296   12 111312100 111312166 67 + 0.166 0.142 -0.267
ENSG00000111249 E023 0.6243526 0.021324790 1.000000000 1.00000000 12 111312167 111312201 35 + 0.166 0.181 0.148
ENSG00000111249 E024 1.5237519 0.009142864 0.043924547 0.20477366 12 111313779 111313896 118 + 0.000 0.406 13.438
ENSG00000111249 E025 4.1913665 0.003705933 0.005949308 0.05613541 12 111320012 111320775 764 + 0.876 0.553 -1.337
ENSG00000111249 E026 2.0963308 0.032181884 0.064859272 0.25664857 12 111322421 111322580 160 + 0.629 0.360 -1.337
ENSG00000111249 E027 2.3414489 0.006541937 0.033930490 0.17540058 12 111334441 111334710 270 + 0.674 0.383 -1.392
ENSG00000111249 E028 2.3911401 0.114902257 0.317269271 0.61006100 12 111338286 111338474 189 + 0.286 0.504 1.235
ENSG00000111249 E029 3.1385074 0.005077679 0.540860812 0.78868657 12 111341780 111342053 274 + 0.456 0.569 0.541
ENSG00000111249 E030 52.4450228 0.000392244 0.394538234 0.67934186 12 111347524 111350554 3031 + 1.598 1.646 0.166

Help

Please Click HERE to learn more details about the results from DEXseq.