ENSG00000111252

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341259 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding protein_coding 82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 21.365621 4.203604 30.7361362 1.6891094 1.0336519 2.8672784 0.22698333 0.099400 0.287675 0.188275 0.18668962 0.0481688 FALSE  
ENST00000538307 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding protein_coding 82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 41.158964 22.531516 50.7480013 2.3175301 3.2884749 1.1710507 0.50386667 0.532100 0.473925 -0.058175 0.82971509 0.0481688 FALSE  
MSTRG.7197.1 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding   82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 1.912976 2.487627 0.6756674 0.5978923 0.6756674 -1.8649771 0.03065833 0.059350 0.006575 -0.052775 0.04816880 0.0481688 TRUE  
MSTRG.7197.2 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding   82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 8.821844 3.062796 17.2686203 1.7737730 2.0751140 2.4913640 0.09781667 0.069875 0.162100 0.092225 0.42898664 0.0481688 FALSE  
MSTRG.7197.6 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding   82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 3.614979 3.758231 2.1652610 1.7331295 1.0847149 -0.7926990 0.05320000 0.090125 0.019950 -0.070175 0.66458854 0.0481688 FALSE  
MSTRG.7197.8 ENSG00000111252 No_inf pgKDN_inf SH2B3 protein_coding   82.89915 42.48631 106.9303 0.8961238 1.341393 1.331396 3.236033 3.374238 1.9774102 0.8542333 0.2391748 -0.7679411 0.04708333 0.078825 0.018500 -0.060325 0.08213713 0.0481688 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111252 E001 0.2533610 1.597394e-02 6.216786e-02   12 111405907 111405918 12 + 0.000 0.243 10.452
ENSG00000111252 E002 0.4989181 2.491413e-02 6.847037e-02   12 111405919 111405922 4 + 0.064 0.327 2.811
ENSG00000111252 E003 0.4989181 2.491413e-02 6.847037e-02   12 111405923 111405928 6 + 0.064 0.327 2.811
ENSG00000111252 E004 37.0440760 5.865297e-04 6.914556e-02 2.656858e-01 12 111405929 111406277 349 + 1.578 1.480 -0.334
ENSG00000111252 E005 27.1649933 3.257203e-03 5.318004e-02 2.294937e-01 12 111418119 111418339 221 + 1.455 1.327 -0.445
ENSG00000111252 E006 66.0047607 2.327209e-04 4.926280e-05 1.312717e-03 12 111418340 111418877 538 + 1.841 1.673 -0.569
ENSG00000111252 E007 2.6114869 5.404379e-02 5.753043e-04 9.742060e-03 12 111420119 111420408 290 + 0.292 0.821 2.548
ENSG00000111252 E008 2.9551916 7.180012e-03 4.888301e-03 4.877810e-02 12 111420409 111420488 80 + 0.415 0.795 1.712
ENSG00000111252 E009 0.9812463 8.465005e-02 2.793144e-01 5.725787e-01 12 111434862 111435027 166 + 0.215 0.398 1.226
ENSG00000111252 E010 3.3057555 5.298101e-02 9.144978e-02 3.140410e-01 12 111444739 111444858 120 + 0.511 0.769 1.120
ENSG00000111252 E011 11.2607198 1.376012e-02 5.926462e-09 4.372610e-07 12 111445384 111446216 833 + 0.798 1.356 2.040
ENSG00000111252 E012 22.7037875 7.326627e-04 5.837803e-02 2.419364e-01 12 111446753 111446854 102 + 1.381 1.252 -0.452
ENSG00000111252 E013 39.4429902 4.457474e-04 7.008964e-01 8.781802e-01 12 111446942 111447033 92 + 1.581 1.563 -0.062
ENSG00000111252 E014 6.2889220 3.759168e-02 9.229336e-01 9.763295e-01 12 111447122 111447124 3 + 0.830 0.845 0.056
ENSG00000111252 E015 35.3410758 7.089164e-04 7.068075e-01 8.810223e-01 12 111447125 111447219 95 + 1.535 1.516 -0.065
ENSG00000111252 E016 82.3446016 7.912997e-04 6.207019e-01 8.360873e-01 12 111447330 111447544 215 + 1.895 1.878 -0.056
ENSG00000111252 E017 86.4948599 6.766266e-04 9.817877e-01 9.983171e-01 12 111447656 111447827 172 + 1.910 1.911 0.003
ENSG00000111252 E018 1299.8161402 7.078199e-05 1.264126e-01 3.768691e-01 12 111447983 111451688 3706 + 3.079 3.088 0.029

Help

Please Click HERE to learn more details about the results from DEXseq.