ENSG00000111481

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262061 ENSG00000111481 No_inf pgKDN_inf COPZ1 protein_coding protein_coding 114.0393 80.82686 145.3471 3.62582 5.02897 0.8465164 60.36012 57.732216 68.11555 3.331291 1.537844 0.2385695 0.5566250 0.713525 0.47080 -0.242725 2.702848e-06 2.702848e-06 FALSE TRUE
ENST00000548076 ENSG00000111481 No_inf pgKDN_inf COPZ1 protein_coding protein_coding_CDS_not_defined 114.0393 80.82686 145.3471 3.62582 5.02897 0.8465164 22.06331 15.486868 36.34921 5.481100 5.647892 1.2303443 0.1810583 0.183475 0.24795 0.064475 8.305917e-01 2.702848e-06   FALSE
ENST00000550027 ENSG00000111481 No_inf pgKDN_inf COPZ1 protein_coding retained_intron 114.0393 80.82686 145.3471 3.62582 5.02897 0.8465164 22.22868 1.387647 33.82038 1.387647 6.941861 4.5972476 0.1742000 0.019825 0.23195 0.212125 1.645948e-03 2.702848e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111481 E001 0.0000000       12 54301202 54301219 18 +      
ENSG00000111481 E002 0.0000000       12 54301220 54301380 161 +      
ENSG00000111481 E003 0.0000000       12 54325083 54325108 26 +      
ENSG00000111481 E004 0.1170040 1.168470e-02 6.415444e-01   12 54325109 54325128 20 + 0.088 0.000 -10.477
ENSG00000111481 E005 0.1170040 1.168470e-02 6.415444e-01   12 54325129 54325130 2 + 0.088 0.000 -12.342
ENSG00000111481 E006 1.9189110 7.411164e-02 1.424034e-01 4.015467e-01 12 54325131 54325138 8 + 0.567 0.316 -1.332
ENSG00000111481 E007 4.5722750 3.062357e-03 1.558447e-02 1.078956e-01 12 54325139 54325143 5 + 0.862 0.565 -1.233
ENSG00000111481 E008 7.7077822 1.839952e-03 4.547729e-03 4.636225e-02 12 54325144 54325150 7 + 1.054 0.764 -1.101
ENSG00000111481 E009 35.6834897 3.788484e-04 1.390412e-05 4.544876e-04 12 54325151 54325181 31 + 1.655 1.434 -0.755
ENSG00000111481 E010 0.0000000       12 54325202 54325276 75 +      
ENSG00000111481 E011 0.0000000       12 54325584 54325682 99 +      
ENSG00000111481 E012 0.0000000       12 54340372 54340462 91 +      
ENSG00000111481 E013 0.8629525 1.526071e-02 5.449334e-01 7.910820e-01 12 54340463 54340546 84 + 0.223 0.316 0.667
ENSG00000111481 E014 53.8147223 2.995631e-04 2.315486e-05 6.980626e-04 12 54340547 54340615 69 + 1.812 1.638 -0.590
ENSG00000111481 E015 61.2769723 3.045763e-04 1.646085e-01 4.339039e-01 12 54342206 54342287 82 + 1.818 1.765 -0.181
ENSG00000111481 E016 1.1092003 2.204027e-02 5.572122e-01 7.992522e-01 12 54342288 54342630 343 + 0.278 0.368 0.574
ENSG00000111481 E017 67.8718129 3.275633e-03 6.111736e-02 2.482904e-01 12 54343225 54343316 92 + 1.874 1.794 -0.270
ENSG00000111481 E018 45.8671774 4.598538e-03 1.874667e-01 4.655935e-01 12 54345460 54345515 56 + 1.702 1.633 -0.234
ENSG00000111481 E019 0.3543453 1.574380e-02 1.420552e-01   12 54346612 54346674 63 + 0.223 0.000 -13.830
ENSG00000111481 E020 59.7648080 2.551070e-04 6.885526e-01 8.717612e-01 12 54347767 54347844 78 + 1.791 1.775 -0.055
ENSG00000111481 E021 0.1265070 1.221039e-02 4.501418e-01   12 54347845 54347972 128 + 0.000 0.103 11.685
ENSG00000111481 E022 49.2215104 3.009253e-04 2.590724e-01 5.516092e-01 12 54348000 54348039 40 + 1.723 1.674 -0.165
ENSG00000111481 E023 39.0577959 3.720975e-04 1.050565e-01 3.389638e-01 12 54348040 54348051 12 + 1.637 1.559 -0.266
ENSG00000111481 E024 0.5072867 3.851456e-02 3.146482e-02 1.674419e-01 12 54348052 54348132 81 + 0.000 0.316 13.377
ENSG00000111481 E025 51.7274410 2.951253e-04 6.742651e-01 8.650083e-01 12 54349620 54349658 39 + 1.730 1.712 -0.062
ENSG00000111481 E026 0.5979213 3.550588e-02 2.479307e-01 5.387115e-01 12 54349659 54350245 587 + 0.278 0.103 -1.748
ENSG00000111481 E027 1.1236141 2.057134e-02 5.370609e-02 2.306999e-01 12 54350246 54350475 230 + 0.161 0.458 2.059
ENSG00000111481 E028 436.8428532 6.697128e-05 1.313021e-17 2.821373e-15 12 54350476 54351846 1371 + 2.596 2.686 0.300

Help

Please Click HERE to learn more details about the results from DEXseq.