ENSG00000111530

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000535146 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding retained_intron 20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 1.4695415 1.549703 0.4939219 0.8976193 0.4939219 -1.6299994 0.06858333 0.086125 0.018775 -0.067350 0.74551284 0.02112687 FALSE FALSE
ENST00000539109 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding protein_coding_CDS_not_defined 20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 1.6860614 1.187936 2.1611966 0.2360940 0.4416319 0.8579390 0.08199167 0.076875 0.093425 0.016550 0.88703364 0.02112687   FALSE
ENST00000539434 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding retained_intron 20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 1.6015882 1.237250 1.5566118 0.3755697 0.5414342 0.3288971 0.07722500 0.076650 0.065675 -0.010975 0.92759345 0.02112687 FALSE TRUE
ENST00000540319 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding nonsense_mediated_decay 20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 5.2535970 3.978803 6.6337896 0.1990430 0.6844045 0.7360505 0.26630833 0.267375 0.297225 0.029850 0.92404890 0.02112687 TRUE TRUE
ENST00000545606 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding protein_coding 20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 9.0972851 5.653265 11.4875858 0.6205657 0.2576007 1.0216250 0.45234167 0.383250 0.511450 0.128200 0.65383069 0.02112687 FALSE TRUE
MSTRG.6781.6 ENSG00000111530 No_inf pgKDN_inf CAND1 protein_coding   20.06847 15.39668 22.64989 1.507228 1.269132 0.5565853 0.5965726 1.789718 0.0000000 0.6386147 0.0000000 -7.4916270 0.03658333 0.109750 0.000000 -0.109750 0.02112687 0.02112687 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111530 E001 0.4817608 0.0250788536 0.5114144277   12 67269358 67269389 32 + 0.210 0.110 -1.103
ENSG00000111530 E002 9.0633175 0.0051519361 0.1578482552 0.424629049 12 67269390 67269717 328 + 1.055 0.915 -0.518
ENSG00000111530 E003 2.9177304 0.1983912724 0.8546409742 0.948734319 12 67269718 67269725 8 + 0.591 0.590 -0.002
ENSG00000111530 E004 5.0900217 0.0429176503 0.5576102317 0.799451968 12 67269726 67269785 60 + 0.819 0.727 -0.366
ENSG00000111530 E005 0.3533378 0.0157726666 0.1872089825   12 67269901 67270260 360 + 0.210 0.000 -10.209
ENSG00000111530 E006 1.7040650 0.0077797739 0.9251259088 0.977370488 12 67270431 67270795 365 + 0.424 0.437 0.067
ENSG00000111530 E007 12.2581210 0.0163905660 0.0010510845 0.015565401 12 67281910 67282053 144 + 1.234 0.900 -1.219
ENSG00000111530 E008 0.0000000       12 67282054 67282176 123 +      
ENSG00000111530 E009 16.3246060 0.0009174412 0.0320309599 0.169268841 12 67292622 67292776 155 + 1.298 1.138 -0.566
ENSG00000111530 E010 2.0751853 0.0066506981 0.6542243921 0.854867763 12 67292777 67293189 413 + 0.457 0.520 0.312
ENSG00000111530 E011 1.2347984 0.0101872761 0.2477425950 0.538484998 12 67294246 67294284 39 + 0.262 0.437 1.067
ENSG00000111530 E012 1.1154633 0.0119334322 0.1349662601 0.390581653 12 67294955 67295019 65 + 0.210 0.437 1.482
ENSG00000111530 E013 0.9947790 0.1102806477 0.0892215681 0.310076426 12 67295020 67295032 13 + 0.150 0.437 2.067
ENSG00000111530 E014 13.6948970 0.0022919888 0.2584581092 0.550793285 12 67295033 67295156 124 + 1.202 1.109 -0.330
ENSG00000111530 E015 25.7861528 0.0005816397 0.7595576562 0.905625790 12 67297407 67297663 257 + 1.433 1.413 -0.069
ENSG00000111530 E016 13.4490349 0.0015360985 0.2350798242 0.524220427 12 67297748 67297853 106 + 1.196 1.099 -0.346
ENSG00000111530 E017 7.2104804 0.0277600790 0.0417772208 0.198853819 12 67298950 67298971 22 + 1.005 0.750 -0.977
ENSG00000111530 E018 18.6997726 0.0125793012 0.0233633951 0.139636675 12 67298972 67299095 124 + 1.365 1.173 -0.674
ENSG00000111530 E019 39.4327358 0.0004737478 0.9806059456 0.997864842 12 67302323 67302615 293 + 1.604 1.603 -0.003
ENSG00000111530 E020 17.6585582 0.0007972292 0.7784722622 0.914866436 12 67304605 67304681 77 + 1.260 1.277 0.061
ENSG00000111530 E021 17.2915229 0.0008078062 0.8747658294 0.957156635 12 67304682 67304746 65 + 1.255 1.264 0.031
ENSG00000111530 E022 35.3913014 0.0116880833 0.8386191672 0.942106797 12 67305104 67305312 209 + 1.564 1.549 -0.050
ENSG00000111530 E023 40.6572600 0.0009363073 0.1377812412 0.395039441 12 67305313 67305542 230 + 1.646 1.573 -0.248
ENSG00000111530 E024 155.3705412 0.0001553535 0.1971296328 0.478336690 12 67305543 67306597 1055 + 2.204 2.173 -0.104
ENSG00000111530 E025 28.3172055 0.0006071643 0.6025920977 0.826575743 12 67307397 67307492 96 + 1.477 1.446 -0.108
ENSG00000111530 E026 44.6839910 0.0003501132 0.9695037813 0.993749709 12 67309901 67310070 170 + 1.656 1.656 -0.002
ENSG00000111530 E027 41.2120311 0.0004547388 0.0275815636 0.154892134 12 67310152 67310316 165 + 1.576 1.675 0.336
ENSG00000111530 E028 5.4471913 0.0036201812 0.0013728976 0.019134380 12 67310317 67311381 1065 + 0.613 0.973 1.433
ENSG00000111530 E029 33.6419748 0.0004252510 0.0223963068 0.136073270 12 67311693 67311800 108 + 1.483 1.596 0.388
ENSG00000111530 E030 178.2670060 0.0001989775 0.0003542801 0.006664716 12 67312606 67319953 7348 + 2.218 2.288 0.236

Help

Please Click HERE to learn more details about the results from DEXseq.