ENSG00000111596

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000229195 ENSG00000111596 No_inf pgKDN_inf CNOT2 protein_coding protein_coding 33.38455 39.38531 31.42144 2.924004 0.6454535 -0.3258152 19.3044467 20.833992 20.104438 1.5099459 1.2766361 -0.05140018 0.58459167 0.531400 0.642850 0.111450 5.467366e-01 7.504195e-05 FALSE TRUE
ENST00000546673 ENSG00000111596 No_inf pgKDN_inf CNOT2 protein_coding nonsense_mediated_decay 33.38455 39.38531 31.42144 2.924004 0.6454535 -0.3258152 1.5982264 4.607855 0.000000 1.7317520 0.0000000 -8.85107899 0.03934167 0.112050 0.000000 -0.112050 2.609528e-02 7.504195e-05 TRUE TRUE
ENST00000547780 ENSG00000111596 No_inf pgKDN_inf CNOT2 protein_coding protein_coding 33.38455 39.38531 31.42144 2.924004 0.6454535 -0.3258152 0.6555245 0.000000 1.638663 0.0000000 1.0225215 7.36515284 0.02052500 0.000000 0.050350 0.050350 8.105689e-02 7.504195e-05   FALSE
ENST00000550705 ENSG00000111596 No_inf pgKDN_inf CNOT2 protein_coding retained_intron 33.38455 39.38531 31.42144 2.924004 0.6454535 -0.3258152 1.2504942 2.942338 0.000000 0.5114029 0.0000000 -8.20571398 0.03361667 0.073775 0.000000 -0.073775 7.504195e-05 7.504195e-05   FALSE
MSTRG.6853.3 ENSG00000111596 No_inf pgKDN_inf CNOT2 protein_coding   33.38455 39.38531 31.42144 2.924004 0.6454535 -0.3258152 3.2624668 1.253348 4.240312 0.7381674 0.6783089 1.75031711 0.10553333 0.035675 0.134775 0.099100 2.978361e-01 7.504195e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111596 E001 0.0000000       12 70243002 70243029 28 +      
ENSG00000111596 E002 0.0000000       12 70243030 70243120 91 +      
ENSG00000111596 E003 0.0000000       12 70243121 70243189 69 +      
ENSG00000111596 E004 0.0000000       12 70243190 70243237 48 +      
ENSG00000111596 E005 0.0000000       12 70243238 70243332 95 +      
ENSG00000111596 E006 0.0000000       12 70243333 70243368 36 +      
ENSG00000111596 E007 0.0000000       12 70243369 70243409 41 +      
ENSG00000111596 E008 0.0000000       12 70243410 70243411 2 +      
ENSG00000111596 E009 0.0000000       12 70243412 70243420 9 +      
ENSG00000111596 E010 0.0000000       12 70243421 70243423 3 +      
ENSG00000111596 E011 0.0000000       12 70243424 70243424 1 +      
ENSG00000111596 E012 0.0000000       12 70243425 70243432 8 +      
ENSG00000111596 E013 0.0000000       12 70243433 70243435 3 +      
ENSG00000111596 E014 0.1265070 0.0122964303 6.721985e-01   12 70243436 70243437 2 + 0.000 0.086 9.243
ENSG00000111596 E015 1.0990352 0.0138277785 5.075237e-01 0.765886532 12 70243438 70243441 4 + 0.374 0.274 -0.635
ENSG00000111596 E016 1.8249091 0.0075106136 2.309379e-01 0.519382351 12 70243442 70243442 1 + 0.538 0.365 -0.898
ENSG00000111596 E017 2.6927754 0.0055975099 6.004835e-01 0.825092754 12 70243443 70243444 2 + 0.602 0.533 -0.313
ENSG00000111596 E018 2.9467657 0.0049952730 8.865718e-01 0.962080545 12 70243445 70243447 3 + 0.602 0.586 -0.072
ENSG00000111596 E019 3.0736197 0.0051787646 9.715398e-01 0.994533443 12 70243448 70243448 1 + 0.602 0.610 0.035
ENSG00000111596 E020 6.8892865 0.0089900168 8.393456e-01 0.942383310 12 70243449 70243480 32 + 0.878 0.905 0.102
ENSG00000111596 E021 0.0000000       12 70243714 70243747 34 +      
ENSG00000111596 E022 0.0000000       12 70243748 70243750 3 +      
ENSG00000111596 E023 1.2256659 0.1642660146 7.510461e-01 0.901794187 12 70243751 70244189 439 + 0.374 0.322 -0.313
ENSG00000111596 E024 0.1271363 0.0125154683 6.719616e-01   12 70244190 70244322 133 + 0.000 0.086 11.480
ENSG00000111596 E025 17.3587522 0.0007941077 6.527954e-02 0.257198228 12 70278132 70278274 143 + 1.326 1.202 -0.435
ENSG00000111596 E026 0.0000000       12 70278275 70278450 176 +      
ENSG00000111596 E027 0.7373580 0.0640564822 7.935284e-01 0.921262289 12 70285400 70285586 187 + 0.260 0.220 -0.313
ENSG00000111596 E028 0.2542726 0.3345853800 4.088593e-01   12 70290727 70290803 77 + 0.000 0.158 11.815
ENSG00000111596 E029 0.3720293 0.0168199840 7.314495e-01   12 70294071 70294236 166 + 0.105 0.158 0.687
ENSG00000111596 E030 0.7345254 0.0135769086 7.851038e-01 0.917174189 12 70294237 70294294 58 + 0.260 0.220 -0.313
ENSG00000111596 E031 0.7437487 0.0140533229 5.850166e-01 0.815613110 12 70297759 70297879 121 + 0.189 0.274 0.687
ENSG00000111596 E032 0.1268540 0.0122660187 6.722625e-01   12 70301705 70301865 161 + 0.000 0.086 11.481
ENSG00000111596 E033 0.1268540 0.0122660187 6.722625e-01   12 70307698 70307901 204 + 0.000 0.086 11.481
ENSG00000111596 E034 12.5999258 0.0011107435 1.521263e-01 0.415852935 12 70310895 70310962 68 + 1.189 1.078 -0.397
ENSG00000111596 E035 11.6323413 0.0012700257 3.220309e-01 0.615072310 12 70310963 70311017 55 + 1.141 1.062 -0.283
ENSG00000111596 E036 0.0000000       12 70319024 70319297 274 +      
ENSG00000111596 E037 13.3493051 0.0010349676 2.820556e-01 0.575550864 12 70319298 70319364 67 + 1.197 1.117 -0.287
ENSG00000111596 E038 0.0000000       12 70327507 70327700 194 +      
ENSG00000111596 E039 0.0000000       12 70327701 70327715 15 +      
ENSG00000111596 E040 21.7857487 0.0007469351 8.106683e-01 0.930307383 12 70329423 70329570 148 + 1.343 1.361 0.064
ENSG00000111596 E041 0.0000000       12 70329571 70329633 63 +      
ENSG00000111596 E042 27.4226205 0.0005633312 5.017229e-02 0.221312837 12 70330287 70330469 183 + 1.507 1.401 -0.365
ENSG00000111596 E043 5.2782157 0.0048296917 3.919326e-05 0.001081253 12 70330470 70331698 1229 + 0.421 0.950 2.272
ENSG00000111596 E044 2.2225520 0.0081328252 6.431623e-01 0.848695462 12 70332398 70332766 369 + 0.464 0.533 0.339
ENSG00000111596 E045 11.1419143 0.0011830722 2.421193e-01 0.531826249 12 70332767 70332790 24 + 1.132 1.037 -0.345
ENSG00000111596 E046 16.1348369 0.0009812552 4.798608e-02 0.215511781 12 70332791 70332846 56 + 1.303 1.165 -0.488
ENSG00000111596 E047 2.7236439 0.0401873698 4.854557e-01 0.749272205 12 70334435 70335437 1003 + 0.503 0.610 0.494
ENSG00000111596 E048 9.7452996 0.0014529692 1.976995e-02 0.125977402 12 70335438 70335438 1 + 1.132 0.928 -0.749
ENSG00000111596 E049 27.4784917 0.0006289167 3.046618e-03 0.034901512 12 70335439 70335563 125 + 1.535 1.373 -0.557
ENSG00000111596 E050 2.1998962 0.1260115185 4.385480e-01 0.714715219 12 70335564 70337388 1825 + 0.572 0.440 -0.636
ENSG00000111596 E051 23.0125352 0.0007402425 7.630511e-01 0.907575753 12 70337389 70337482 94 + 1.364 1.385 0.075
ENSG00000111596 E052 12.8606799 0.0014571098 1.065700e-01 0.341912023 12 70337483 70337513 31 + 1.056 1.190 0.483
ENSG00000111596 E053 0.0000000       12 70337514 70337755 242 +      
ENSG00000111596 E054 0.6272181 0.0153748485 2.622110e-01 0.555027034 12 70337756 70337820 65 + 0.105 0.274 1.687
ENSG00000111596 E055 1.1267619 0.0113319310 1.685359e-01 0.439882220 12 70337821 70338435 615 + 0.189 0.404 1.494
ENSG00000111596 E056 0.1271363 0.0125154683 6.719616e-01   12 70338436 70338442 7 + 0.000 0.086 11.480
ENSG00000111596 E057 16.0003813 0.0008610086 7.599729e-01 0.905940659 12 70338443 70338473 31 + 1.212 1.237 0.089
ENSG00000111596 E058 24.9434223 0.0110809606 8.883547e-01 0.962722746 12 70338474 70338563 90 + 1.417 1.404 -0.042
ENSG00000111596 E059 0.0000000       12 70338564 70338568 5 +      
ENSG00000111596 E060 27.5337381 0.0005705681 8.358939e-01 0.941133157 12 70338666 70338765 100 + 1.456 1.447 -0.029
ENSG00000111596 E061 22.9550684 0.0006649108 4.641041e-01 0.733678987 12 70338766 70338822 57 + 1.398 1.357 -0.143
ENSG00000111596 E062 0.1265070 0.0122964303 6.721985e-01   12 70341990 70342106 117 + 0.000 0.086 11.481
ENSG00000111596 E063 13.1504294 0.0015813358 9.249402e-01 0.977250896 12 70342107 70342107 1 + 1.149 1.145 -0.015
ENSG00000111596 E064 13.2680601 0.0013342716 8.409401e-01 0.942976132 12 70342108 70342109 2 + 1.157 1.145 -0.045
ENSG00000111596 E065 23.5588353 0.0005799724 2.512535e-01 0.542526758 12 70342110 70342168 59 + 1.343 1.416 0.253
ENSG00000111596 E066 0.0000000       12 70342169 70342257 89 +      
ENSG00000111596 E067 14.2270331 0.0009864501 8.741144e-02 0.306451407 12 70342258 70342268 11 + 1.095 1.231 0.484
ENSG00000111596 E068 17.6964040 0.0008455473 5.112969e-02 0.223869852 12 70342269 70342307 39 + 1.181 1.322 0.494
ENSG00000111596 E069 0.3720642 0.0164796926 7.327159e-01   12 70342308 70342373 66 + 0.105 0.158 0.687
ENSG00000111596 E070 1.1423733 0.0103303876 2.789506e-03 0.032677933 12 70343947 70344110 164 + 0.000 0.474 14.400
ENSG00000111596 E071 1.1335609 0.0135127959 3.210805e-02 0.169493541 12 70344111 70344127 17 + 0.105 0.440 2.687
ENSG00000111596 E072 25.5584339 0.0104454495 1.963826e-01 0.477039081 12 70344128 70344228 101 + 1.364 1.457 0.324
ENSG00000111596 E073 0.0000000       12 70344229 70344239 11 +      
ENSG00000111596 E074 4.1364268 0.0046984531 9.686199e-02 0.324139396 12 70344240 70346066 1827 + 0.810 0.610 -0.828
ENSG00000111596 E075 39.7729763 0.0005604980 4.215293e-01 0.700717005 12 70346180 70346324 145 + 1.625 1.591 -0.117
ENSG00000111596 E076 0.7345602 0.0141598482 7.832179e-01 0.916583712 12 70346325 70346626 302 + 0.260 0.220 -0.313
ENSG00000111596 E077 0.4986623 0.0353098528 4.433544e-01   12 70347594 70348045 452 + 0.105 0.220 1.272
ENSG00000111596 E078 171.4922942 0.0002027494 1.991438e-02 0.126688908 12 70353829 70354993 1165 + 2.202 2.254 0.172

Help

Please Click HERE to learn more details about the results from DEXseq.